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Open-Source Real-Time Closed-Loop Electrical Threshold Tracking for Translational Pain Research

DOI :

10.3791/64898-v

10:28 min

April 21st, 2023

April 21st, 2023

632 Views

1Anaesthesia, Pain, and Critical Care Sciences, School of Physiology, Pharmacology, & Neuroscience, University of Bristol, 2Eli Lilly and Company, 3Department of Computer Science, University of Bristol, 4Department of Aerospace Engineering, University of Bristol, 5Research Computing, University of Bristol

APTrack is a software plugin developed for the Open Ephys platform that enables real-time data visualization and the closed-loop electrical threshold tracking of neuronal action potentials. We have successfully used this in microneurography for human C-fiber nociceptors and mouse C-fiber and Aδ-fiber nociceptors.

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