May 16th, 2019
•The challenge of epilepsy research is to develop novel treatments for patients where classical therapy is inadequate. Using a new protocol—with the help of an implantable drug delivery system—we are able to control seizures in anesthetized mice by the electrophoretic delivery of GABA into the epileptic focus.
Related Videos
GABA-activated Single-channel and Tonic Currents in Rat Brain Slices
Efficient Gene Delivery into Multiple CNS Territories Using In Utero Electroporation
Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System
Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
Lineage-reprogramming of Pericyte-derived Cells of the Adult Human Brain into Induced Neurons
Mouse Microsurgery Infusion Technique for Targeted Substance Delivery into the CNS via the Internal Carotid Artery
Subpial Adeno-associated Virus 9 (AAV9) Vector Delivery in Adult Mice
Whole-cell Currents Induced by Puff Application of GABA in Brain Slices
Quantitative Cell Biology of Neurodegeneration in Drosophila Through Unbiased Analysis of Fluorescently Tagged Proteins Using ImageJ
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved