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Interview: Bioreactors and Surfaced-Modified 3D-Scaffolds for Stem Cell Research

DOI :

10.3791/792-v

May 21st, 2008

May 21st, 2008

8,192 Views

1Institute for Biological Interfaces, Karlsruhe Institute of Technology

In the past many in vitro culture systems -- mainly monolayer cultures -- often suffered from the disadvantage that differentiated primary cells had a relatively short life-span and de-differentiated during culture. As a consequence, most of their organ-specific functions were lost rapidly. Thus, in order to reproduce better conditions for these cells in vitro, modifications and adaptations have been made to conventional monolayer cultures.

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Bioreactors

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