Kevin Pacheco-Barrios

Neuromodulation Center and Center for Clinical Research Learning, Harvard Medical School

Affiliated withHarvard Medical School Universidad de Investigación para la Generación y Síntesis de Evidencia en Salud, Universidad San Ignacio de Loyola Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School

Research Area

Neuroscience

Biography

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JoVE Journal Publications

Article Total : 4	Year
Publication title	2022
Publication title	2024
Publication title	2024
Publication title	2025

Other Publications

Article	Year
Optimised transcranial direct current stimulation (tDCS) for fibromyalgia-targeting the endogenous pain control system: a randomised, double-blind, factorial clinical trial protocol. BMJ open\| PubMed ID: 31672712	2019
Brain perfusion during manic episode and at 6-month follow-up period in bipolar disorder patients: Correlation with cognitive functions. Brain and behavior\| PubMed ID: 32356600	2020
Motor Cortex Reorganization in Limb Amputation: A Systematic Review of TMS Motor Mapping Studies. Frontiers in neuroscience\| PubMed ID: 32372907	2020
Noninvasive motor cortex stimulation effects on quantitative sensory testing in healthy and chronic pain subjects: a systematic review and meta-analysis. Pain\| PubMed ID: 32453135	2020
Beta-band oscillations as a biomarker of gait recovery in spinal cord injury patients: A quantitative electroencephalography analysis. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology\| PubMed ID: 32540720	2020
Decreased neural inhibitory state in fibromyalgia pain: A cross-sectional study. Neurophysiologie clinique = Clinical neurophysiology\| PubMed ID: 32654884	2020
Evidence-Based Guidelines and Secondary Meta-Analysis for the Use of Transcranial Direct Current Stimulation in Neurological and Psychiatric Disorders. The international journal of neuropsychopharmacology\| PubMed ID: 32710772	2021
Evidence-based decision making during COVID-19 pandemic. Principles and practice of clinical research (2015)\| PubMed ID: 32766450	2020
COVID-19 pandemic and Farr's law: A global comparison and prediction of outbreak acceleration and deceleration rates. PloS one\| PubMed ID: 32941485	2020
Non-invasive neuromodulation effects on painful diabetic peripheral neuropathy: a systematic review and meta-analysis. Scientific reports\| PubMed ID: 33154432	2020
Evidence-based appraisal of blood pressure reduction in spontaneous intracerebral hemorrhage: A scoping review and overview. Clinical neurology and neurosurgery\| PubMed ID: 33517161	2021
Understanding intracortical excitability in phantom limb pain: A multivariate analysis from a multicenter randomized clinical trial. Neurophysiologie clinique = Clinical neurophysiology\| PubMed ID: 33648819	2021
Prevalence and incidence of epilepsy in Latin America and the Caribbean: A systematic review and meta-analysis of population-based studies. Epilepsia\| PubMed ID: 33651439	2021
Specific Electroencephalographic Signatures for Pain and Descending Pain Inhibitory System in Spinal Cord Injury. Pain medicine (Malden, Mass.)\| PubMed ID: 33950263	2022
Prevalence and incidence of diabetic peripheral neuropathy in Latin America and the Caribbean: A systematic review and meta-analysis. PloS one\| PubMed ID: 33984049	2021
Effects of Combined and Alone Transcranial Motor Cortex Stimulation and Mirror Therapy in Phantom Limb Pain: A Randomized Factorial Trial. Neurorehabilitation and neural repair\| PubMed ID: 34060934	2021
Barriers and facilitators for clinical trial participation of underrepresented and non-underrepresented fibromyalgia patients: A cross-sectional internet survey. Heliyon\| PubMed ID: 34286136	2021
Acute disseminated encephalomyelitis and COVID-19: A systematic synthesis of worldwide cases. Journal of neuroimmunology\| PubMed ID: 34371208	2021
Is Surfer's myelopathy an acute hyperextension-induced myelopathy? A systematic synthesis of case studies and proposed diagnostic criteria. Journal of neurology\| PubMed ID: 34477933	2022
Addressing the critical role of gender identity and sex in the planning, analysis, and conduct of clinical trials. Principles and practice of clinical research (2015)\| PubMed ID: 34532571	2021
More work needed on decision analysis for shared decision-making: A scoping review. Journal of clinical epidemiology\| PubMed ID: 34628018	2022
Electroencephalography Signatures for Conditioned Pain Modulation and Pain Perception in Nonspecific Chronic Low Back Pain-An Exploratory Study. Pain medicine (Malden, Mass.)\| PubMed ID: 34633449	2022
No aftereffects of high current density 10 Hz and 20 Hz tACS on sensorimotor alpha and beta oscillations. Scientific reports\| PubMed ID: 34725379	2021
Modulation of the cognitive event-related potential P3 by transcranial direct current stimulation: Systematic review and meta-analysis. Neuroscience and biobehavioral reviews\| PubMed ID: 34742723	2022
Recruitment characteristics and non-adherence associated factors of fibromyalgia patients in a randomized clinical trial: A retrospective survival analysis. Contemporary clinical trials communications\| PubMed ID: 34849424	2021
Increased motor cortex inhibition as a marker of compensation to chronic pain in knee osteoarthritis. Scientific reports\| PubMed ID: 34907209	2021
EEG theta and beta bands as brain oscillations for different knee osteoarthritis phenotypes according to disease severity. Scientific reports\| PubMed ID: 35087082	2022
Global morbidity and mortality of central nervous system tuberculosis: a systematic review and meta-analysis. Journal of neurology\| PubMed ID: 35288778	2022
Home-based transcranial direct current stimulation (tDCS) and motor imagery for phantom limb pain using statistical learning to predict treatment response: an open-label study protocol. Principles and practice of clinical research (2015)\| PubMed ID: 35434309	2021
Accelerating the translation of research findings to clinical practice: insights from phantom limb pain clinical trials. Principles and practice of clinical research (2015)\| PubMed ID: 35434310	2021
Glutamatergic System in Depression and Its Role in Neuromodulatory Techniques Optimization. Frontiers in psychiatry\| PubMed ID: 35492692	2022
Can neural markers be used for fibromyalgia clinical management? Principles and practice of clinical research (2015)\| PubMed ID: 35677778	2022
Greater occipital nerve block for chronic migraine patients: A meta-analysis. Acta neurologica Scandinavica\| PubMed ID: 35726455	2022
Temporal Summation in Fibromyalgia Patients: Comparing Phasic and Tonic Paradigms. Frontiers in pain research (Lausanne, Switzerland)\| PubMed ID: 35812016	2022
Motor cortex inhibition as a fibromyalgia biomarker: a meta-analysis of transcranial magnetic stimulation studies. Brain network and modulation\| PubMed ID: 35845034	2022
Neuroleptic intolerance in the context of anti-N-methyl-D-aspartate receptor encephalitis: A systematic review and synthesis of global case reports. Acta neurologica Scandinavica\| PubMed ID: 36086808	2022
Digitalized transcranial electrical stimulation: A consensus statement. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology\| PubMed ID: 36115809	2022
Editorial: Optimization strategies for pain management with neuromodulation. Frontiers in pain research (Lausanne, Switzerland)\| PubMed ID: 36185771	2022
Association of Mu opioid receptor (A118G) and BDNF (G196A) polymorphisms with rehabilitation-induced cortical inhibition and analgesic response in chronic osteoarthritis pain. International journal of clinical and health psychology : IJCHP\| PubMed ID: 36199368	2023
Burden of Stroke and Population-Attributable Fractions of Risk Factors in Latin America and the Caribbean. Journal of the American Heart Association\| PubMed ID: 36285788	2022
Transcutaneous Auricular Vagus Nerve Stimulation Improves Inflammation but Does Not Interfere with Cardiac Modulation and Clinical Symptoms of Individuals with COVID-19: A Randomized Clinica... Life (Basel, Switzerland)\| PubMed ID: 36295080	2022
Motor event-related synchronization as an inhibitory biomarker of pain severity, sensitivity, and chronicity in patients with knee osteoarthritis. Neurophysiologie clinique = Clinical neurophysiology\| PubMed ID: 36347747	2022
The Analgesic Effect of Transcranial Direct Current Stimulation in Fibromyalgia: A Systematic Review, Meta-Analysis, and Meta-Regression of Potential Influencers of Clinical Effect. Neuromodulation : journal of the International Neuromodulation Society\| PubMed ID: 36435660	2023
Transcutaneous auricular vagus nerve stimulation effects on inflammatory markers and clinical evolution of patients with COVID-19: a pilot randomized clinical trial. Expert review of medical devices\| PubMed ID: 36540947	2022
Insights and Future Directions on the Combined Effects of Mind-Body Therapies with Transcranial Direct Current Stimulation: An Evidence-based Review. The journal of the International Society of Physical and Rehabilitation Medicine\| PubMed ID: 36583065	2022
Detangling the Structural Neural Correlates Associated with Resting versus Dynamic Phantom Limb Pain Intensity Using a Voxel-based Morphometry Analysis. Pain medicine (Malden, Mass.)\| PubMed ID: 36583548	2023
Primary headache disorders in Latin America and the Caribbean: A meta-analysis of population-based studies. Cephalalgia : an international journal of headache\| PubMed ID: 36606574	2023
Development of a Clinical Prediction Rule for Treatment Success with Transcranial Direct Current Stimulation for Knee Osteoarthritis Pain: A Secondary Analysis of a Double-Blind Randomized C... Biomedicines\| PubMed ID: 36672512	2022
Burden of epilepsy in Latin America and The Caribbean: a trend analysis of the Global Burden of Disease Study 1990 - 2019. Lancet regional health. Americas\| PubMed ID: 36778734	2022
Exercise effects on motor function, manual dexterity, and brain oscillatory activity in individuals with Parkinson's disease: Randomized controlled trial protocol. Physiotherapy research international : the journal for researchers and clinicians in physical therapy\| PubMed ID: 37141404	2023
The role of symptoms severity, heart rate, and central sensitization for predicting sleep quality in patients with fibromyalgia. Pain medicine (Malden, Mass.)\| PubMed ID: 37314968	2023
Motor Cortex Inhibition and Facilitation Correlates with Fibromyalgia Compensatory Mechanisms and Pain: A Cross-Sectional Study. Biomedicines\| PubMed ID: 37371638	2023
Editorial: Bench to Bedside - the translation of intracortical inhibition marker to clinical practice. Principles and practice of clinical research (2015)\| PubMed ID: 37449292	2022
Factors associated with pain pressure threshold in both local and remote sites in knee osteoarthritis. PM & R : the journal of injury, function, and rehabilitation\| PubMed ID: 37455395	2024
Non-invasive brain stimulation on clinical symptoms in multiple sclerosis patients: A systematic review and meta-analysis. Multiple sclerosis and related disorders\| PubMed ID: 37595371	2023
Functional and Neural Correlates Associated with Conditioned Pain Modulation in Patients with Chronic Knee Osteoarthritis Pain: A Cross-Sectional Study. Life (Basel, Switzerland)\| PubMed ID: 37629554	2023
Editorial - The Secret Life of Retractions in Scientific Publications. Principles and practice of clinical research (2015)\| PubMed ID: 37693831	2023
Editorial - The Use of Large Language Models in Science: Opportunities and Challenges. Principles and practice of clinical research (2015)\| PubMed ID: 37693832	2023
Editorial - Seeking Brain Homeostatic Compensatory Mechanisms for Pain Control. Principles and practice of clinical research (2015)\| PubMed ID: 37711748	2023
Is brain perfusion correlated to switching mood states and cognitive impairment in bipolar disorder type I? A longitudinal study using perfusion imaging approach. Frontiers in psychiatry\| PubMed ID: 37860170	2023
Association between weight status and migraine in the paediatric population: a systematic review and meta-analysis. Frontiers in neurology\| PubMed ID: 38033769	2023
Preventing posttraumatic stress disorder following childbirth: a systematic review and meta-analysis. American journal of obstetrics and gynecology\| PubMed ID: 38122842	2024
Accelerating the development of noninvasive brain stimulation devices: using design thinking to facilitate its clinical use and acceptance. Expert review of neurotherapeutics\| PubMed ID: 38149610	2024
Noninvasive Neuromodulation Combined With Rehabilitation Therapy Improves Balance and Gait Speed in Patients With Stroke: A Systematic Review and Network Meta-analysis. American journal of physical medicine & rehabilitation\| PubMed ID: 38363653	2024
Distinct patterns of metabolic motor cortex activity for phantom and residual limb pain in people with amputations: A functional near-infrared spectroscopy study. Neurophysiologie clinique = Clinical neurophysiology\| PubMed ID: 38382136	2024
Physical Conditioning, Obesity and Fibromyalgia: Causal Relationship or Confounding? Principles and practice of clinical research (2015)\| PubMed ID: 38433877	2023
Brain-heart interactions in fibromyalgia syndrome. Principles and practice of clinical research (2015)\| PubMed ID: 38434480	2024
Transauricular Vagus Nerve Stimulation (taVNS) enhances Conditioned Pain Modulation (CPM) in healthy subjects: A randomized controlled trial. Brain stimulation\| PubMed ID: 38453004	2024
Non-invasive sound wave brain stimulation with Transcranial Pulse Stimulation (TPS) improves neuropsychiatric symptoms in Alzheimer's disease. Brain stimulation\| PubMed ID: 38513821	2024
Brain compensatory mechanisms in depression and memory complaints in fibromyalgia: the role of theta oscillatory activity. Pain medicine (Malden, Mass.)\| PubMed ID: 38652585	2024
Improved all-cause mortality with left bundle branch area pacing compared to biventricular pacing in cardiac resynchronization therapy: a meta-analysis. Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing\| PubMed ID: 38668934	2024
Chikungunya crisis in the Americas: a comprehensive call for research and innovation. Lancet regional health. Americas\| PubMed ID: 38737774	2024
Peri-ictal psychiatric manifestations in people with epilepsy: An umbrella review. Epilepsia open\| PubMed ID: 38816942	2024
Exercise effects on cortical excitability in pain populations: A systematic review and meta-analysis. Physiotherapy research international : the journal for researchers and clinicians in physical therapy\| PubMed ID: 38861661	2024
Enhancing Dissemination and Understanding in Clinical Research Protocols: Optimizing Visual Communication in a Phantom Limb Pain Clinical Trial. Principles and practice of clinical research (2015)\| PubMed ID: 38894749	2024
Developing transcranial direct current stimulation as a treatment for phantom limb pain: from pilot mechanistic studies to large clinical studies. Principles and practice of clinical research (2015)\| PubMed ID: 38894750	2024
Evidence of bottom-up homeostatic modulation induced taVNS during emotional and Go/No-Go tasks. Experimental brain research\| PubMed ID: 38963558	2024
Neuropsychiatric drugs and a neurophysiological marker as predictors of health-related quality of life in patients with phantom limb pain. Pain medicine (Malden, Mass.)\| PubMed ID: 38964349	2024
A neural signature for brain compensation in stroke with EEG and TMS: Insights from the DEFINE cohort study. Neurophysiologie clinique = Clinical neurophysiology\| PubMed ID: 38970865	2024
The impact of education level and socioeconomic status on the association between depressive symptoms and memory in an older population in Latin America: An exploratory analysis from the Bra... Dialogues in health\| PubMed ID: 38975569	2024
The Impact of Obesity as a Peripheral Disruptor of Brain Inhibitory Mechanisms in Fibromyalgia: A Cross-Sectional Study. Journal of clinical medicine\| PubMed ID: 38999444	2024
Cross-sectional and longitudinal analysis of conditioned pain modulation and pain in fibromyalgia: CPM as an effect modifier of pain changes over time. Physiotherapy research international : the journal for researchers and clinicians in physical therapy\| PubMed ID: 39055778	2024
Adaptive and Compensatory Neural Signatures in Fibromyalgia: An Analysis of Resting-State and Stimulus-Evoked EEG Oscillations. Biomedicines\| PubMed ID: 39062001	2024
Age as an Effect Modifier of the Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Heart Rate Variability in Healthy Subjects. Journal of clinical medicine\| PubMed ID: 39064307	2024
