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Functional overlap of GATA-1 and GATA-2 in primitive hematopoietic development.
Blood Jan, 2004 | Pubmed ID: 14504093
The zinc-finger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages.
Genes & development Feb, 2002 | Pubmed ID: 11825872
The search for the hemangioblast.
Journal of hematotherapy & stem cell research Feb, 2002 | Pubmed ID: 11847000
Hematopoiesis and stem cells: plasticity versus developmental heterogeneity.
Nature immunology Apr, 2002 | Pubmed ID: 11919568
Interaction between FOG-1 and the corepressor C-terminal binding protein is dispensable for normal erythropoiesis in vivo.
Molecular and cellular biology May, 2002 | Pubmed ID: 11940669
Distinct domains of the GATA-1 cofactor FOG-1 differentially influence erythroid versus megakaryocytic maturation.
Molecular and cellular biology Jun, 2002 | Pubmed ID: 12024038
Transcriptional regulation of erythropoiesis: an affair involving multiple partners.
Oncogene May, 2002 | Pubmed ID: 12032775
Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo.
The Journal of experimental medicine Jun, 2002 | Pubmed ID: 12045237
The use of altered specificity mutants to probe specific protein-protein interactions involved in the activation of GATA-1 target genes.
Methods (San Diego, Calif.) Jan, 2002 | Pubmed ID: 12054907
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2002 | Pubmed ID: 12077323
Stem-cell competition.
Nature Jul, 2002 | Pubmed ID: 12097889
X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction.
Blood Sep, 2002 | Pubmed ID: 12200364
Dysregulation of protein modification by ISG15 results in brain cell injury.
Genes & development Sep, 2002 | Pubmed ID: 12208842
Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2.
Development (Cambridge, England) Oct, 2002 | Pubmed ID: 12223418
The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1.
Blood Oct, 2002 | Pubmed ID: 12239153
Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo.
Blood Jan, 2003 | Pubmed ID: 12393529
The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival.
Development (Cambridge, England) Jan, 2003 | Pubmed ID: 12441305
Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5.
Cancer cell Nov, 2002 | Pubmed ID: 12450796
Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation.
Immunity Jan, 2003 | Pubmed ID: 12530980
Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene.
Nature Jan, 2003 | Pubmed ID: 12540851
GATA-1 as a regulator of mast cell differentiation revealed by the phenotype of the GATA-1low mouse mutant.
The Journal of experimental medicine Feb, 2003 | Pubmed ID: 12566412
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.
Nature Jul, 2003 | Pubmed ID: 12891360
Combinatorial interactions of serpent, lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2003 | Pubmed ID: 14504400
Endothelial lineage-mediated loss of the GATA cofactor Friend of GATA 1 impairs cardiac development.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2003 | Pubmed ID: 14614148
Priming the hematopoietic pump.
Immunity Nov, 2003 | Pubmed ID: 14614848
Coregulator-dependent facilitation of chromatin occupancy by GATA-1.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2004 | Pubmed ID: 14715908
More than blood, a novel gene required for mammalian postimplantation development.
Molecular and cellular biology Feb, 2004 | Pubmed ID: 14729962
The SWI/SNF complex--chromatin and cancer.
Nature reviews. Cancer Feb, 2004 | Pubmed ID: 14964309
Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1.
Molecular and cellular biology Mar, 2004 | Pubmed ID: 14966286
Transforming acidic coiled-coil protein 3 (TACC3) controls friend of GATA-1 (FOG-1) subcellular localization and regulates the association between GATA-1 and FOG-1 during hematopoiesis.
The Journal of biological chemistry May, 2004 | Pubmed ID: 15037632
Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.
Cancer cell Apr, 2004 | Pubmed ID: 15093544
Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1.
Molecular and cellular biology Sep, 2004 | Pubmed ID: 15314159
The zebrafish moonshine gene encodes transcriptional intermediary factor 1gamma, an essential regulator of hematopoiesis.
PLoS biology Aug, 2004 | Pubmed ID: 15314655
Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival.
Genes & development Oct, 2004 | Pubmed ID: 15371326
A critical role for eosinophils in allergic airways remodeling.
Science (New York, N.Y.) Sep, 2004 | Pubmed ID: 15375268
Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells.
Nature Oct, 2004 | Pubmed ID: 15457180
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.
The Journal of experimental medicine Oct, 2004 | Pubmed ID: 15466621
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library.
