March 30th, 2018
•Mantle cell lymphoma (MCL) is a difficult to treat B cell disorder and it is equally difficult to establish a xenograft mouse model of primary MCL to study and develop therapeutics. Here, we describe the successful establishment of MCL xenografts in mice to help understand its underlying biology.
Related Videos
Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies Video (Video) | JoVE
Isolation of Circulating Tumor Cells in an Orthotopic Mouse Model of Colorectal Cancer Video (Video) | JoVE
A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells Video (Video) | JoVE
Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis Video (Video) | JoVE
A Melanoma Patient-Derived Xenograft Model Video (Video) | JoVE
A Human Peripheral Blood Mononuclear Cell PBMC Engrafted Humanized Xenograft Model for Translational Immuno-oncology I-O Research Video (Video) | JoVE
Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines Video (Video) | JoVE
Generation of a Liver Orthotopic Human Uveal Melanoma Xenograft Platform in Immunodeficient Mice Video (Video) | JoVE
A Mouse Model to Investigate the Role of Cancer-Associated Fibroblasts in Tumor Growth Video (Video) | JoVE
A Murine Ommaya Xenograft Model to Study Direct-Targeted Therapy of Leptomeningeal Disease Video (Video) | JoVE
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved