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Oncode Institute and Division of Biochemistry
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Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.
The EMBO journal Jan, 2006 | Pubmed ID: 16407973
Homodimerization antagonizes nuclear export of survivin.
Traffic (Copenhagen, Denmark) Nov, 2007 | Pubmed ID: 17714426
A supraphysiological nuclear export signal is required for parvovirus nuclear export.
Molecular biology of the cell Jun, 2008 | Pubmed ID: 18385513
Ubc9 sumoylation regulates SUMO target discrimination.
Molecular cell Aug, 2008 | Pubmed ID: 18691969
Venezuelan equine Encephalitis virus capsid protein forms a tetrameric complex with CRM1 and importin alpha/beta that obstructs nuclear pore complex function.
Journal of virology May, 2010 | Pubmed ID: 20147401
Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.
Journal of the American Chemical Society Jul, 2010 | Pubmed ID: 20540574
Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation.
EMBO reports Apr, 2011 | Pubmed ID: 21399620
Ubiquitin-specific protease 4 is inhibited by its ubiquitin-like domain.
EMBO reports Apr, 2011 | Pubmed ID: 21415856
Binding of the J-binding protein to DNA containing glucosylated hmU (base J) or 5-hmC: evidence for a rapid conformational change upon DNA binding.
Journal of the American Chemical Society , | Pubmed ID: 22775585
The polybasic insertion in autotaxin α confers specific binding to heparin and cell surface heparan sulfate proteoglycans.
The Journal of biological chemistry , | Pubmed ID: 23150666
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
Journal of cell science Aug, 2013 | Pubmed ID: 23729732
Hoefavidin: A dimeric bacterial avidin with a C-terminal binding tail.
Journal of structural biology Aug, 2015 | Pubmed ID: 26126731
The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.
Acta crystallographica. Section D, Biological crystallography , | Pubmed ID: 26527144
Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.
Molecular cell Feb, 2016 | Pubmed ID: 26895426
LNA modification of single-stranded DNA oligonucleotides allows subtle gene modification in mismatch-repair-proficient cells.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2016 | Pubmed ID: 26951689
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.
Nature cell biology , | Pubmed ID: 29915359
A fragment-like approach to PYCR1 inhibition.
Bioorganic & medicinal chemistry letters 09, 2019 | Pubmed ID: 31362921
The Netherlands Cancer Institute
Misbha Ud Din Ahmad1,
Alexander Fish1,
Jeroen Molenaar1,
Sridhar Sreeramulu2,
Christian Richter2,
Nadide Altincekic2,
Harald Schwalbe2,
Hans Wienk1,
Anastassis Perrakis1
1Oncode Institute and Division of Biochemistry, the Netherlands Cancer Institute,
2Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University
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