JoVE Logo
Faculty Resource Center

Sign In

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

DOI :

10.3791/60292-v

8:05 min

November 8th, 2019

November 8th, 2019

6,774 Views

1Department of Microsurgery, Jesús Usón Minimally Invasive Surgery Centre, 2Stem Cell Therapy Unit, Jesús Usón Minimally Invasive Surgery Centre, 3Animal Modelling Unit, Jesús Usón Minimally Invasive Surgery Centre

Here, we describe a pre-clinical animal model for studying the pathophysiology of ischemia-reperfusion injury in reconstructive microsurgery. This free skin flap model based on the superficial caudal epigastric vessels in the rat may also allow for the evaluation of different therapies and compounds to counteract ischemia-reperfusion injury-related damage.

Tags

Ischemia reperfusion Injury

-- Views

Related Videos

article

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury

article

In situ Transverse Rectus Abdominis Myocutaneous Flap: A Rat Model of Myocutaneous Ischemia Reperfusion Injury

article

Ischemia-reperfusion Model of Acute Kidney Injury and Post Injury Fibrosis in Mice

article

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery

article

Induction and Assessment of Ischemia-reperfusion Injury in Langendorff-perfused Rat Hearts

article

Murine Model of Intestinal Ischemia-reperfusion Injury

article

A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure

article

Inducing Ischemia-reperfusion Injury in the Mouse Ear Skin for Intravital Multiphoton Imaging of Immune Responses

article

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

article

Modified Heterotopic Hindlimb Osteomyocutaneous Flap Model in the Rat for Translational Vascularized Composite Allotransplantation Research

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved