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Chronic Sleep Deprivation in Mouse Pups by Means of Gentle Handling

DOI :

10.3791/58150-v

October 11th, 2018

October 11th, 2018

9,415 Views

1Section on Neuroadaptation and Protein Metabolism, National Institute of Mental Health, National Institutes of Health

We describe a sleep deprivation technique known as gentle handling where investigators gently prod mice any time sleep behavior is observed. This method is a powerful tool that allows researchers to study the effects that chronic sleep restriction throughout development can have on future brain physiology and behavior.

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