Genome research Oct, 2004 | Pubmed ID: 15489339
Gene targeting and transgenic strategies for the analysis of hematopoietic development in the mouse.
Methods in molecular medicine , 2005 | Pubmed ID: 15492385
Enforced expression of PU.1 rescues osteoclastogenesis from embryonic stem cells lacking Tal-1.
Stem cells (Dayton, Ohio) , 2005 | Pubmed ID: 15625130
Coregulation of GATA factors by the Friend of GATA (FOG) family of multitype zinc finger proteins.
Seminars in cell & developmental biology Feb, 2005 | Pubmed ID: 15659346
Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development.
Blood May, 2005 | Pubmed ID: 15677556
The placenta is a niche for hematopoietic stem cells.
Developmental cell Mar, 2005 | Pubmed ID: 15737932
Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis.
Blood Jul, 2005 | Pubmed ID: 15811962
Early asymmetry of gene transcription in embryonic human left and right cerebral cortex.
Science (New York, N.Y.) Jun, 2005 | Pubmed ID: 15894532
Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1.
Nature genetics Jun, 2005 | Pubmed ID: 15895080
Stem cells: the road not taken.
Nature Jun, 2005 | Pubmed ID: 15931202
The transcription factor GATA2 regulates differentiation of brown adipocytes.
EMBO reports Sep, 2005 | Pubmed ID: 16082385
Phosphatidylinositol 3-kinase/Akt induced by erythropoietin renders the erythroid differentiation factor GATA-1 competent for TIMP-1 gene transactivation.
Molecular and cellular biology Sep, 2005 | Pubmed ID: 16107690
Placenta as a site for hematopoietic stem cell development.
Experimental hematology Sep, 2005 | Pubmed ID: 16140153
Chipping away at the embryonic stem cell network.
Cell Sep, 2005 | Pubmed ID: 16179251
Specification of astrocytes by bHLH protein SCL in a restricted region of the neural tube.
Nature Nov, 2005 | Pubmed ID: 16292311
Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells.
Current opinion in hematology Jan, 2006 | Pubmed ID: 16319680
Phosphorylation of Gata1 at serine residues 72, 142, and 310 is not essential for hematopoiesis in vivo.
Blood May, 2006 | Pubmed ID: 16391009
Reactions to the Hwang scandal.
Science (New York, N.Y.) Feb, 2006 | Pubmed ID: 16459360
Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2006 | Pubmed ID: 16492768
Characterization of a megakaryocyte-specific enhancer of the key hemopoietic transcription factor GATA1.
The Journal of biological chemistry May, 2006 | Pubmed ID: 16551635
Notch signaling requires GATA-2 to inhibit myelopoiesis from embryonic stem cells and primary hemopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950) May, 2006 | Pubmed ID: 16621992
Rb is dispensable for self-renewal and multilineage differentiation of adult hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2006 | Pubmed ID: 16754850
Unraveling the transcriptional network controlling ES cell pluripotency.
Genome biology , 2006 | Pubmed ID: 16942632
The journey of developing hematopoietic stem cells.
Development (Cambridge, England) Oct, 2006 | Pubmed ID: 16968814
The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor.
Blood Feb, 2007 | Pubmed ID: 17038527
A protein interaction network for pluripotency of embryonic stem cells.
Nature Nov, 2006 | Pubmed ID: 17093407
Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart.
Cell Dec, 2006 | Pubmed ID: 17123591
Gata4 is necessary for normal pulmonary lobar development.
American journal of respiratory cell and molecular biology Apr, 2007 | Pubmed ID: 17142311
Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment.
Cell Jun, 2007 | Pubmed ID: 17574022
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis.
Nature Jun, 2007 | Pubmed ID: 17581586
Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1.
Molecular cell Aug, 2007 | Pubmed ID: 17707228
Immunology: changed destiny.
Nature Sep, 2007 | Pubmed ID: 17898754
ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex.
Cancer cell Dec, 2007 | Pubmed ID: 18068631
Site-directed, virus-free, and inducible RNAi in embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2007 | Pubmed ID: 18093939
A protein roadmap to pluripotency and faithful reprogramming.
Cells, tissues, organs , 2008 | Pubmed ID: 18196921
Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2008 | Pubmed ID: 18245381
Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis.
Genes & development Feb, 2008 | Pubmed ID: 18258751
Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells.
Genes & development Mar, 2008 | Pubmed ID: 18283123
Hematopoiesis: an evolving paradigm for stem cell biology.
Cell Feb, 2008 | Pubmed ID: 18295580
SnapShot: hematopoiesis.
Cell Feb, 2008 | Pubmed ID: 18295585
Antagonism of FOG-1 and GATA factors in fate choice for the mast cell lineage.
The Journal of experimental medicine Mar, 2008 | Pubmed ID: 18299398
PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.
Nature genetics Apr, 2008 | Pubmed ID: 18311137
An extended transcriptional network for pluripotency of embryonic stem cells.
Cell Mar, 2008 | Pubmed ID: 18358816
The emergence of hematopoietic stem cells is initiated in the placental vasculature in the absence of circulation.
Cell stem cell Mar, 2008 | Pubmed ID: 18371450
Targeted disruption of the basic Krüppel-like factor gene (Klf3) reveals a role in adipogenesis.
Molecular and cellular biology Jun, 2008 | Pubmed ID: 18391014
Stem cells down under-ISSCR 2007.
Cell stem cell Sep, 2007 | Pubmed ID: 18399027
Requirement of Nanog dimerization for stem cell self-renewal and pluripotency.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2008 | Pubmed ID: 18436640
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease.
Genes & development Jun, 2008 | Pubmed ID: 18559481
DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2008 | Pubmed ID: 18667698
GATA4 mediates gene repression in the mature mouse small intestine through interactions with friend of GATA (FOG) cofactors.
Developmental biology Oct, 2008 | Pubmed ID: 18692040
Rb and hematopoiesis: stem cells to anemia.
Cell division , 2008 | Pubmed ID: 18775080
Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryos.
Developmental cell Nov, 2008 | Pubmed ID: 18848501
EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency.
Molecular cell Nov, 2008 | Pubmed ID: 19026780
Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Science (New York, N.Y.) Dec, 2008 | Pubmed ID: 19056937
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling.
Nature immunology Jan, 2009 | Pubmed ID: 19060901
Glimpses of the epigenetic landscape.
Cell stem cell Jan, 2009 | Pubmed ID: 19128786
Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis.
Blood Apr, 2009 | Pubmed ID: 19211936
Tandem affinity purification of protein complexes in mouse embryonic stem cells using in vivo biotinylation.
Current protocols in stem cell biology Mar, 2009 | Pubmed ID: 19306258
Use of in vivo biotinylation to study protein-protein and protein-DNA interactions in mouse embryonic stem cells.
Nature protocols , 2009 | Pubmed ID: 19325547
A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal.
Genes & development Apr, 2009 | Pubmed ID: 19339689
Musings on genome medicine: abuse of genetic tests.
Genome medicine , 2009 | Pubmed ID: 19341489
Musings on genome medicine: the Obama effect.
Genome medicine , 2009 | Pubmed ID: 19341501
Musings on genome medicine: genome wide association studies.
Genome medicine , 2009 | Pubmed ID: 19348690
Musings on genome medicine: gene therapy.
Genome medicine , 2009 | Pubmed ID: 19435468
Musings on genome medicine: cancer genetics and the promise of effective treatment.
Genome medicine , 2009 | Pubmed ID: 19439059
Musings on genome medicine: cholesterol and coronary artery disease.
Genome medicine , 2009 | Pubmed ID: 19519958
TEL-AML1 corrupts hematopoietic stem cells to persist in the bone marrow and initiate leukemia.
Cell stem cell Jul, 2009 | Pubmed ID: 19570513
GATA-2 reinforces megakaryocyte development in the absence of GATA-1.
Molecular and cellular biology Sep, 2009 | Pubmed ID: 19620289
Translational isoforms of FOG1 regulate GATA1-interacting complexes.
The Journal of biological chemistry Oct, 2009 | Pubmed ID: 19654328
Developmental and species-divergent globin switching are driven by BCL11A.
Nature Aug, 2009 | Pubmed ID: 19657335
Musings on genome medicine: the Obama effect redux.
Genome medicine , 2009 | Pubmed ID: 19769781
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells.
Cell stem cell Oct, 2009 | Pubmed ID: 19796624
Musings on genome medicine: the slow but inexorable process of medical care reform in the United States.
Genome medicine , 2009 | Pubmed ID: 19822025
Musings on genome medicine: Crohn's disease.
Genome medicine , 2009 | Pubmed ID: 19891793
Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis.
Molecular cell Nov, 2009 | Pubmed ID: 19941827
Musings on genome medicine: enzyme-replacement therapy of the lysosomal storage diseases.
Genome medicine , 2009 | Pubmed ID: 20017892
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.
Cell Dec, 2009 | Pubmed ID: 20064376
Systematic tracking of cell fate changes.
Nature biotechnology Feb, 2010 | Pubmed ID: 20139953
Perturbed hematopoiesis in the Tc1 mouse model of Down syndrome.
Blood Apr, 2010 | Pubmed ID: 20154221
Musings on genome medicine: Hepatitis C.
Genome medicine , 2010 | Pubmed ID: 20193049
miR-125b-2 is a potential oncomiR on human chromosome 21 in megakaryoblastic leukemia.
Genes & development Mar, 2010 | Pubmed ID: 20194440
Advances in the understanding of haemoglobin switching.
British journal of haematology Apr, 2010 | Pubmed ID: 20201948
DNA methylation in adult stem cells: new insights into self-renewal.
Epigenetics : official journal of the DNA Methylation Society Apr, 2010 | Pubmed ID: 20364115
Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.
Genes & development Apr, 2010 | Pubmed ID: 20395365
Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP).
The Journal of biological chemistry Sep, 2010 | Pubmed ID: 20587419
TIF1gamma controls erythroid cell fate by regulating transcription elongation.
Cell Jul, 2010 | Pubmed ID: 20603019
Medicine. Sickle cell disease at 100 years.
Science (New York, N.Y.) Jul, 2010 | Pubmed ID: 20647458
Developmental stage-specific interplay of GATA1 and IGF signaling in fetal megakaryopoiesis and leukemogenesis.
Genes & development Aug, 2010 | Pubmed ID: 20679399
Transcriptional silencing of fetal hemoglobin by BCL11A.
Annals of the New York Academy of Sciences Aug, 2010 | Pubmed ID: 20712774
Training program in cancer and blood diseases: Pediatric Hematology/Oncology Fellowship Program, Children's Hospital Boston/Dana-Farber Cancer Institute.
American journal of hematology Oct, 2010 | Pubmed ID: 20730793
Differential roles of Sall4 isoforms in embryonic stem cell pluripotency.
Molecular and cellular biology Nov, 2010 | Pubmed ID: 20837710
A single cis element maintains repression of the key developmental regulator Gata2.
PLoS genetics Sep, 2010 | Pubmed ID: 20838598
A Myc network accounts for similarities between embryonic stem and cancer cell transcription programs.
Cell Oct, 2010 | Pubmed ID: 20946988
Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation.
Cancer cell Oct, 2010 | Pubmed ID: 20951942
Modifier genes in Mendelian disorders: the example of hemoglobin disorders.
Annals of the New York Academy of Sciences Dec, 2010 | Pubmed ID: 21039591
Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation.
Nature genetics Dec, 2010 | Pubmed ID: 21057501
Networking erythropoiesis.
The Journal of experimental medicine Nov, 2010 | Pubmed ID: 21098097
Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Blood Mar, 2011 | Pubmed ID: 21156846
Update on fetal hemoglobin gene regulation in hemoglobinopathies.
Current opinion in pediatrics Feb, 2011 | Pubmed ID: 21157349
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2011 | Pubmed ID: 21205891
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells.
Cell stem cell Feb, 2011 | Pubmed ID: 21295276
Context-dependent function of "GATA switch" sites in vivo.
Blood May, 2011 | Pubmed ID: 21398579
The erythroid/myeloid lineage fate paradigm takes a new player.
The EMBO journal Mar, 2011 | Pubmed ID: 21407249
Genome Medicine: stem cells, genomics and translational research.
Genome medicine , 2011 | Pubmed ID: 21658298
Chromatin connections to pluripotency and cellular reprogramming.
Cell Jun, 2011 | Pubmed ID: 21663790
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2011 | Pubmed ID: 21788502
MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2011 | Pubmed ID: 21849676
A functional element necessary for fetal hemoglobin silencing.
The New England journal of medicine Sep, 2011 | Pubmed ID: 21879898
Zfp281 functions as a transcriptional repressor for pluripotency of mouse embryonic stem cells.
Stem cells (Dayton, Ohio) Nov, 2011 | Pubmed ID: 21915945
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Science (New York, N.Y.) Nov, 2011 | Pubmed ID: 21998251
Embryonic stem cell-specific signatures in cancer: insights into genomic regulatory networks and implications for medicine.
Genome medicine , 2011 | Pubmed ID: 22126538
Polycomb repressive complex 2 regulates normal development of the mouse heart.
Circulation research Feb, 2012 | Pubmed ID: 22158708
Dnmt3a silences hematopoietic stem cell self-renewal.
Nature genetics Jan, 2012 | Pubmed ID: 22200773
PRC2 directly methylates GATA4 and represses its transcriptional activity.
Genes & development Jan, 2012 | Pubmed ID: 22215809
A human stem cell model of early Alzheimer's disease pathology in Down syndrome.
Science translational medicine Mar, 2012 | Pubmed ID: 22344463
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways.
Science translational medicine Feb, 2012 | Pubmed ID: 22344686
Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains.
Genes & development Feb, 2012 | Pubmed ID: 22345515
MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.
Circulation Mar, 2012 | Pubmed ID: 22371328
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2012 | Pubmed ID: 22396593
MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets.
Genome biology , 2012 | Pubmed ID: 22424423
Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia.
The Journal of clinical investigation Jul, 2012 | Pubmed ID: 22706301
The CACCC-binding protein KLF3/BKLF represses a subset of KLF1/EKLF target genes and is required for proper erythroid maturation in vivo.
Molecular and cellular biology Aug, 2012 | Pubmed ID: 22711990
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium.
Cell Aug, 2012 | Pubmed ID: 22863011
Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders.
Blood Oct, 2012 | Pubmed ID: 22904296
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.
Genes & development Sep, 2012 | Pubmed ID: 22929040
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis.
Developmental cell Oct, 2012 | Pubmed ID: 23041383
Altered hematopoiesis in trisomy 21 as revealed through in vitro differentiation of isogenic human pluripotent cells.
Proceedings of the National Academy of Sciences of the United States of America Oct, 2012 | Pubmed ID: 23045682
TiF1-gamma plays an essential role in murine hematopoiesis and regulates transcriptional elongation of erythroid genes.
Developmental biology Jan, 2013 | Pubmed ID: 23159334
The switch from fetal to adult hemoglobin.
Cold Spring Harbor perspectives in medicine Jan, 2013 | Pubmed ID: 23209159
Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.
Molecular cell Mar, 2013 | Pubmed ID: 23395001
Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis.
Current opinion in genetics & development Jun, 2013 | Pubmed ID: 23477921
ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients.
Genes & development Mar, 2013 | Pubmed ID: 23512661
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2013 | Pubmed ID: 23576758
Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation.
eLife , 2013 | Pubmed ID: 23795291
Delineating the mixed lineage leukemia gene expression network in hematopoietic stem cells.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2013 | Pubmed ID: 23824294
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.
Nature chemical biology Oct, 2013 | Pubmed ID: 23974116
Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire.
Cell stem cell Oct, 2013 | Pubmed ID: 24035353
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Science (New York, N.Y.) Oct, 2013 | Pubmed ID: 24115442
Polycomb repressive complex 2 regulates normal hematopoietic stem cell function in a developmental-stage-specific manner.
Cell stem cell Jan, 2014 | Pubmed ID: 24239285
Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.
Molecular cell Jan, 2014 | Pubmed ID: 24361252
Calpain 2 activation of P-TEFb drives megakaryocyte morphogenesis and is disrupted by leukemogenic GATA1 mutation.
Developmental cell Dec, 2013 | Pubmed ID: 24369834
Analysis of chromatin-state plasticity identifies cell-type-specific regulators of H3K27me3 patterns.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2014 | Pubmed ID: 24395799
Corepressor Rcor1 is essential for murine erythropoiesis.
Blood May, 2014 | Pubmed ID: 24652990
Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation.
The Journal of experimental medicine May, 2014 | Pubmed ID: 24711581
Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors.
Cell Apr, 2014 | Pubmed ID: 24766805
Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells.
The Journal of biological chemistry Aug, 2014 | Pubmed ID: 24907273
TMEM14C is required for erythroid mitochondrial heme metabolism.
The Journal of clinical investigation Oct, 2014 | Pubmed ID: 25157825
Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F.
The Journal of experimental medicine Oct, 2014 | Pubmed ID: 25288396
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production.
Genes & development Dec, 2014 | Pubmed ID: 25395663
A comparative encyclopedia of DNA elements in the mouse genome.
Nature Nov, 2014 | Pubmed ID: 25409824
Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.
Science (New York, N.Y.) Nov, 2014 | Pubmed ID: 25411453
Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2014 | Pubmed ID: 25512523
Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis.
Genome biology , 2014 | Pubmed ID: 25517911
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