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Using a Cyclic Ion Mobility Spectrometer for Tandem Ion Mobility Experiments

DOI :

10.3791/63451-v

January 20th, 2022

January 20th, 2022

3,673 Views

1INRAE, UR BIA, F-44316 Nantes, France, 2INRAE, BIBS Facility, F-44316 Nantes, France

Ion mobility spectrometry (IMS) is an interesting complement to mass spectrometry for the characterization of biomolecules, notably because it is sensitive to isomerism. This protocol describes a tandem IMS (IMS/IMS) experiment, which allows the isolation of a molecule and the generation of the mobility profiles of its fragments.

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Keywords Cyclic Ion Mobility Spectrometer

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