Generation and Expansion of Human Cardiomyocytes from Patient Peripheral Blood Mononuclear Cells

3.8K Views

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05:38 min

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February 12th, 2021

DOI :

10.3791/62206-v

February 12th, 2021

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3,809 Views

Shiqiao Ye¹^,², Xiaoping Wan³, Juan Su¹^,², Akshar Patel¹^,²^,⁴, Blake Justis¹^,²^,⁵, Isabelle Deschênes³, Ming-Tao Zhao¹^,²^,⁵^,⁶

¹Center for Cardiovascular Research, The Abigail Wexner Research Institute, Nationwide Children’s Hospital, ²The Heart Center, Nationwide Children’s Hospital, ³Department of Physiology and Cell Biology, The Ohio State University College of Medicine, ⁴Department of Anatomy, The Ohio State University College of Medicine, ⁵MCDB Graduate Program, The Ohio State University, ⁶Department of Pediatrics, The Ohio State University College of Medicine

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Summary

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Cardiomyocyte Generation

Peripheral Blood Mononuclear Cells

IPSC Reprogramming

Cardiovascular Disease Modeling

Cardiac Toxicity Testing

Differentiation Protocol

Cardiomyocyte Differentiation Media

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