Department of Physiology and Pharmacology,
Cumming School of Medicine,
Department of Biochemistry and Molecular Biology,
Department of Physiology and Pharmacology, Cumming School of Medicine,
Department of Biochemistry and Molecular Biology, Cumming School of Medicine
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Proteoglycan 4: From Mere Lubricant to Regulator of Tissue Homeostasis and Inflammation: Does proteoglycan 4 have the ability to buffer the inflammatory response?
BioEssays : news and reviews in molecular, cellular and developmental biology Jan, 2019 | Pubmed ID: 30485469
Matrix metalloproteinases in the CNS: interferons get nervous.
Cellular and molecular life sciences : CMLS Aug, 2019 | Pubmed ID: 31165203
Active thrombin produced by the intestinal epithelium controls mucosal biofilms.
Nature communications Jul, 2019 | Pubmed ID: 31324782
N-Terminomics/TAILS Profiling of Proteases and Their Substrates in Ulcerative Colitis.
ACS chemical biology Nov, 2019 | Pubmed ID: 31393699
Matrix Metalloproteases as Influencers of the Cells' Social Media.
International journal of molecular sciences Aug, 2019 | Pubmed ID: 31394726
N-Terminomics/TAILS Profiling of Macrophages after Chemical Inhibition of Legumain.
Biochemistry Jan, 2020 | Pubmed ID: 31774660
Intracellular Localization in Zebrafish Muscle and Conserved Sequence Features Suggest Roles for Gelatinase A Moonlighting in Sarcomere Maintenance.
Biomedicines Nov, 2019 | Pubmed ID: 31795436
Proteomics and Imaging in Crohn's Disease: TAILS of Unlikely Allies.
Trends in pharmacological sciences Feb, 2020 | Pubmed ID: 31952817
The Pharmacological TAILS of Matrix Metalloproteinases and Their Inhibitors.
Pharmaceuticals (Basel, Switzerland) Dec, 2020 | Pubmed ID: 33396445
TRPV1 Activation Promotes β-arrestin2 Interaction with the Ribosomal Biogenesis Machinery in the Nucleolus:Implications for p53 Regulation and Neurite Outgrowth.
International journal of molecular sciences Feb, 2021 | Pubmed ID: 33668926
Harnessing the Benefits of Neuroinflammation: Generation of Macrophages/Microglia with Prominent Remyelinating Properties.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2021 | Pubmed ID: 33712513
Exercise rapidly alters proteomes in mice following spinal cord demyelination.
Scientific reports Mar, 2021 | Pubmed ID: 33790323
The Nerves to Conduct a Multiple Sclerosis Crime Investigation.
International journal of molecular sciences Mar, 2021 | Pubmed ID: 33801441
Entamoeba histolytica exploits the autophagy pathway in macrophages to trigger inflammation in disease pathogenesis.
Mucosal immunology Sep, 2021 | Pubmed ID: 33963264
Proteoglycan 4 (PRG4) expression and function in dry eye associated inflammation.
Experimental eye research Jul, 2021 | Pubmed ID: 34048779
PGC-1α mediates a metabolic host defense response in human airway epithelium during rhinovirus infections.
Nature communications Jun, 2021 | Pubmed ID: 34135327
PNKP is required for maintaining the integrity of progenitor cell populations in adult mice.
Life science alliance Sep, 2021 | Pubmed ID: 34226276
Nasal Septum Deviation as the Consequence of BMP-Controlled Changes to Cartilage Properties.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34249945
Association of Circulating Fibrocytes With Fibrostenotic Small Bowel Crohn's Disease.
Inflammatory bowel diseases Feb, 2022 | Pubmed ID: 34428284
Biochemical Tools for Tracking Proteolysis.
Journal of proteome research Dec, 2021 | Pubmed ID: 34491759
Entamoeba histolytica activation of caspase-1 degrades cullin that attenuates NF-κB dependent signaling from macrophages.
PLoS pathogens Sep, 2021 | Pubmed ID: 34499701
Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19.
Nature medicine Jan, 2022 | Pubmed ID: 34782790
Proteomics Analysis of Tears and Saliva From Sjogren's Syndrome Patients.
Frontiers in pharmacology , 2021 | Pubmed ID: 34950038
Inferring early-life host and microbiome functions by mass spectrometry-based metaproteomics and metabolomics.
Computational and structural biotechnology journal , 2022 | Pubmed ID: 35024099
Metaproteomic profiling of fungal gut colonization in gnotobiotic mice.
Animal microbiome Feb, 2022 | Pubmed ID: 35193703
Proteomic Analysis Suggests Altered Mitochondrial Metabolic Profile Associated With Diabetic Cardiomyopathy.
Frontiers in cardiovascular medicine , 2022 | Pubmed ID: 35310970
Identification of Common and Distinct Pathways in Inflammatory Bowel Disease and Colorectal Cancer: A Hypothesis Based on Weighted Gene Co-Expression Network Analysis.
