JoVE Logo
Faculty Resource Center

Sign In

Intravenous and Intra-amniotic In Utero Transplantation in the Murine Model

DOI :

10.3791/58047-v

October 9th, 2018

October 9th, 2018

8,998 Views

1Division of General, Thoracic, and Fetal Surgery, Center for Fetal Research, Children's Hospital of Philadelphia, 2Division of Plastic Reconstructive Surgery, Center for Fetal Research, Children's Hospital of Philadelphia

We describe a protocol for performing an in utero transplantation (IUT) through intravenous and intra-amniotic routes of injection in the murine model. This protocol can be used to introduce cells, viral vectors, and other substances into the unique immune-tolerant fetal environment.

-- Views

Related Videos

article

Author Spotlight: Advancing Lens Biomechanics Research Through a Novel Protocol for Imaging Complex Interdigitations and Protein Staining

article

Author Spotlight: Effect of Left Atrial Ligation on Avian Embryonic Hearts and HLHS Implications

article

Author Spotlight: Studying hiPSC-Derived Endothelial Cells Cultured Under Fluidic-Mediated Mechanical Stimulation

article

Author Spotlight: Optimizing iPSC Differentiation for Efficient Production to Generate Kidney Organoids

article

Author Spotlight: Investigating mRNA Spatial Distribution in Drosophila Muscle Tissue

article

Author Spotlight: Advancing Research Through Single Cell Sequencing and Spatial Histology in Placental Tissues

article

Author Spotlight: A Live Cell Imaging Technique to Study Calcium Signaling and Acrosome Exocytosis in Mouse Sperm

article

Author Spotlight: Exploring Retinal Regeneration Mechanisms in the Xenopus Frog

article

Author Spotlight: Understanding Dynamic Cellular Behaviors in Adult Mouse Dental Tissue Renewal and Repairment

article

Author Spotlight: Manipulating Signaling in Zebrafish Embryos to Decode Cell Fate Decisions

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved