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Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

8.7K Views

09:38 min

August 11th, 2017

DOI :

10.3791/55967-v

August 11th, 2017


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Keywords Lung Adenocarcinoma

Chapters in this video

0:05

Title

0:30

Determining Initial Gefitnib Concentration Using the 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenylterazolium Bromide (MTT) Assay

2:15

Continuous Stepwise Dose-escalation of Gefitnib Treatment of PC-9 Cells

3:31

Determine Initial Concentration of PHA665752 Using the MTT Assay

6:37

Results: Two-step Dose-escalation Procedure to Establish Dual Resistance to EGFT-TKI and MET-TKI

8:21

Conclusion

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