Experiment Group: Cecal Ligation and Perforation (CLP)
2:35
Transdermal GFR Device Setup
3:49
FITC-Sinistrin Preparation, Injection, and Transdermal GFR Recording
4:43
GFR Measurement
5:47
Results: Analysis of GFR Using Transdermal GFR Device
7:02
Conclusion
Transcript
TGFR offers a real-time assessment of kidney functions. Compared to traditional markers, TGFR can monitor changes in kidney function in the same animals multiple times. Additionally, the technique does not require any blood or urine collection.
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Glomerular filtration rate (GFR) is the ideal marker for assessing kidney function. However, the standard measurement method using inulin injection with serial blood and urine analysis is impractical. This article delineates a practical method to measure GFR transdermally in piglets.