Pei-Hsun Wu

Department of Chemical and Biomolecular Engineering,
Johns Hopkins Physical Sciences - Oncology Center

Johns Hopkins University

BIOGRAPHY

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PUBLICATIONS

High-throughput ballistic injection nanorheology to measure cell mechanics.

Nature protocols Jan, 2012 | Pubmed ID: 22222790

Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer.

Biophysical journal Jun, 2012 | Pubmed ID: 22735523

The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration.

Scientific reports , 2012 | Pubmed ID: 22761994

Functional interplay between the cell cycle and cell phenotypes.

Integrative biology : quantitative biosciences from nano to macro Mar, 2013 | Pubmed ID: 23319145

High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity.

Analytical chemistry Feb, 2013 | Pubmed ID: 23339603

Dimensional control of cancer cell migration.

Biophysical journal Jan, 2013 | Pubmed ID: 23442847

Simultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolution.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2013 | Pubmed ID: 23538711

Fast and accurate automated cell boundary determination for fluorescence microscopy.

Scientific reports , 2013 | Pubmed ID: 23881180

Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis.

Journal of cellular physiology Mar, 2014 | Pubmed ID: 23996089

Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair.

Biomaterials Dec, 2013 | Pubmed ID: 24041426

Three-dimensional cell migration does not follow a random walk.

Proceedings of the National Academy of Sciences of the United States of America Mar, 2014 | Pubmed ID: 24594603

Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model.

Nature protocols Mar, 2015 | Pubmed ID: 25719270

Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions.

Oncotarget Oct, 2015 | Pubmed ID: 26334095

Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions.

Scientific reports Oct, 2015 | Pubmed ID: 26423227

Local 3D matrix confinement determines division axis through cell shape.

Oncotarget Feb, 2016 | Pubmed ID: 26515603

Collective cancer cell invasion induced by coordinated contractile stresses.

Oncotarget Dec, 2015 | Pubmed ID: 26528856

Evolution of cellular morpho-phenotypes in cancer metastasis.

Scientific reports Dec, 2015 | Pubmed ID: 26675084

A robust nonlinear tissue-component discrimination method for computational pathology.

Laboratory investigation; a journal of technical methods and pathology Apr, 2016 | Pubmed ID: 26779829

Differential vesicular sorting of AMPA and GABAA receptors.

Proceedings of the National Academy of Sciences of the United States of America Feb, 2016 | Pubmed ID: 26839408

Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways.

Cell reports 05, 2016 | Pubmed ID: 27160899

Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes.

Neuron Feb, 2017 | Pubmed ID: 28132831

Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote Metastasis.

Molecular cancer research : MCR Jun, 2017 | Pubmed ID: 28213554

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.

Nature communications May, 2017 | Pubmed ID: 28548090

INSTITUTIONS

Johns Hopkins University

JOVE ARTICLES

Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy

Lijuan He^*,1,2,

Alexandra Sneider^*,1,

Weitong Chen¹,

Michelle Karl¹,

Vishnu Prasath³,

Pei-Hsun Wu^1,2,

Gunnar Mattson³,

Denis Wirtz^1,2,4

¹Department of Chemical and Biomolecular Engineering, Johns Hopkins University,

²Johns Hopkins Physical Sciences - Oncology Center, Johns Hopkins University,

³Department of Biomedical Engineering, Johns Hopkins University,

⁴Departments of Oncology and Pathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine

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Pei-Hsun Wu

Department of Chemical and Biomolecular Engineering,Johns Hopkins Physical Sciences - Oncology Center

Johns Hopkins University

Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy

Department of Chemical and Biomolecular Engineering,
Johns Hopkins Physical Sciences - Oncology Center