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Applications of In Vivo Functional Testing of the Rat Tibialis Anterior for Evaluating Tissue Engineered Skeletal Muscle Repair

DOI :

10.3791/54487-v

7:13 min

October 7th, 2016

October 7th, 2016

12,903 Views

1Department of Pathology, University of Virginia, 2Department of Biomedical Engineering, University of Virginia, 3Department of Orthopaedic Surgery, University of Virginia

We describe an in vivo protocol to measure dorsiflexion of the foot following stimulation of the peroneal nerve and contraction of the anterior crural compartment of the rat hindlimb. Such measurements are an indispensable translational tool for evaluating skeletal muscle pathology and tissue engineering approaches to muscle repair and regeneration.

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In Vivo Functional Testing

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