Robin J. M. Franklin

Wellcome Trust-MRC Cambridge Stem Cell Institute, University of Cambridge

Affiliated withUniversity of Cambridge Cambridge Institute of Science

Research Area

Neuroscience

Biography

Robin J. M. Franklin has not added Biography.
If you are Robin J. M. Franklin and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

Article Total : 1	Year
Publication title	2024

Other Publications

Article	Year
Transplanting oligodendrocyte progenitors into the adult CNS. Journal of anatomy\| PubMed ID: 9034879	1997
What roles do growth factors play in CNS remyelination? Progress in brain research\| PubMed ID: 11544987	2001
Recognition and diagnosis of lysosomal storage diseases in the cat and dog. Journal of veterinary internal medicine\| PubMed ID: 11899921	2002
The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11923409	2002
Ageing and CNS remyelination. Neuroreport\| PubMed ID: 12004191	2002
Remyelination of the demyelinated CNS: the case for and against transplantation of central, peripheral and olfactory glia. Brain research bulletin\| PubMed ID: 12031280	2002
Why does remyelination fail in multiple sclerosis? Nature reviews. Neuroscience\| PubMed ID: 12209119	2002
Expression of the POU-domain transcription factors SCIP/Oct-6 and Brn-2 is associated with Schwann cell but not oligodendrocyte remyelination of the CNS. Molecular and cellular neurosciences\| PubMed ID: 12213447	2002
Transplant mediated repair of the central nervous system: an imminent solution? Current opinion in neurology\| PubMed ID: 12447108	2002
Meningeal cells enhance limited CNS remyelination by transplanted olfactory ensheathing cells. Brain : a journal of neurology\| PubMed ID: 12566281	2003
Lentiviral vectors for gene delivery to normal and demyelinated white matter. Glia\| PubMed ID: 12594737	2003
Remyelination by transplanted olfactory ensheathing cells. Anatomical record. Part B, New anatomist\| PubMed ID: 12619088	2003
Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system. Brain : a journal of neurology\| PubMed ID: 12764059	2003
Quantifying the early stages of remyelination following cuprizone-induced demyelination. Brain pathology (Zurich, Switzerland)\| PubMed ID: 12946022	2003
Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS. The European journal of neuroscience\| PubMed ID: 14622186	2003
Olfactory ensheathing cells induce less host astrocyte response and chondroitin sulphate proteoglycan expression than Schwann cells following transplantation into adult CNS white matter. Experimental neurology\| PubMed ID: 14637095	2003
CNS axons retain their competence for myelination throughout life. Glia\| PubMed ID: 14730704	2004
Neuroscience. The mysteries of myelin unwrapped. Science (New York, N.Y.)\| PubMed ID: 15118149	2004
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain : a journal of neurology\| PubMed ID: 15289265	2004
Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS. Molecular and cellular neurosciences\| PubMed ID: 15519240	2004
Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation ... The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15525765	2004
Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination. Journal of neuroimmunology\| PubMed ID: 15589038	2005
Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiology of disease\| PubMed ID: 15649707	2005
Mechanisms of CNS remyelination--the key to therapeutic advances. Journal of the neurological sciences\| PubMed ID: 15949498	2005
Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination. Neurobiology of aging\| PubMed ID: 16051398	2006
Stem cells, progenitors and myelin repair. Journal of anatomy\| PubMed ID: 16185249	2005
Autologous olfactory glial cell transplantation is reliable and safe in naturally occurring canine spinal cord injury. Journal of neurotrauma\| PubMed ID: 16305316	2005
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 16399703	2006
Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS. Experimental neurology\| PubMed ID: 16410004	2006
Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system. Journal of neuroscience research\| PubMed ID: 16429447	2006
Magnetic resonance imaging of functional Schwann cell transplants labelled with magnetic microspheres. NeuroImage\| PubMed ID: 16442816	2006
Comparison of cell populations derived from canine olfactory bulb and olfactory mucosal cultures. American journal of veterinary research\| PubMed ID: 16740101	2006
Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS. Experimental neurology\| PubMed ID: 16797535	2006
Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells. Glia\| PubMed ID: 16856149	2006
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17021167	2006
Calponin is expressed by fibroblasts and meningeal cells but not olfactory ensheathing cells in the adult peripheral olfactory system. Glia\| PubMed ID: 17078028	2007
Mutations in genes causing human familial isolated hyperparathyroidism do not account for hyperparathyroidism in Keeshond dogs. Veterinary journal (London, England : 1997)\| PubMed ID: 17158076	2007
Myelin repair: the role of stem and precursor cells in multiple sclerosis. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 17282989	2008