Frontiers in genetics , 2022 | Pubmed ID: 35432477
Proteomics and Metabolomics Profiling of Platelets and Plasma Mediators of Thrombo-Inflammation in Gestational Hypertension and Preeclampsia.
Cells Apr, 2022 | Pubmed ID: 35455936
N-Terminomics/TAILS of Tissue and Liquid Biopsies.
Methods in molecular biology (Clifton, N.J.) , 2022 | Pubmed ID: 35612737
Proteoglycan 4 is present within the dura mater and produced by mesenchymal progenitor cells.
Cell and tissue research Sep, 2022 | Pubmed ID: 35704103
Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization.
Immunity Jul, 2022 | Pubmed ID: 35709757
Matrix Metalloproteinases: From Molecular Mechanisms to Physiology, Pathophysiology, and Pharmacology.
Pharmacological reviews Jul, 2022 | Pubmed ID: 35738680
Lymph-derived chemokines direct early neutrophil infiltration in the lymph nodes upon skin infection.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2022 | Pubmed ID: 35914162
The expression pattern of Immune checkpoints after chemo/radiotherapy in the tumor microenvironment.
Frontiers in immunology , 2022 | Pubmed ID: 35967381
Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium.
Journal of innate immunity Sep, 2022 | Pubmed ID: 36116427
Hox-driven conditional immortalization of myeloid and lymphoid progenitors: Uses, advantages, and future potential.
Traffic (Copenhagen, Denmark) Nov, 2022 | Pubmed ID: 36117140
Limits of Cardiovascular Adaptation During an Extreme Ultramarathon: Insights From Serial Multidimensional, Multiparametric CMR.
JACC. Case reports Sep, 2022 | Pubmed ID: 36124158
NR4A1 modulates intestinal smooth muscle cell phenotype and dampens inflammation-associated intestinal remodeling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Nov, 2022 | Pubmed ID: 36250380
Fibroblast inflammatory priming determines regenerative versus fibrotic skin repair in reindeer.
Cell Dec, 2022 | Pubmed ID: 36493752
Hypercoagulability and Inflammatory Markers in a Case of Congenital Thrombotic Thrombocytopenic Purpura Complicated by Fetal Demise.
Journal of clinical medicine Nov, 2022 | Pubmed ID: 36498688
Heightened Procoagulation after Post-Operative Thromboprophylaxis Completion in Patients with Metastatic Bone Disease from Primary Colorectal Cancer.
Journal of clinical medicine Dec, 2022 | Pubmed ID: 36556013
The roles of proteases in prostate cancer.
IUBMB life Jun, 2023 | Pubmed ID: 36598826
Romiplostim drug presence in pregnancy and lactation.
Blood May, 2023 | Pubmed ID: 36848631
Overexpression of facilitative glucose transporter-3 and membrane procoagulation in maternal platelets of preeclamptic pregnancy.
Journal of thrombosis and haemostasis : JTH Jul, 2023 | Pubmed ID: 36963633
Tryptase β regulation of joint lubrication and inflammation via proteoglycan-4 in osteoarthritis.
Nature communications Apr, 2023 | Pubmed ID: 37024468
N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection.
Molecular & cellular proteomics : MCP May, 2023 | Pubmed ID: 37030595
Host innate immune responses and microbiome profile of neonatal calves challenged with and the effect of bovine colostrum supplementation.
Frontiers in cellular and infection microbiology , 2023 | Pubmed ID: 37207189
Mesenchymal progenitor cells from non-inflamed versus inflamed synovium post-ACL injury present with distinct phenotypes and cartilage regeneration capacity.
Stem cell research & therapy Jun, 2023 | Pubmed ID: 37357305
IgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing.
Frontiers in immunology , 2023 | Pubmed ID: 37359538
Perinatal iron restriction is associated with changes in neonatal cardiac function and structure in a sex-dependent manner.
Clinical science (London, England : 1979) Aug, 2023 | Pubmed ID: 37463130
Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy.
Cell genomics Aug, 2023 | Pubmed ID: 37601967
Julian Wolf1,2,
Teja Chemudupati1,2,
Aarushi Kumar1,2,
Ditte K. Rasmussen1,2,
Karen M. Wai2,
Robert T. Chang2,
Artis A. Montague2,
Peter H. Tang3,4,
Alexander G. Bassuk5,6,7,
Antoine Dufour8,9,
Prithvi Mruthrunjaya2,
Vinit B. Mahajan1,2,10
1Molecular Surgery Laboratory, Stanford University,
2Department of Ophthalmology, Byers Eye Institute, Stanford University,
3Department of Ophthalmology and Visual Neurosciences, University of Minnesota,
4, Retina Consultants of Minnesota,
5Department of Pediatrics, University of Iowa,
6Department of Neurology, University of Iowa,
7The Iowa Neuroscience Institute (INI), University of Iowa,
8Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary,
9Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary,
10, Veterans Affairs Palo Alto Health Care System
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