JoVE Logo
Faculty Resource Center

Sign In

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

DOI :

10.3791/53951-v

May 31st, 2016

May 31st, 2016

14,198 Views

1Department of Neurology, University Hospital Wuerzburg, 2Institute of Anatomy and Cell Biology, University Wuerzburg

Deep brain stimulation (DBS) is an effective treatment option for Parkinson's disease. We established a study design to screen novel stimulation paradigms in rats. The protocol describes the use of the staircase test and cylinder test for motor outcome assessment in DBS treated hemiparkinsonian rats.

-- Views

Related Videos

article

Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome

article

Paw-Dragging: a Novel, Sensitive Analysis of the Mouse Cylinder Test

article

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning

article

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

article

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function

article

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants

article

Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain

article

Sit-to-stand-and-walk from 120% Knee Height: A Novel Approach to Assess Dynamic Postural Control Independent of Lead-limb

article

Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet

article

A Within-subjects Experimental Protocol to Assess the Effects of Social Input on Infant EEG

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved