Alexander Fish

Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.

Homodimerization antagonizes nuclear export of survivin.

A supraphysiological nuclear export signal is required for parvovirus nuclear export.

Ubc9 sumoylation regulates SUMO target discrimination.

Venezuelan equine Encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin alpha/beta that obstructs nuclear pore complex function.

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation.

Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.

Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.

The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.

Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.

Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.

LNA modification of single-stranded DNA oligonucleotides allows subtle gene modification in mismatch-repair-proficient cells.

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

A fragment-like approach to PYCR1 inhibition.