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Stimulation of NADPH oxidase by angiotensin II in human neutrophils is mediated by ERK, p38 MAP-kinase and cytosolic phospholipase A2.
Journal of hypertension Jun, 2005 | Pubmed ID: 15894894
WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells.
Cancer research Dec, 2007 | Pubmed ID: 18056455
The effects of natural antioxidants from tomato extract in treated but uncontrolled hypertensive patients.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy Apr, 2009 | Pubmed ID: 19052855
Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.
Cancer research May, 2009 | Pubmed ID: 19383925
STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells.
Blood Apr, 2010 | Pubmed ID: 20154216
Kit inhibitor APcK110 extends survival in an AML xenograft mouse model.
Investigational new drugs Oct, 2011 | Pubmed ID: 20517635
The synthetic heat shock protein 90 (Hsp90) inhibitor EC141 induces degradation of Bcr-Abl p190 protein and apoptosis of Ph-positive acute lymphoblastic leukemia cells.
Investigational new drugs Dec, 2011 | Pubmed ID: 20533075
STAT-3 activates NF-kappaB in chronic lymphocytic leukemia cells.
Molecular cancer research : MCR Apr, 2011 | Pubmed ID: 21364020
Activation of CD44, a receptor for extracellular matrix components, protects chronic lymphocytic leukemia cells from spontaneous and drug induced apoptosis through MCL-1.
Leukemia & lymphoma Sep, 2011 | Pubmed ID: 21649540
The cytokine midkine and its receptor RPTPζ regulate B cell survival in a pathway induced by CD74.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2012 | Pubmed ID: 22140262
Reciprocal changes in regulatory T cells and Th17 helper cells induced by exercise in patients with chronic lymphocytic leukemia.
Leukemia & lymphoma Sep, 2012 | Pubmed ID: 22242820
Increased CD39 expression on CD4(+) T lymphocytes has clinical and prognostic significance in chronic lymphocytic leukemia.
Annals of hematology Aug, 2012 | Pubmed ID: 22349724
Divergence in CD19-mediated signaling unfolds intraclonal diversity in chronic lymphocytic leukemia, which correlates with disease progression.
Journal of immunology (Baltimore, Md. : 1950) Jan, 2013 | Pubmed ID: 23241880
Personalized medicine in CLL: current status and future perspectives.
Cancer letters Sep, 2014 | Pubmed ID: 23879961
Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.
Blood Jun, 2014 | Pubmed ID: 24778152
STAT3-activated GM-CSFRα translocates to the nucleus and protects CLL cells from apoptosis.
Molecular cancer research : MCR Sep, 2014 | Pubmed ID: 24836891
Cell-specific uptake of mantle cell lymphoma-derived exosomes by malignant and non-malignant B-lymphocytes.
Cancer letters Aug, 2015 | Pubmed ID: 25933830
Metabolism pathways in chronic lymphocytic leukemia.
Leukemia & lymphoma Apr, 2016 | Pubmed ID: 26643954
Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2016 | Pubmed ID: 26699502
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