Lydia L. Sohn
Graduate Program in Bioengineering
University of California San Francisco and University of California Berkeley
Lydia L. Sohn received her A.B. (Chemistry and Physics, 1988), M.S. (Physics, 1990), and Ph.D. (Physics, 1992) from Harvard University. She was an NSF/NATO postdoc at Delft University of Technology and a postdoc at AT&T Bell Laboratories (1993-1995). Sohn was an Assistant Professor of Physics at Princeton University prior to joining the Mechanical Engineering Dept. at UC Berkeley in 2003. In addition to being Professor of Mechanical Engineering, Sohn is a core-member of the UC San Francisco-UC Berkeley Graduate Program in Bioengineering and is currently serving as a member of the program's Executive Committee . Her work focuses on developing quantitative techniques to probe single cells, as they relate to cancer and stem cells. Sohn has received numerous awards including the NSF CAREER, Army of Research Young Investigator Award, DuPont Young Professor Award, and a Bakar Fellowship. In 2010, Sohn received the prestigious W. M. Keck Foundation Medical Research award to develop a label-free method for screening and sorting rare cells. In 2014, Sohn’s developed label-free method—Node-Pore Sensing (NPS)—was named one of five “Revolutionary Platform Technologies for Advancing Life Sciences Research” in a competition sponsored by 6 major foundations, including the W. M. Keck Foundation, Gordon & Betty Moore Foundation, Kavli Foundation, Burroughs-Wellcome Fund, John Templeton Foundation, and Research Corporation. She is a Fellow of the American Institute for Medical and Biological Engineering and a Chancellor's Professor at UC Berkeley.
Visco-Node-Pore Sensing: A Microfluidic Rheology Platform to Characterize Viscoelastic Properties of Epithelial Cells.
iScience Mar, 2019 | Pubmed ID: 30870780
Node-Pore Sensing for Characterizing Cells and Extracellular Vesicles.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35094328
Mechano-Node-Pore Sensing: A Rapid, Label-Free Platform for Multi-Parameter Single-Cell Viscoelastic Measurements
Simple, Affordable, and Modular Patterning of Cells using DNA
Katelyn A. Cabral1,
David M. Patterson2,
Olivia J. Scheideler1,
Russell Cole3,
Adam R. Abate4,5,6,
David V. Schaffer7,8,
Lydia L. Sohn9,
Zev J. Gartner2,6,10
1Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley,
2Department of Pharmaceutical Chemistry, University of California San Francisco,
3, Scribe Biosciences,
4Department of Bioengineering and Therapeutic Sciences, University of California San Francisco,
5California Institute for Quantitative Biosciences, University of California San Francisco,
6Chan Zuckerberg Biohub, University of California San Francisco,
7Department of Chemical & Biomolecular Engineering, University of California Berkeley,
8Helen Wills Neuroscience Institute, University of California Berkeley,
9Department of Mechanical Engineering, University of California Berkeley,
10Center for Cellular Construction, University of California San Francisco
Patterning the Geometry of Human Embryonic Stem Cell Colonies on Compliant Substrates to Control Tissue-Level Mechanics
Jonathon M. Muncie1,2,
Roberto Falcón-Banchs1,
Johnathon N. Lakins2,
Lydia L. Sohn1,3,
Valerie M. Weaver2,4,5,6
1Graduate Program in Bioengineering, University of California San Francisco and University of California Berkeley,
2Center for Bioengineering and Tissue Regeneration, Department of Surgery, University of California San Francisco,
3Department of Mechanical Engineering, University of California Berkeley,
4Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco,
5UCSF Comprehensive Cancer Center, Helen Diller Family Cancer Research Center, University of California San Francisco,
6Department of Anatomy, Department of Bioengineering and Therapeutic Sciences, and Department of Radiation Oncology, University of California San Francisco
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