Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence

DOI :

10.3791/63095-v

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14:55 min

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March 5th, 2022

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3,625 Views

Alyson Nguyen^1*, Keith Battle^2,3*, Sunita S. Paudel^2,3*, Ningyong Xu², Jessica Bell³, Linn Ayers³, Cassandra Chapman⁴, Ajay P. Singh⁵, Srinivas Palanki⁶, Thomas Rich^3,7, Diego F. Alvarez⁸, Troy Stevens^2,3, Dhananjay T. Tambe^3,4,7

¹Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama, ²Department of Physiology and Cell Biology, College of Medicine, University of South Alabama, ³Center for Lung Biology, College of Medicine, University of South Alabama, ⁴William B. Burnsed Jr. Mechanical, Aerospace, and Biomedical Engineering Department, College of Engineering, University of South Alabama, ⁵Mitchell Cancer Institute, College of Medicine, University of South Alabama, ⁶Department of Chemical and Biomedical Engineering, West Virginia University, ⁷Department of Pharmacology, College of Medicine, University of South Alabama, ⁸Department of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University

Chapters

The Integrative Toolkit to Analyze Cellular Signals (iTACS) platform automates the process of simultaneously measuring a wide variety of chemical and mechanical signals in adherent cells. iTACS is designed to facilitate community-driven development and enable researchers to use all platform features regardless of their educational background.

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