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Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses

DOI :

10.3791/53986-v

May 3rd, 2016

May 3rd, 2016

6,950 Views

1Department of Cell and Molecular Biology, The Scripps Research Institute

Age-related increases in eye lens stiffness are linked to presbyopia. This protocol describes a simple, cost-effective method for measuring mouse lens stiffness. Mouse lenses, like human lenses, become stiffer with age. This method is precise and can be adapted for lenses from larger animals.

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