Department of Chemical and Biomolecular Engineering,
Johns Hopkins Physical Sciences - Oncology Center
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High-throughput ballistic injection nanorheology to measure cell mechanics.
Nature protocols Jan, 2012 | Pubmed ID: 22222790
Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer.
Biophysical journal Jun, 2012 | Pubmed ID: 22735523
The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration.
Scientific reports , 2012 | Pubmed ID: 22761994
Functional interplay between the cell cycle and cell phenotypes.
Integrative biology : quantitative biosciences from nano to macro Mar, 2013 | Pubmed ID: 23319145
High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity.
Analytical chemistry Feb, 2013 | Pubmed ID: 23339603
Dimensional control of cancer cell migration.
Biophysical journal Jan, 2013 | Pubmed ID: 23442847
Simultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolution.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2013 | Pubmed ID: 23538711
Fast and accurate automated cell boundary determination for fluorescence microscopy.
Scientific reports , 2013 | Pubmed ID: 23881180
Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis.
Journal of cellular physiology Mar, 2014 | Pubmed ID: 23996089
Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair.
Biomaterials Dec, 2013 | Pubmed ID: 24041426
Three-dimensional cell migration does not follow a random walk.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2014 | Pubmed ID: 24594603
Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model.
Nature protocols Mar, 2015 | Pubmed ID: 25719270
Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions.
Oncotarget Oct, 2015 | Pubmed ID: 26334095
Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions.
Scientific reports Oct, 2015 | Pubmed ID: 26423227
Local 3D matrix confinement determines division axis through cell shape.
Oncotarget Feb, 2016 | Pubmed ID: 26515603
Collective cancer cell invasion induced by coordinated contractile stresses.
Oncotarget Dec, 2015 | Pubmed ID: 26528856
Evolution of cellular morpho-phenotypes in cancer metastasis.
Scientific reports Dec, 2015 | Pubmed ID: 26675084
A robust nonlinear tissue-component discrimination method for computational pathology.
Laboratory investigation; a journal of technical methods and pathology Apr, 2016 | Pubmed ID: 26779829
Differential vesicular sorting of AMPA and GABAA receptors.
Proceedings of the National Academy of Sciences of the United States of America Feb, 2016 | Pubmed ID: 26839408
Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways.
Cell reports 05, 2016 | Pubmed ID: 27160899
Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes.
Neuron Feb, 2017 | Pubmed ID: 28132831
Hypoxia Selectively Enhances Integrin α5β1 Receptor Expression in Breast Cancer to Promote Metastasis.
Molecular cancer research : MCR Jun, 2017 | Pubmed ID: 28213554
Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.
Nature communications May, 2017 | Pubmed ID: 28548090
Lijuan He*,1,2,
Alexandra Sneider*,1,
Weitong Chen1,
Michelle Karl1,
Vishnu Prasath3,
Pei-Hsun Wu1,2,
Gunnar Mattson3,
Denis Wirtz1,2,4
1Department of Chemical and Biomolecular Engineering, Johns Hopkins University,
2Johns Hopkins Physical Sciences - Oncology Center, Johns Hopkins University,
3Department of Biomedical Engineering, Johns Hopkins University,
4Departments of Oncology and Pathology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine
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