Louis Droogmans

Crystal structure of isopentenyl diphosphate:dimethylallyl diphosphate isomerase.

Upstream stimulatory factors binding to an E box motif in the R region of the bovine leukemia virus long terminal repeat stimulates viral gene expression.

Structure and mechanism of action of isopentenylpyrophosphate-dimethylallylpyrophosphate isomerase.

Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures.

The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.

A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase.

Identification of a bifunctional enzyme MnmC involved in the biosynthesis of a hypermodified uridine in the wobble position of tRNA.

A crystallographic investigation of phosphoantigen binding to isopentenyl pyrophosphate/dimethylallyl pyrophosphate isomerase.

The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase.

The YqfN protein of Bacillus subtilis is the tRNA: m1A22 methyltransferase (TrmK).

Biosynthesis of wyosine derivatives in tRNA: an ancient and highly diverse pathway in Archaea.

New archaeal methyltransferases forming 1-methyladenosine or 1-methyladenosine and 1-methylguanosine at position 9 of tRNA.

Crystallization and preliminary X-ray crystallographic analysis of putative tRNA-modification enzymes from Pyrococcus furiosus and Thermus thermophilus.

The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N²-methylguanosine at position 6 in tRNA.

Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.

Characterization of two homologous 2'-O-methyltransferases showing different specificities for their tRNA substrates.

Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue.

AtaT blocks translation initiation by N-acetylation of the initiator tRNA.

Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein.

Structural and biochemical analysis of the dual-specificity Trm10 enzyme from prompts reconsideration of its catalytic mechanism.

Structural insight into the human mitochondrial tRNA purine N1-methyltransferase and ribonuclease P complexes.

Bisubstrate analogues as structural tools to investigate mA methyltransferase active sites.

Structural characterization of B. subtilis m1A22 tRNA methyltransferase TrmK: insights into tRNA recognition.

How metal cofactors drive dimer-dodecamer transition of the M42 aminopeptidase TmPep1050 of .