Center for Lung Biology,
Department of Pharmacology,
College of Medicine,
Center for Lung Biology, College of Medicine,
Department of Pharmacology, College of Medicine
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Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells.
American journal of physiology. Cell physiology Jan, 2007 | Pubmed ID: 16899551
Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signaling.
The Journal of general physiology Apr, 2008 | Pubmed ID: 18347080
Receptor reserve reflects differential intrinsic efficacy associated with opioid diastereomers.
Pharmacology, biochemistry, and behavior May, 2009 | Pubmed ID: 19463265
Quantitative modeling of GRK-mediated beta2AR regulation.
PLoS computational biology Jan, 2010 | Pubmed ID: 20098494
PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblasts.
The Journal of biological chemistry Apr, 2011 | Pubmed ID: 21288894
A2B adenosine receptors inhibit superoxide production from mitochondrial complex I in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxin.
British journal of pharmacology Jul, 2011 | Pubmed ID: 21366548
Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP.
Molecular pharmacology Aug, 2011 | Pubmed ID: 21551375
All preconditioning-related G protein-coupled receptors can be demonstrated in the rabbit cardiomyocyte.
Journal of cardiovascular pharmacology and therapeutics Jun, 2012 | Pubmed ID: 21828281
Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue.
Journal of biophotonics Jan, 2012 | Pubmed ID: 21987373
Assessment of cellular mechanisms contributing to cAMP compartmentalization in pulmonary microvascular endothelial cells.
American journal of physiology. Cell physiology Mar, 2012 | Pubmed ID: 22116306
A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Sep, 2012 | Pubmed ID: 22649031
Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells.
PloS one , 2012 | Pubmed ID: 22876290
Feedback regulation of cone cyclic nucleotide channels by phosphoinositides. Focus on "CNGA3 achromatopsia-associated mutation potentiates the phosphoinositide sensitivity of cone photoreceptor CNG channels by altering intersubunit interactions".
American journal of physiology. Cell physiology Jul, 2013 | Pubmed ID: 23677796
Hyperspectral imaging of FRET-based cGMP probes.
Methods in molecular biology (Clifton, N.J.) , 2013 | Pubmed ID: 23709027
An approach for characterizing and comparing hyperspectral microscopy systems.
Sensors (Basel, Switzerland) Jul, 2013 | Pubmed ID: 23877125
Assessing FRET using spectral techniques.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Oct, 2013 | Pubmed ID: 23929684
Thin-film tunable filters for hyperspectral fluorescence microscopy.
Journal of biomedical optics Jan, 2014 | Pubmed ID: 24077519
Can we decipher the information content contained within cyclic nucleotide signals?
The Journal of general physiology Jan, 2014 | Pubmed ID: 24378904
Excitation-scanning hyperspectral imaging microscope.
Journal of biomedical optics Apr, 2014 | Pubmed ID: 24727909
β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent.
The Journal of biological chemistry Aug, 2014 | Pubmed ID: 24973219
FRET: signals hidden within the noise.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Nov, 2014 | Pubmed ID: 25241962
Sodium entry through endothelial store-operated calcium entry channels: regulation by Orai1.
American journal of physiology. Cell physiology Feb, 2015 | Pubmed ID: 25428882
Automated image analysis of FRET signals for subcellular cAMP quantification.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25783877
Channel-based reporters for cAMP detection.
Methods in molecular biology (Clifton, N.J.) , 2015 | Pubmed ID: 25783878
Estimating the magnitude of near-membrane PDE4 activity in living cells.
American journal of physiology. Cell physiology Sep, 2015 | Pubmed ID: 26201952
Overcoming limitations of FRET measurements.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Apr, 2016 | Pubmed ID: 27101317
Hyperspectral imaging fluorescence excitation scanning for colon cancer detection.
Journal of biomedical optics 10, 2016 | Pubmed ID: 27792808
A theoretical-experimental methodology for assessing the sensitivity of biomedical spectral imaging platforms, assays, and analysis methods.
Journal of biophotonics Jan, 2018 | Pubmed ID: 28485093
Human ASIC1a mediates stronger acid-induced responses as compared with mouse ASIC1a.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jul, 2018 | Pubmed ID: 29447005
Spectral imaging of FRET-based sensors reveals sustained cAMP gradients in three spatial dimensions.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 10, 2018 | Pubmed ID: 30176184
Identifying molecular contributors to autofluorescence of neoplastic and normal colon sections using excitation-scanning hyperspectral imaging.
Journal of biomedical optics 12, 2018 | Pubmed ID: 30592190
Label-free spectroscopic tissue characterization using fluorescence excitation-scanning spectral imaging.
Journal of biophotonics 02, 2020 | Pubmed ID: 31566889
Applications and assessment of an excitation-scanning hyperspectral imaging system.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2018 | Pubmed ID: 31762531
cAMP signaling primes lung endothelial cells to activate caspase-1 during infection.
American journal of physiology. Lung cellular and molecular physiology 05, 2020 | Pubmed ID: 32186399
Development of an endothelial cell-restricted transgenic reporter rat: a resource for physiological studies of vascular biology.
