Department of Medicine
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The Flt3 internal tandem duplication mutant inhibits the function of transcriptional repressors by blocking interactions with SMRT.
Blood Jun, 2004 | Pubmed ID: 14982881
The theoretical basis of transcriptional therapy of cancer: can it be put into practice?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jun, 2005 | Pubmed ID: 15867201
Derepression in the desert: the third workshop on clinical translation of epigenetics in cancer therapeutics.
Cancer research Jul, 2008 | Pubmed ID: 18593891
BCL6 is critical for the development of a diverse primary B cell repertoire.
The Journal of experimental medicine Jun, 2010 | Pubmed ID: 20498019
EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis.
Blood Dec, 2010 | Pubmed ID: 20736451
Epigenetics in AML.
Best practice & research. Clinical haematology Dec, 2010 | Pubmed ID: 21130408
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia.
The Journal of experimental medicine Oct, 2011 | Pubmed ID: 21911423
SYK inhibition and response prediction in diffuse large B-cell lymphoma.
Blood Dec, 2011 | Pubmed ID: 22025527
The Bcl6-SMRT/NCoR cistrome represses inflammation to attenuate atherosclerosis.
Cell metabolism Apr, 2012 | Pubmed ID: 22465074
Oncogene-mediated alterations in chromatin conformation.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2012 | Pubmed ID: 22615383
Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma.
PloS one , 2012 | Pubmed ID: 22808135
Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jan, 2013 | Pubmed ID: 22893614
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.
Cancer research Feb, 2013 | Pubmed ID: 23066032
Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia.
Cancer discovery Nov, 2012 | Pubmed ID: 23107779
Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression.
Cancer research Feb, 2013 | Pubmed ID: 23233736
Notch activation inhibits AML growth and survival: a potential therapeutic approach.
The Journal of experimental medicine Feb, 2013 | Pubmed ID: 23359069
BCL6 breaks occur at different AID sequence motifs in Ig-BCL6 and non-Ig-BCL6 rearrangements.
Blood May, 2013 | Pubmed ID: 23476051
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation.
Cancer cell May, 2013 | Pubmed ID: 23680150
New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytes.
Current opinion in immunology Jun, 2013 | Pubmed ID: 23725655
Differentiation therapy for IDH1/2 mutant malignancies.
Cell research Aug, 2013 | Pubmed ID: 23732524
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.
Proceedings of the National Academy of Sciences of the United States of America May, 2014 | Pubmed ID: 24821775
Hematopoietic Stem Cell Origin of BRAFV600E Mutations in Hairy Cell Leukemia.
Science translational medicine May, 2014 | Pubmed ID: 24871132
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells.
Oncotarget Jul, 2014 | Pubmed ID: 25026298
Deep sequencing reveals clonal evolution patterns and mutation events associated with relapse in B-cell lymphomas.
Genome biology , 2014 | Pubmed ID: 25123191
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia.
Blood Jan, 2015 | Pubmed ID: 25320243
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