Louis Droogmans
Laboratory of Microbiology,
Department of Molecular Biology,
Laboratory of Microbiology, Department of Molecular Biology
Université Libre de Bruxelles
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Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.
The EMBO journal Apr, 2001 | Pubmed ID: 11285217
Upstream stimulatory factors binding to an E box motif in the R region of the bovine leukemia virus long terminal repeat stimulates viral gene expression.
The Journal of biological chemistry Mar, 2002 | Pubmed ID: 11741930
Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase.
Journal of the American Chemical Society Mar, 2003 | Pubmed ID: 12630859
Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.
Nucleic acids research Apr, 2003 | Pubmed ID: 12682365
The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.
Journal of bacteriology May, 2003 | Pubmed ID: 12730187
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase.
Nucleic acids research , 2004 | Pubmed ID: 14739239
Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.
RNA (New York, N.Y.) Aug, 2004 | Pubmed ID: 15247431
A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase.
Journal of the American Chemical Society Jan, 2005 | Pubmed ID: 15643873
The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.
BMC molecular biology Jul, 2006 | Pubmed ID: 16848900
The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).
Nucleic acids research Jun, 2008 | Pubmed ID: 18420655
Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.
Molecular biology and evolution Sep, 2010 | Pubmed ID: 20382657
New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.
Nucleic acids research Oct, 2010 | Pubmed ID: 20525789
Crystallization and preliminary X-ray crystallographic analysis of putative tRNA-modification enzymes from Pyrococcus furiosus and Thermus thermophilus.
Acta crystallographica. Section F, Structural biology and crystallization communications Nov, 2011 | Pubmed ID: 22102250
The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N²-methylguanosine at position 6 in tRNA.
RNA (New York, N.Y.) Apr, 2012 | Pubmed ID: 22337946
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic acids research Jun, 2012 | Pubmed ID: 22362751
Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.
RNA (New York, N.Y.) Aug, 2014 | Pubmed ID: 24951554
Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.
Nucleic acids research Jan, 2016 | Pubmed ID: 26673726
AtaT blocks translation initiation by N-acetylation of the initiator tRNA.
Nature chemical biology 06, 2017 | Pubmed ID: 28369041
Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein.
Biochimica et biophysica acta. Molecular basis of disease 12, 2017 | Pubmed ID: 28888424
Structural and biochemical analysis of the dual-specificity Trm10 enzyme from prompts reconsideration of its catalytic mechanism.
RNA (New York, N.Y.) 08, 2018 | Pubmed ID: 29848639
Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes.
The Journal of biological chemistry 08, 2018 | Pubmed ID: 29880640
Bisubstrate analogues as structural tools to investigate mA methyltransferase active sites.
RNA biology 06, 2019 | Pubmed ID: 30879411
Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.
Nucleic acids research 05, 2019 | Pubmed ID: 30931478
How metal cofactors drive dimer-dodecamer transition of the M42 aminopeptidase TmPep1050 of .
The Journal of biological chemistry Nov, 2019 | Pubmed ID: 31611236
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