Myelin regeneration in demyelinating disorders: new developments in biology and clinical pathology. Current opinion in neurology\| PubMed ID: 17495623	2007
Promoting remyelination in multiple sclerosis by endogenous adult neural stem/precursor cells: defining cellular targets. Journal of the neurological sciences\| PubMed ID: 17570402	2008
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. The Journal of cell biology\| PubMed ID: 17576798	2007
Development of a universal measure of quadrupedal forelimb-hindlimb coordination using digital motion capture and computerised analysis. BMC neuroscience\| PubMed ID: 17877823	2007
Contrasting effects of basic fibroblast growth factor and epidermal growth factor on mouse neonatal olfactory mucosa cells. The European journal of neuroscience\| PubMed ID: 18088275	2007
The biology of CNS remyelination: the key to therapeutic advances. Journal of neurology\| PubMed ID: 18317673	2008
Serum-free medium provides a clinically relevant method to increase olfactory ensheathing cell numbers in olfactory mucosa cell culture. Cell transplantation\| PubMed ID: 18351018	2008
Taking ageing into account in remyelination-based therapies for multiple sclerosis. Journal of the neurological sciences\| PubMed ID: 18539300	2008
Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination. Neurobiology of disease\| PubMed ID: 18539470	2008
An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss. Journal of neuroimmunology\| PubMed ID: 18672298	2008
Remyelination in the CNS: from biology to therapy. Nature reviews. Neuroscience\| PubMed ID: 18931697	2008
Quantification of deficits in lateral paw positioning after spinal cord injury in dogs. BMC veterinary research\| PubMed ID: 19032742	2008
Zebrafish myelination: a transparent model for remyelination? Disease models & mechanisms\| PubMed ID: 19093028	2008
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency. Nature neuroscience\| PubMed ID: 19160500	2008
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling. Brain : a journal of neurology\| PubMed ID: 19208690	2009
Transplanted oligodendrocyte precursor cells reduce neurodegeneration in a model of glaucoma. Investigative ophthalmology & visual science\| PubMed ID: 19357352	2009
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS. Genes & development\| PubMed ID: 19515974	2009
Remyelination - An effective means of neuroprotection. Hormones and behavior\| PubMed ID: 19538961	2010
Up-regulation of oligodendrocyte precursor cell alphaV integrin and its extracellular ligands during central nervous system remyelination. Journal of neuroscience research\| PubMed ID: 19739252	2009
Temporal dynamics of myelination in the zebrafish spinal cord. Glia\| PubMed ID: 20140960	2010
FGF but not EGF induces phosphorylation of the cAMP response element binding protein in olfactory mucosa-derived cell cultures. Experimental cell research\| PubMed ID: 20211167	2010
Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects. Neuropharmacology\| PubMed ID: 20450924	2010
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell stem cell\| PubMed ID: 20569695	2010
Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy. Journal of biomechanics\| PubMed ID: 20656292	2010
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination. Annals of neurology\| PubMed ID: 20853437	2010
Retinoid X receptor gamma signaling accelerates CNS remyelination. Nature neuroscience\| PubMed ID: 21131950	2011
Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21248132	2011
Regenerative medicine in multiple sclerosis: identifying pharmacological targets of adult neural stem cell differentiation. Neurochemistry international\| PubMed ID: 21300122	2011
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis. Brain : a journal of neurology\| PubMed ID: 21705418	2011
Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nature neuroscience\| PubMed ID: 21706018	2011
Myelin regeneration in multiple sclerosis: targeting endogenous stem cells. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 21904791	2011
Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22160722	2012
Rejuvenation of regeneration in the aging central nervous system. Cell stem cell\| PubMed ID: 22226359	2012
Mechanical environment modulates biological properties of oligodendrocyte progenitor cells. Stem cells and development\| PubMed ID: 22646081	2012
Accelerated axonal loss following acute CNS demyelination in mice lacking protein tyrosine phosphatase receptor type Z. The American journal of pathology\| PubMed ID: 22940073	2012
Neuroprotection and repair in multiple sclerosis. Nature reviews. Neurology\| PubMed ID: 23026979	2012
Embryonic-derived olfactory ensheathing cells remyelinate focal areas of spinal cord demyelination more efficiently than neonatal or adult-derived cells. Cell transplantation\| PubMed ID: 23031825	2013
Autologous olfactory mucosal cell transplants in clinical spinal cord injury: a randomized double-blinded trial in a canine translational model. Brain : a journal of neurology\| PubMed ID: 23169917	2012
Current status of myelin replacement therapies in multiple sclerosis. Progress in brain research\| PubMed ID: 23186717	2012
