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Quantitative 3D In Silico Modeling (q3DISM) of Cerebral Amyloid-beta Phagocytosis in Rodent Models of Alzheimer's Disease

DOI :

10.3791/54868-v

December 26th, 2016

December 26th, 2016

7,794 Views

1Zilkha Neurogenetic Institute, University of Southern California (USC)

We developed a methodology for quantitative 3D in silico modeling (q3DISM) of cerebral amyloid-β (Aβ) phagocytosis by mononuclear phagocytes in rodent models of Alzheimer's disease. This method can be generalized for the quantitation of virtually any phagocytic event in vivo.

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Keywords Quantitative 3D In Silico Modeling

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