We show that a three-chamber choice task developed for rodents can be adapted to assess the acquisition and reversal of visual discrimination learning in zebrafish. Our behavioral chamber is designed to assess cognitive performance. Once acquired,
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We present a behavioral chamber designed to assess cognitive performance. We provide data showing that once acquired, zebrafish remember the task 8 weeks later. We also show that hyperglycemic zebrafish have altered cognitive performance, indicating that this paradigm is applicable to studies assessing cognition and memory.