Do your glial cells make you clever? Cell stem cell\| PubMed ID: 23472865	2013
Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination. Brain : a journal of neurology\| PubMed ID: 23518706	2013
Myokymia and neuromyotonia in veterinary medicine: a comparison with peripheral nerve hyperexcitability syndrome in humans. Veterinary journal (London, England : 1997)\| PubMed ID: 23583699	2013
Neural precursor cells cultured at physiologically relevant oxygen tensions have a survival advantage following transplantation. Stem cells translational medicine\| PubMed ID: 23677643	2013
Ageing stem and progenitor cells: implications for rejuvenation of the central nervous system. Development (Cambridge, England)\| PubMed ID: 23715549	2013
Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis. The European journal of neuroscience\| PubMed ID: 23763823	2013
The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche. Experimental neurology\| PubMed ID: 23830949	2013
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nature neuroscience\| PubMed ID: 23872599	2013
Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination. EMBO molecular medicine\| PubMed ID: 24293318	2013
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes. PLoS biology\| PubMed ID: 24391468	2013
Cell therapy for spinal cord injuries: what is really going on? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry\| PubMed ID: 24415275	2014
The translational biology of remyelination: past, present, and future. Glia\| PubMed ID: 24446279	2014
Auxetic nuclei in embryonic stem cells exiting pluripotency. Nature materials\| PubMed ID: 24747782	2014
Multiple sclerosis genetics. The Lancet. Neurology\| PubMed ID: 24852507	2014
Special issue on stem cells: "the end of the beginning". Experimental neurology\| PubMed ID: 24950181	2014
Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. Nature medicine\| PubMed ID: 24997607	2014
Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression. Nature communications\| PubMed ID: 25014177	2014
The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination. Glia\| PubMed ID: 25156142	2015
Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25568099	2015
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells. Experimental neurology\| PubMed ID: 25819103	2015
The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25904802	2015
Fibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions. Glia\| PubMed ID: 25913734	2015
Glia Disease and Repair-Remyelination. Cold Spring Harbor perspectives in biology\| PubMed ID: 25986556	2015
Regenerative Medicines for Remyelination: From Aspiration to Reality. Cell stem cell\| PubMed ID: 26046755	2015
Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell Remyelination. The American journal of pathology\| PubMed ID: 26193667	2015
Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26290228	2015
Discovery of a novel neuroprotectant, BHDPC, that protects against MPP+/MPTP-induced neuronal death in multiple experimental models. Free radical biology & medicine\| PubMed ID: 26415025	2015
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors. Nature communications\| PubMed ID: 26439639	2015
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination. Brain : a journal of neurology\| PubMed ID: 26463675	2015
Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation. Glia\| PubMed ID: 26576485	2016
Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation. The Journal of cell biology\| PubMed ID: 26644513	2015
Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta neuropathologica\| PubMed ID: 26687980	2016
Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes. Annals of clinical and translational neurology\| PubMed ID: 26734659	2015
Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination. The American journal of pathology\| PubMed ID: 26773350	2016
Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage. Cell reports\| PubMed ID: 27149841	2016
Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline. Cell reports\| PubMed ID: 27149850	2016
Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta neuropathologica\| PubMed ID: 27161252	2016
CNS Remyelination and the Innate Immune System. Frontiers in cell and developmental biology\| PubMed ID: 27200350	2016
Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy. Acta neuropathologica communications\| PubMed ID: 27552807	2016
Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) via β1 Integrin. International journal of molecular sciences\| PubMed ID: 27879672	2016
MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter. Nature biotechnology\| PubMed ID: 27918546	2016
Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 27930320	2016
Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice. Stem cell reports\| PubMed ID: 28196689	2017
Regulatory T cells promote myelin regeneration in the central nervous system. Nature neuroscience\| PubMed ID: 28288125	2017
Efficient Remyelination Requires DNA Methylation. eNeuro\| PubMed ID: 28451635	2017
Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination. Acta neuropathologica\| PubMed ID: 28484846	2017
Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease. Progress in brain research\| PubMed ID: 28554395	2017
