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Ultrasound-guided Transthoracic Intramyocardial Injection in Mice

DOI :

10.3791/51566-v

August 5th, 2014

August 5th, 2014

14,178 Views

1Department of Cardiology, Boston Children's Hospital, 2Harvard Stem Cell Institute, Harvard University

Echocardiography-guided percutaneous intramyocardial injection represents an efficient, reliable, and targetable modality for the delivery of gene transfer agents or cells into the murine heart. Following the steps outlined in this protocol, the operator can quickly become competent in this versatile, minimally invasive technique.

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Ultrasound guided Transthoracic Intramyocardial Injection

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