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Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

DOI :

10.3791/51298-v

June 4th, 2014

June 4th, 2014

14,838 Views

1Department of Molecular Genetics and Microbiology, Duke University Medical Center, 2Departments of Neurobiology and Cell Biology, Duke Institute for Brain Sciences, Duke University Medical Center

Neural progenitor mitosis is a critical parameter of neurogenesis. Much of our understanding of neural progenitor mitosis is based on analysis of fixed tissue. Live imaging in embryonic brain slices is a versatile technique to assess mitosis with high temporal and spatial resolution in a controlled environment.

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Live Imaging

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