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Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy

DOI :

10.3791/56284-v

9:24 min

November 29th, 2017

November 29th, 2017

7,197 Views

1EPSRC Proteus Hub, MRC Centre of Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, 2School of Chemistry, EaStChem, University of Edinburgh

This technique describes an efficient screening process for evaluating bacteria-specific optical imaging agents within ex vivo human lung tissue, by fibered confocal fluorescence microscopy for the rapid identification of small molecule chemical probe-candidates with translatable potential.

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Keywords Optical Imaging

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