American journal of physiology. Heart and circulatory physiology 08, 2020 | Pubmed ID: 32589443
Milestones in the development and implementation of FRET-based sensors of intracellular signals: A biological perspective of the history of FRET.
Cellular signalling Nov, 2020 | Pubmed ID: 32898611
Excitation-scanning hyperspectral video endoscopy: enhancing the light at the end of the tunnel.
Biomedical optics express Jan, 2021 | Pubmed ID: 33520384
Optical simulations for determining efficacy of new light source designs for excitation-scanning high-speed hyperspectral imaging systems.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2020 | Pubmed ID: 34035556
Comparison of spectral FRET microscopy approaches for single-cell analysis.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2020 | Pubmed ID: 34035557
Design of a modified endoscope illuminator for spectral imaging of colorectal tissues.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2017 | Pubmed ID: 34045780
Hyperspectral imaging microscopy for measurement of localized second messenger signals in single cells.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34045781
A Spherical Mirror-based Illumination System for Fluorescence Excitation-Scanning Hyperspectral Imaging.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34045782
Optimization of Light Transmission through an Excitation-scan Hyperspectral Mirror Array System.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34045783
Optimizing channel selection for excitation-scanning hyperspectral imaging.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34045784
Hyperspectral imaging fluorescence excitation scanning (HIFEX) microscopy for live cell imaging.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34045785
Hyperspectral imaging fluorescence excitation scanning spectral characteristics of remodeled mouse arteries.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34045786
Spectral Illumination System Utilizing Spherical Reflection Optics.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2020 | Pubmed ID: 34045787
Tunable thin-film optical filters for hyperspectral microscopy.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2013 | Pubmed ID: 34045788
Three dimensional measurement of cAMP gradients using hyperspectral confocal microscopy.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2016 | Pubmed ID: 34045789
Comparing Methods for Analysis of Biomedical Hyperspectral Image Data.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2017 | Pubmed ID: 34054187
5D imaging approaches reveal the formation of distinct intracellular cAMP spatial gradients.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2017 | Pubmed ID: 34054188
LED-based endoscopic light source for spectral imaging.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2016 | Pubmed ID: 34054191
Excitation-Scanning Hyperspectral Imaging as a Means to Discriminate Various Tissues Types.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2017 | Pubmed ID: 34092886
Optimization and applications of an excitation-scanning hyperspectral imaging system.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2017 | Pubmed ID: 34092887
Endoscopic hyperspectral imaging: light guide optimization for spectral light source.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2018 | Pubmed ID: 34092888
Colorectal cancer detection by hyperspectral imaging using fluorescence excitation scanning.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2018 | Pubmed ID: 34092889
Demystifying autofluorescence with excitation-scanning hyperspectral imaging.
Proceedings of SPIE--the International Society for Optical Engineering Jan-Feb, 2018 | Pubmed ID: 34092890
Sensitivity analysis of a multibranched light guide for real time hyperspectral imaging systems.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2019 | Pubmed ID: 34092891
Excitation-Scanning Hyperspectral Imaging System for Microscopic and Endoscopic Applications.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2016 | Pubmed ID: 34092892
Excitation-scan Mirror Array System Advancements to Hyperspectral Imaging Applications.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2020 | Pubmed ID: 34121795
Feasibility for detection of autofluorescent signatures in rat organs using a novel excitation-scanning hyperspectral imaging system.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2016 | Pubmed ID: 34131358
Hyperspectral Imaging Fluorescence Excitation Scanning for Detecting Colorectal Cancer: Pilot Study.
Proceedings of SPIE--the International Society for Optical Engineering Feb, 2016 | Pubmed ID: 34429564
Phosphodiesterase 4 mediates interleukin-8-induced heterologous desensitization of the β -adrenergic receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 10, 2021 | Pubmed ID: 34555226
Alyson Nguyen*,1,
Keith Battle*,2,3,
Sunita S. Paudel*,2,3,
Ningyong Xu2,
Jessica Bell3,
Linn Ayers3,
Cassandra Chapman4,
Ajay P. Singh5,
Srinivas Palanki6,
Thomas Rich3,7,
Diego F. Alvarez8,
Troy Stevens2,3,
Dhananjay T. Tambe3,4,7
1Biomedical Sciences, Pat Capps Covey College of Allied Health Professions, University of South Alabama,
2Department of Physiology and Cell Biology, College of Medicine, University of South Alabama,
3Center for Lung Biology, College of Medicine, University of South Alabama,
4William B. Burnsed Jr. Mechanical, Aerospace, and Biomedical Engineering Department, College of Engineering, University of South Alabama,
5Mitchell Cancer Institute, College of Medicine, University of South Alabama,
6Department of Chemical and Biomedical Engineering, West Virginia University,
7Department of Pharmacology, College of Medicine, University of South Alabama,
8Department of Physiology & Pharmacology, College of Osteopathic Medicine, Sam Houston State University
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