Do Not Adjust Your Mind: The Fault Is in Your Glia. Cell stem cell\| PubMed ID: 28777939	2017
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination. Cell reports\| PubMed ID: 28834740	2017
Serum-Free Medium Provides a Clinically Relevant Method to Increase Olfactory Ensheathing Cell Numbers in Olfactory Mucosa Cell Culture. Cell transplantation\| PubMed ID: 28866922	2007
Regenerating CNS myelin - from mechanisms to experimental medicines. Nature reviews. Neuroscience\| PubMed ID: 29142295	2017
Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury. Brain : a journal of neurology\| PubMed ID: 29244098	2018
A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 30228229	2018
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes. Immunity\| PubMed ID: 30471926	2019
Toxin-Based Models to Investigate Demyelination and Remyelination. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 30820910	2019
Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors. Glia\| PubMed ID: 30861188	2019
SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke. EBioMedicine\| PubMed ID: 30905846	2019
Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity? Glia\| PubMed ID: 30968471	2019
Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells. Frontiers in cellular neuroscience\| PubMed ID: 30971893	2019
Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination. Glia\| PubMed ID: 31038798	2019
Neuronal vulnerability and multilineage diversity in multiple sclerosis. Nature\| PubMed ID: 31316211	2019
Niche stiffness underlies the ageing of central nervous system progenitor cells. Nature\| PubMed ID: 31413369	2019
Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells. Nature\| PubMed ID: 31462780	2019
Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells. Cell stem cell\| PubMed ID: 31585093	2019
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation. Cell stem cell\| PubMed ID: 31585094	2019
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31740610	2019
Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron\| PubMed ID: 31924446	2020
The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelination. Glia\| PubMed ID: 32017258	2020
Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta neuropathologica\| PubMed ID: 32030468	2020
Correction to: Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. Acta neuropathologica\| PubMed ID: 32211925	2020
Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis. Cell stem cell\| PubMed ID: 32386552	2020
Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing. Molecular & cellular proteomics : MCP\| PubMed ID: 32434922	2020
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis. Acta neuropathologica\| PubMed ID: 32572598	2020
The Role of Astrocytes in Remyelination. Trends in neurosciences\| PubMed ID: 32620289	2020
Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin. Seminars in cell & developmental biology\| PubMed ID: 33082115	2021
Schwann cell remyelination of the central nervous system: why does it happen and what are the benefits? Open biology\| PubMed ID: 33497588	2021
Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes. Nature genetics\| PubMed ID: 33589840	2021
Author Correction: Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes. Nature genetics\| PubMed ID: 33637963	2021
Neuroprotective effects of Sonic hedgehog agonist SAG in a rat model of neonatal stroke. Pediatric research\| PubMed ID: 33654279	2021
A map of transcriptional heterogeneity and regulatory variation in human microglia. Nature genetics\| PubMed ID: 34083789	2021
Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence. Cell reports\| PubMed ID: 34260928	2021
Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity? Frontiers in cellular neuroscience\| PubMed ID: 34381334	2021
Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study. The Lancet. Neurology\| PubMed ID: 34418398	2021
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain. Nature neuroscience\| PubMed ID: 35260865	2022
Remyelination in humans due to a retinoid-X receptor agonist is age-dependent. Annals of clinical and translational neurology\| PubMed ID: 35587315	2022
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis. Neuropathology and applied neurobiology\| PubMed ID: 36181265	2023
Ageing and multiple sclerosis. The Lancet. Neurology\| PubMed ID: 36216015	2023
CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities. Neuron\| PubMed ID: 36228613	2022
Cell-free DNA-based liquid biopsies in neurology. Brain : a journal of neurology\| PubMed ID: 36408894	2023
SARM1 detection in myelinating glia: / is dispensable for PNS and CNS myelination in zebrafish and mice. Frontiers in cellular neuroscience\| PubMed ID: 37091921	2023
Myc determines the functional age state of oligodendrocyte progenitor cells. Nature aging\| PubMed ID: 37117631	2021
Targeted evolution of adeno-associated virus capsids for systemic transgene delivery to microglia and tissue-resident macrophages. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 37603759	2023
Remyelination in the Central Nervous System. Cold Spring Harbor perspectives in biology\| PubMed ID: 38316552	2024