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A Modified Cuff Technique for Mouse Cervical Heterotopic Heart Transplantation Model

DOI :

10.3791/63504-v

February 7th, 2022

February 7th, 2022

2,501 Views

1Department of Urological Oncology Surgery, Chongqing University Cancer Hospital, 2School of Medicine, Chongqing University, 3Department of Biochemistry and Molecular Biology, College of Basic Medical Science, Army Medical University

In the present protocol, a mouse heart transplantation model is used for investigating the mechanism of cardiac allograft rejection. In this heterotopic heart transplantation model, operation efficiency is improved, and the survival of cardiac grafts is ensured by a cervical end-to-end anastomosis of heart implantation using a modified Cuff technique.

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Modified Cuff Technique

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