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Homochronic Transplantation of Interneuron Precursors into Early Postnatal Mouse Brains

DOI :

10.3791/57723-v

June 8th, 2018

June 8th, 2018

7,586 Views

1Kavli Institute for Systems Neuroscience and Centre for Neural Computation, Norwegian University of Science and Technology, 2Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health

Challenging young neurons in new brain regions can reveal important insights into how the environment sculpts neuronal fate and maturation. This protocol describes a procedure to harvest interneuron precursors from specific brain regions and transplant them either homotopically or heterotopically into the brain of postnatal pups.

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Homochronic Transplantation

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