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An In Vitro Hemodynamic Loop Model to Investigate the Hemocytocompatibility and Host Cell Activation of Vascular Medical Devices

DOI :

10.3791/61570-v

8:44 min

August 21st, 2020

August 21st, 2020

6,265 Views

1Department of Cardiothoracic Surgery, Otto-von-Guericke-University, 2Department of Mechanical Engineering, Institute for Materials and Joining Technology, Otto-von-Guericke-University, 3Institute of Clinical Chemistry and Pathobiochemistry, Otto-von-Guericke-University, 4Division of Cardiology and Angiology, Department of Internal Medicine, Otto-von-Guericke-University

Presented here is a protocol for a standardized in vitro hemodynamic loop model. This model allows to test the hemocompatibility of perfusion tubes or vascular stents to be in accordance with ISO (International Organization for Standardization) standard 10993-4.

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Hemodynamic Loop Model

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