Jessica S. Blackburn

RNA interference inhibition of matrix metalloproteinase-1 prevents melanoma metastasis by reducing tumor collagenase activity and angiogenesis.

Matrix metalloproteinase-1 and thrombin differentially activate gene expression in endothelial cells via PAR-1 and promote angiogenesis.

Wild-type versus mutant MMP-8 in melanoma: 'when you come to a fork in the road, take it'.

Matrix metalloproteinase and G protein coupled receptors: co-conspirators in the pathogenesis of autoimmune disease and cancer.

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.

aMAZe-ing tools for mosaic analysis in zebrafish.

Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA).

High-throughput imaging of adult fluorescent zebrafish with an LED fluorescence macroscope.

Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish.

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish.

TOX Regulates Growth, DNA Repair, and Genomic Instability in T-cell Acute Lymphoblastic Leukemia.

Targeting phosphatases of regenerating liver (PRLs) in cancer.

Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo.

A screen of FDA-approved drugs identifies inhibitors of protein tyrosine phosphatase 4A3 (PTP4A3 or PRL-3).

Long-read sequencing of the zebrafish genome reorganizes genomic architecture.

Phosphatase and Pseudo-Phosphatase Functions of Phosphatase of Regenerating Liver 3 (PRL-3) Are Insensitive to Divalent Metals In Vitro.

Zebrafish drug screening identifies Erlotinib as an inhibitor of Wnt/β-catenin signaling and self-renewal in T-cell acute lymphoblastic leukemia.

Examining Phosphatases Through Immunofluorescent Microscopy.