JoVE Logo
Faculty Resource Center

Sign In

TAPE: A Biodegradable Hemostatic Glue Inspired by a Ubiquitous Compound in Plants for Surgical Application

DOI :

10.3791/53930-v

June 8th, 2016

June 8th, 2016

13,799 Views

1The Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology (KAIST), 2Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), 3Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School

We describe the simplest protocol to prepare biodegradable medical glue that has an effective hemostatic ability. TAPE is a water-immiscible supramolecular aggregate prepared by mixing of tannic acid, a ubiquitous compound found in plants, and poly(ethylene) glycol, yielding a 2.5 times greater water-resistant adhesion compared with commercial fibrin glue.

Tags

Keywords TAPE

-- Views

Related Videos

article

Creating Two-Dimensional Patterned Substrates for Protein and Cell Confinement

article

Cellular Lipid Extraction for Targeted Stable Isotope Dilution Liquid Chromatography-Mass Spectrometry Analysis

article

Constructing a Collagen Hydrogel for the Delivery of Stem Cell-loaded Chitosan Microspheres

article

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device

article

Sustained Administration of β-cell Mitogens to Intact Mouse Islets Ex Vivo Using Biodegradable Poly(lactic-co-glycolic acid) Microspheres

article

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies

article

A Novel Surgical Technique As a Foundation for In Vivo Partial Liver Engineering in Rat

article

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

article

Detection of Endotoxin in Nano-formulations Using Limulus Amoebocyte Lysate (LAL) Assays

article

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved