Department of Medicine
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Membrane restructuring via ceramide results in enhanced solute efflux.
The Journal of biological chemistry Apr, 2002 | Pubmed ID: 11796726
Sphingomyelinase cleavage of sphingomyelin in pure and mixed lipid membranes. Influence of the physical state of the sphingolipid.
Chemistry and physics of lipids Jan, 2002 | Pubmed ID: 11841822
Sphingomyelinases: enzymology and membrane activity.
FEBS letters Oct, 2002 | Pubmed ID: 12401200
Surfactant effects of chlorpromazine and imipramine on lipid bilayers containing sphingomyelin and cholesterol.
Journal of colloid and interface science Dec, 2002 | Pubmed ID: 12573633
Sphingomyelinase activity causes transbilayer lipid translocation in model and cell membranes.
The Journal of biological chemistry Sep, 2003 | Pubmed ID: 12855704
Genomic microarray analysis reveals distinct locations for the CENP-A binding domains in three human chromosome 13q32 neocentromeres.
Human molecular genetics Oct, 2003 | Pubmed ID: 12928482
Interaction of phospholipases C and sphingomyelinase with liposomes.
Methods in enzymology , 2003 | Pubmed ID: 14610804
Membrane fusion induced by the catalytic activity of a phospholipase C/sphingomyelinase from Listeria monocytogenes.
Biochemistry Mar, 2004 | Pubmed ID: 15035639
Human cytomegalovirus: detection of congenital and perinatal infection in Argentina.
BMC pediatrics Jun, 2004 | Pubmed ID: 15214967
Asymmetric addition of ceramides but not dihydroceramides promotes transbilayer (flip-flop) lipid motion in membranes.
Biophysical journal Jan, 2005 | Pubmed ID: 15465865
Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases.
FEBS letters Jan, 2005 | Pubmed ID: 15620691
Biophysics (and sociology) of ceramides.
Biochemical Society symposium , 2005 | Pubmed ID: 15649141
Different effects of long- and short-chain ceramides on the gel-fluid and lamellar-hexagonal transitions of phospholipids: a calorimetric, NMR, and x-ray diffraction study.
Biophysical journal May, 2005 | Pubmed ID: 15695626
Domain formation in sphingomyelin/cholesterol mixed membranes studied by spin-label electron spin resonance spectroscopy.
Biochemistry Mar, 2005 | Pubmed ID: 15779918
Molecular associations and surface-active properties of short- and long-N-acyl chain ceramides.
Biochimica et biophysica acta Jun, 2005 | Pubmed ID: 15904658
Modulation of PI-specific phospholipase C by membrane curvature and molecular order.
Biochemistry Aug, 2005 | Pubmed ID: 16114896
Detergent-resistant, ceramide-enriched domains in sphingomyelin/ceramide bilayers.
Biophysical journal Feb, 2006 | Pubmed ID: 16284266
Alkanes are not innocuous vehicles for hydrophobic reagents in membrane studies.
Chemistry and physics of lipids Feb, 2006 | Pubmed ID: 16413518
Sphingosine increases the permeability of model and cell membranes.
Biophysical journal Jun, 2006 | Pubmed ID: 16533839
Detergent solubilization of phosphatidylcholine bilayers in the fluid state: influence of the acyl chain structure.
Biochimica et biophysica acta Feb, 2006 | Pubmed ID: 16579963
Independent centromere formation in a capricious, gene-free domain of chromosome 13q21 in Old World monkeys and pigs.
Genome biology , 2006 | Pubmed ID: 17040560
Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids.
Biochimica et biophysica acta Dec, 2006 | Pubmed ID: 17070498
Surface-active properties of the antitumour ether lipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine (edelfosine).
Biochimica et biophysica acta Jul, 2007 | Pubmed ID: 17543274
Leakage-free membrane fusion induced by the hydrolytic activity of PlcHR(2), a novel phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.
Biochimica et biophysica acta Oct, 2007 | Pubmed ID: 17560896
Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres.
Genome biology , 2007 | Pubmed ID: 17651496
Triton X-100 partitioning into sphingomyelin bilayers at subsolubilizing detergent concentrations: effect of lipid phase and a comparison with dipalmitoylphosphatidylcholine.
Biophysical journal Nov, 2007 | Pubmed ID: 17675347
Giant unilamellar vesicles electroformed from native membranes and organic lipid mixtures under physiological conditions.
Biophysical journal Nov, 2007 | Pubmed ID: 17704162
Lower muscle strength gains in older men with type 2 diabetes after resistance training.
Journal of diabetes and its complications Mar-Apr, 2008 | Pubmed ID: 18280441
Membrane organization and ionization behavior of the minor but crucial lipid ceramide-1-phosphate.
Biophysical journal Jun, 2008 | Pubmed ID: 18296489
Cholesterol displacement by ceramide in sphingomyelin-containing liquid-ordered domains, and generation of gel regions in giant lipidic vesicles.
FEBS letters Sep, 2008 | Pubmed ID: 18755187
Ceramide-enriched membrane domains in red blood cells and the mechanism of sphingomyelinase-induced hot-cold hemolysis.
Biochemistry Oct, 2008 | Pubmed ID: 18826261
Effects of ceramide and other simple sphingolipids on membrane lateral structure.
Biochimica et biophysica acta Jan, 2009 | Pubmed ID: 18848519
Phase diagrams of lipid mixtures relevant to the study of membrane rafts.
Biochimica et biophysica acta Nov-Dec, 2008 | Pubmed ID: 18952002
Calcium inhibits diacylglycerol uptake by serum albumin.
Biochimica et biophysica acta Mar, 2009 | Pubmed ID: 19101500
Ceramide-induced transbilayer (flip-flop) lipid movement in membranes.
Methods in molecular biology (Clifton, N.J.) , 2009 | Pubmed ID: 19160667
Phospholipase C and sphingomyelinase activities of the Clostridium perfringens alpha-toxin.
Chemistry and physics of lipids May, 2009 | Pubmed ID: 19428363
Combination of the anti-tumour cell ether lipid edelfosine with sterols abolishes haemolytic side effects of the drug.
Journal of chemical biology Nov, 2008 | Pubmed ID: 19568801
Sphingosine-1-phosphate as an amphipathic metabolite: its properties in aqueous and membrane environments.
Biophysical journal Sep, 2009 | Pubmed ID: 19720028
End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa.
Biochimica et biophysica acta Jan, 2010 | Pubmed ID: 19891956
Coexistence of immiscible mixtures of palmitoylsphingomyelin and palmitoylceramide in monolayers and bilayers.
Biophysical journal Nov, 2009 | Pubmed ID: 19917225
Electroformation of giant unilamellar vesicles from native membranes and organic lipid mixtures for the study of lipid domains under physiological ionic-strength conditions.
Methods in molecular biology (Clifton, N.J.) , 2010 | Pubmed ID: 20013393
Transbilayer (flip-flop) lipid motion and lipid scrambling in membranes.
FEBS letters May, 2010 | Pubmed ID: 20043909
Detergent effects on membranes at subsolubilizing concentrations: transmembrane lipid motion, bilayer permeabilization, and vesicle lysis/reassembly are independent phenomena.
Langmuir : the ACS journal of surfaces and colloids May, 2010 | Pubmed ID: 20170131
A paucity of heterochromatin at functional human neocentromeres.
Epigenetics & chromatin , 2010 | Pubmed ID: 20210998
Quantitation of cholesterol incorporation into extruded lipid bilayers.
Biochimica et biophysica acta Sep, 2010 | Pubmed ID: 20537979
Dihydrosphingomyelin impairs HIV-1 infection by rigidifying liquid-ordered membrane domains.
Chemistry & biology Jul, 2010 | Pubmed ID: 20659689
Cholesterol displaces palmitoylceramide from its tight packing with palmitoylsphingomyelin in the absence of a liquid-disordered phase.
Biophysical journal Aug, 2010 | Pubmed ID: 20712995
Effects of bilayer composition and physical properties on the phospholipase C and sphingomyelinase activities of Clostridium perfringens α-toxin.
Biochimica et biophysica acta Jan, 2011 | Pubmed ID: 20727345
Multiple phospholipid substrates of phospholipase C/sphingomyelinase HR2 from Pseudomonas aeruginosa.
Chemistry and physics of lipids Jan, 2011 | Pubmed ID: 21073866
Imaging the early stages of phospholipase C/sphingomyelinase activity on vesicles containing coexisting ordered-disordered and gel-fluid domains.
Journal of lipid research Apr, 2011 | Pubmed ID: 21252263
Implication of ceramide, ceramide 1-phosphate and sphingosine 1-phosphate in tumorigenesis.
Translational oncogenomics , 2008 | Pubmed ID: 21566746
Unexpected wide substrate specificity of C. perfringens α-toxin phospholipase C.
Biochimica et biophysica acta Oct, 2011 | Pubmed ID: 21704605
Formation of novel CENP-A domains on tandem repetitive DNA and across chromosome breakpoints on human chromosome 8q21 neocentromeres.
Chromosoma Dec, 2011 | Pubmed ID: 21826412
Phospholipases C and sphingomyelinases: Lipids as substrates and modulators of enzyme activity.
Progress in lipid research Jul, 2012 | Pubmed ID: 22504350
Lipid bilayers in the gel phase become saturated by triton X-100 at lower surfactant concentrations than those in the fluid phase.
Biophysical journal Jun, 2012 | Pubmed ID: 22713566
Accumulated bending energy elicits neutral sphingomyelinase activity in human red blood cells.
Biophysical journal May, 2012 | Pubmed ID: 22824271
Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers.
Chemistry and physics of lipids Jan, 2013 | Pubmed ID: 23253877
Detergent solubilization of lipid bilayers: a balance of driving forces.
Trends in biochemical sciences Feb, 2013 | Pubmed ID: 23290685
The onset of Triton X-100 solubilization of sphingomyelin/ceramide bilayers: effects of temperature and composition.
Chemistry and physics of lipids Feb-Mar, 2013 | Pubmed ID: 23453949
In situ synthesis of fluorescent membrane lipids (ceramides) using click chemistry.
Journal of chemical biology Jul, 2012 | Pubmed ID: 23596500
The octamer is the major form of CENP-A nucleosomes at human centromeres.
Nature structural & molecular biology Jun, 2013 | Pubmed ID: 23644596
A topical microemulsion for the prevention of allergic rhinitis symptoms: results of a randomized, controlled, double-blind, parallel group, multicentre, multinational clinical trial (Nares study).
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology , 2013 | Pubmed ID: 23981504
Membrane binding and insertion of the predicted transmembrane domain of human scramblase 1.
Biochimica et biophysica acta Jan, 2014 | Pubmed ID: 24099740
Lipid bilayers containing sphingomyelins and ceramides of varying N-acyl lengths: a glimpse into sphingolipid complexity.
Biochimica et biophysica acta Jan, 2014 | Pubmed ID: 24144542
Lamellar gel (lβ) phases of ternary lipid composition containing ceramide and cholesterol.
Biophysical journal Feb, 2014 | Pubmed ID: 24507602
Histones and DNA compete for binding polyphosphoinositides in bilayers.
Biophysical journal Mar, 2014 | Pubmed ID: 24606933
Membrane binding of human phospholipid scramblase 1 cytoplasmic domain.
Biochimica et biophysica acta Jul, 2014 | Pubmed ID: 24680654
Sphingosine induces the aggregation of imine-containing peroxidized vesicles.
Biochimica et biophysica acta Aug, 2014 | Pubmed ID: 24802275
Membrane permeabilization induced by sphingosine: effect of negatively charged lipids.
Biophysical journal Jun, 2014 | Pubmed ID: 24940775
A cholesterol recognition motif in human phospholipid scramblase 1.
Biophysical journal Sep, 2014 | Pubmed ID: 25229146
Biophysical properties of sphingosine, ceramides and other simple sphingolipids.
Biochemical Society transactions Oct, 2014 | Pubmed ID: 25233422
High-melting lipid mixtures and the origin of detergent-resistant membranes studied with temperature-solubilization diagrams.
Biophysical journal Dec, 2014 | Pubmed ID: 25517149
Biophysical properties of novel 1-deoxy-(dihydro)ceramides occurring in mammalian cells.
Biophysical journal Dec, 2014 | Pubmed ID: 25517151
Fluorescent Polyene Ceramide Analogues as Membrane Probes.
Langmuir : the ACS journal of surfaces and colloids Feb, 2015 | Pubmed ID: 25658138
Histones cause aggregation and fusion of lipid vesicles containing phosphatidylinositol-4-phosphate.
Biophysical journal Feb, 2015 | Pubmed ID: 25692591
Atomic force microscopy characterization of palmitoylceramide and cholesterol effects on phospholipid bilayers: a topographic and nanomechanical study.
Langmuir : the ACS journal of surfaces and colloids Feb, 2015 | Pubmed ID: 25693914
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