Preparation of MSCs and Injectable Gelatin Hydrogels
3:38
In Situ MSC-loading and Three-dimensional in Vitro Culture
4:29
Induction of Myocardial Infarction in Mice
5:44
Intramyocardial Transplantation of MSC-loading GH Hydrogels
6:37
Results: Improving Stem Cell Retention and Engraftment with Injectable Hydrogels
8:31
Conclusion
Transcript
This method can help address key issues in current exacerbated cardiac therapy, such as low applicability to low retention and survival of transplanted cells in infarcted hearts. To address this issue, this method can provide a reliable technique
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Stem cell-based therapy has emerged as an efficient strategy to repair injured cardiac tissues after myocardial infarction. We provide an optimal in vivo application for stem cell transplantation using gelatin hydrogels that are able to be enzymatically cross-linked.