Immunobiology of Dendritic Cells
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CXCL10 antagonism and plasma sDPPIV correlate with increasing liver disease in chronic HCV genotype 4 infected patients.
Cytokine Aug, 2013 | Pubmed ID: 23664274
The ABCs of viral hepatitis that define biomarker signatures of acute viral hepatitis.
Hepatology (Baltimore, Md.) Apr, 2014 | Pubmed ID: 24500966
Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli.
Immunity Mar, 2014 | Pubmed ID: 24656047
Apolipoprotein H expression is associated with IL28B genotype and viral clearance in hepatitis C virus infection.
Journal of hepatology Oct, 2014 | Pubmed ID: 24905490
The Milieu Intérieur study - an integrative approach for study of human immunological variance.
Clinical immunology (Orlando, Fla.) Apr, 2015 | Pubmed ID: 25562703
Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping.
Clinical immunology (Orlando, Fla.) Apr, 2015 | Pubmed ID: 25572534
Automated flow cytometric analysis across large numbers of samples and cell types.
Clinical immunology (Orlando, Fla.) Apr, 2015 | Pubmed ID: 25576660
Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy.
PloS one , 2015 | Pubmed ID: 26181438
Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.
eLife Nov, 2015 | Pubmed ID: 26568315
Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study.
PloS one , 2015 | Pubmed ID: 26670100
Protein biomarkers discriminate Leishmania major-infected and non-infected individuals in areas endemic for cutaneous leishmaniasis.
BMC infectious diseases Mar, 2016 | Pubmed ID: 27009263
Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies.
EMBO molecular medicine 06, 2016 | Pubmed ID: 27137491
Efficacy of the Janus kinase 1/2 inhibitor ruxolitinib in the treatment of vasculopathy associated with TMEM173-activating mutations in 3 children.
The Journal of allergy and clinical immunology Dec, 2016 | Pubmed ID: 27554814
Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses.
Cell reports Sep, 2016 | Pubmed ID: 27568558
Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations.
Cell Oct, 2016 | Pubmed ID: 27768888
Ultrasensitive HIV-1 p24 Assay Detects Single Infected Cells and Differences in Reservoir Induction by Latency Reversal Agents.
Journal of virology 03, 2017 | Pubmed ID: 28077644
Detection of interferon alpha protein reveals differential levels and cellular sources in disease.
The Journal of experimental medicine May, 2017 | Pubmed ID: 28420733
Brief Report: Blockade of TANK-Binding Kinase 1/IKKɛ Inhibits Mutant Stimulator of Interferon Genes (STING)-Mediated Inflammatory Responses in Human Peripheral Blood Mononuclear Cells.
Arthritis & rheumatology (Hoboken, N.J.) 07, 2017 | Pubmed ID: 28426911
Deconvolution of the Response to Bacillus Calmette-Guérin Reveals NF-κB-Induced Cytokines As Autocrine Mediators of Innate Immunity.
Frontiers in immunology , 2017 | Pubmed ID: 28751891
An in vitro diagnostic certified point of care single nucleotide test for IL28B polymorphisms.
PloS one , 2017 | Pubmed ID: 28877177
Myogenic Progenitor Cells Exhibit Type I Interferon-Driven Proangiogenic Properties and Molecular Signature During Juvenile Dermatomyositis.
Arthritis & rheumatology (Hoboken, N.J.) Jan, 2018 | Pubmed ID: 28941175
Standardized whole blood stimulation improves immunomonitoring of induced immune responses in multi-center study.
Clinical immunology (Orlando, Fla.) 10, 2017 | Pubmed ID: 28943400
Type I interferon-mediated autoinflammation due to DNase II deficiency.
Nature communications Dec, 2017 | Pubmed ID: 29259162
Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2018 | Pubmed ID: 29282317
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.
Nature immunology Mar, 2018 | Pubmed ID: 29476184
T-cell biomarkers for diagnosis of tuberculosis: candidate evaluation by a simple whole blood assay for clinical translation.
The European respiratory journal Mar, 2018 | Pubmed ID: 29567725
Development and clinical validation of the Genedrive point-of-care test for qualitative detection of hepatitis C virus.
Gut Apr, 2018 | Pubmed ID: 29615488
Milieu intérieur: Defining the boundaries of a healthy immune response for improved vaccination strategies.
Human vaccines & immunotherapeutics May, 2018 | Pubmed ID: 29714672
Publisher Correction: Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors.
Nature immunology Jun, 2018 | Pubmed ID: 29725081
JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis.
Brain : a journal of neurology Jun, 2018 | Pubmed ID: 29741608
Development of a Bead-Based Multiplex Assay for the Analysis of the Serological Response against the Six Pathogens HAV, HBV, HCV, CMV, T. gondii, and H. pylori.
High-throughput Oct, 2017 | Pubmed ID: 29855458
Study of the Humoral Immune Response towards HCV Genotype 4 Using a Bead-Based Multiplex Serological Assay.
High-throughput Oct, 2017 | Pubmed ID: 29855459
Comment on: 'Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors' by Giannelou : mutations in result in a constitutive activation of type I interferon signalling.
Annals of the rheumatic diseases Jun, 2018 | Pubmed ID: 29858171
Alba Llibre*,1,2,
Vincent Bondet*,1,2,
Mathieu P. Rodero3,
David Hunt4,
Yanick J. Crow3,5,
Darragh Duffy1,2
1Immunobiology of Dendritic Cells, Institut Pasteur,
2, INSERM U1223,
3Laboratory of Neurogenetics and Neuroinflammation, INSERM UMR1163, Institut Imagine,
4MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh,
5Manchester Centre for Genomic Medicine, University of Manchester
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