Seeding the Microfluidic Chip with Primary Peritoneal Mesothelial Cells
6:08
Ovarian Cancer Spheroid Formation and Co-culture
8:09
Perfusion Platform Assembly and Co-culture
9:16
Results: Ovarian Cancer Spheroid Behavior in a 3D Peritoneal Microfluidic Device
10:09
Conclusion
Transcript
The overall goal of this procedure is to create a dynamic microfluidic-based co-culture platform to emulate the intraperitoneal environment with the cellular and mechanical components where ovarian cancer metastasis occurs. By using this micro for
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Para estudiar la progresión del tumor de ovario en un modelo fisiológicamente relevante, esferoides multicelulares se cultivaron en un microdispositivo bajo un flujo de fluido simulado. Este modelo 3D dinámico emula el medio ambiente intraperitoneal con los componentes celulares y mecánicas donde se produce la metástasis del cáncer de ovario.