Resting-state electroencephalography delta and theta bands as compensatory oscillations in chronic neuropathic pain: a secondary data analysis. Brain network and modulation\| PubMed ID: 39119588	2024
Transcutaneous vagus nerve stimulation effects on chronic pain: systematic review and meta-analysis. Pain reports\| PubMed ID: 39131814	2024
Psychological Factors Modulate Quantitative Sensory Testing Measures in Fibromyalgia Patients: A Systematic Review and Meta-Regression Analysis. Psychosomatic medicine\| PubMed ID: 39225326	2024
Clinical Characteristics Associated with the PLP-PLS Index, a New Potential Metric to Phenotype Phantom Limb Pain. Biomedicines\| PubMed ID: 39335548	2024
The Link between Endogenous Pain Modulation Changes and Clinical Improvement in Fibromyalgia Syndrome: A Meta-Regression Analysis. Biomedicines\| PubMed ID: 39335610	2024
Neural correlates of phantom motor execution: A functional neuroimaging systematic review and meta-analysis. Cortex; a journal devoted to the study of the nervous system and behavior\| PubMed ID: 39341715	2024
Effect of Neurostimulation on Chronic Pancreatic Pain: A Systematic Review. Neuromodulation : journal of the International Neuromodulation Society\| PubMed ID: 39365205	2024
Disruptive compensatory mechanisms in fibromyalgia syndrome and their association with pharmacological agents. Experimental brain research\| PubMed ID: 39368024	2024
High Body Mass Index Disrupts the Homeostatic Effects of Pain Inhibitory Control in the Symptomatology of Patients With Fibromyalgia. The journal of pain\| PubMed ID: 39374799	2024
The Endogenous Pain Modulatory System as a Healing Mechanism: A Proposal on How to Measure and Modulate It. NeuroSci\| PubMed ID: 39483278	2024
Looking for the future: Gaps in research and clinical rehabilitation for chronic chikungunya arthralgia. Brazilian journal of physical therapy\| PubMed ID: 39549343	2024
Adaptive Compensatory Neurophysiological Biomarkers of Motor Recovery Post-Stroke: Electroencephalography and Transcranial Magnetic Stimulation Insights from the DEFINE Cohort Study. Brain sciences\| PubMed ID: 39766456	2024
Haptic Technology: Exploring Its Underexplored Clinical Applications-A Systematic Review. Biomedicines\| PubMed ID: 39767709	2024
Differences in Plasma BDNF Levels Between Chronic Primary Musculoskeletal Pain, Fibromyalgia Syndrome, and Asymptomatic Subjects: A Cross-Sectional Study. Biological research for nursing\| PubMed ID: 39789935	2025
Associations of Voice Metrics with Postural Function in Parkinson's Disease. Life (Basel, Switzerland)\| PubMed ID: 39859967	2024
The Role of Maladaptive Plasticity in Modulating Pain Pressure Threshold Post-Spinal Cord Injury. Healthcare (Basel, Switzerland)\| PubMed ID: 39942436	2025
The Association of Pain Medication Usage and Quantitative Sensory Testing Outcomes in Fibromyalgia Patients: A Secondary Data Analysis. NeuroSci\| PubMed ID: 39982267	2025
Association of Chronic Pain with Motor Symptom Severity in Parkinson's Disease: An Exploratory Cross-Sectional Analysis. Life (Basel, Switzerland)\| PubMed ID: 40003677	2025
Pain modulation in amputees: Exploring conditioned pain modulation and its influencing factors on amputated and non-amputated sides: A cross-sectional study. British journal of pain\| PubMed ID: 40276723	2025
Neurocircuitry basis of motor cortex-related analgesia as an emerging approach for chronic pain management. Nature. Mental health\| PubMed ID: 40376387	2024
The role of biological sex in neurophysiological associations of patients with chronic osteoarthritis pain: a prospective cross-sectional study. Brazilian journal of anesthesiology (Elsevier)\| PubMed ID: 40383367	2025
Obesity and Systemic Inflammation Disrupt the Compensatory Role of Physical Activity in Chronic Pain Conditions. Biomedicines\| PubMed ID: 40426937	2025
TMS-Indexed neurophysiological signatures of neural compensation in spinal cord injury: associations with injury level, motor function, and affective modulation. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology\| PubMed ID: 40471507	2025