Wellcome Trust-MRC Cambridge Stem Cell Institute
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Transplanting oligodendrocyte progenitors into the adult CNS.
Journal of anatomy Jan, 1997 | Pubmed ID: 9034879
What roles do growth factors play in CNS remyelination?
Progress in brain research , 2001 | Pubmed ID: 11544987
Recognition and diagnosis of lysosomal storage diseases in the cat and dog.
Journal of veterinary internal medicine , 2002 | Pubmed ID: 11899921
The age-related decrease in CNS remyelination efficiency is attributable to an impairment of both oligodendrocyte progenitor recruitment and differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2002 | Pubmed ID: 11923409
Ageing and CNS remyelination.
Neuroreport May, 2002 | Pubmed ID: 12004191
Remyelination of the demyelinated CNS: the case for and against transplantation of central, peripheral and olfactory glia.
Brain research bulletin Apr, 2002 | Pubmed ID: 12031280
Why does remyelination fail in multiple sclerosis?
Nature reviews. Neuroscience Sep, 2002 | Pubmed ID: 12209119
Expression of the POU-domain transcription factors SCIP/Oct-6 and Brn-2 is associated with Schwann cell but not oligodendrocyte remyelination of the CNS.
Molecular and cellular neurosciences Aug, 2002 | Pubmed ID: 12213447
Transplant mediated repair of the central nervous system: an imminent solution?
Current opinion in neurology Dec, 2002 | Pubmed ID: 12447108
Meningeal cells enhance limited CNS remyelination by transplanted olfactory ensheathing cells.
Brain : a journal of neurology Mar, 2003 | Pubmed ID: 12566281
Lentiviral vectors for gene delivery to normal and demyelinated white matter.
Glia Apr, 2003 | Pubmed ID: 12594737
Remyelination by transplanted olfactory ensheathing cells.
Anatomical record. Part B, New anatomist Mar, 2003 | Pubmed ID: 12619088
Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system.
Brain : a journal of neurology Jun, 2003 | Pubmed ID: 12764059
Quantifying the early stages of remyelination following cuprizone-induced demyelination.
Brain pathology (Zurich, Switzerland) Jul, 2003 | Pubmed ID: 12946022
Increasing local levels of neuregulin (glial growth factor-2) by direct infusion into areas of demyelination does not alter remyelination in the rat CNS.
The European journal of neuroscience Oct, 2003 | Pubmed ID: 14622186
Olfactory ensheathing cells induce less host astrocyte response and chondroitin sulphate proteoglycan expression than Schwann cells following transplantation into adult CNS white matter.
Experimental neurology Nov, 2003 | Pubmed ID: 14637095
CNS axons retain their competence for myelination throughout life.
Glia Feb, 2004 | Pubmed ID: 14730704
Neuroscience. The mysteries of myelin unwrapped.
Science (New York, N.Y.) Apr, 2004 | Pubmed ID: 15118149
Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.
Brain : a journal of neurology Sep, 2004 | Pubmed ID: 15289265
Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS.
Molecular and cellular neurosciences Nov, 2004 | Pubmed ID: 15519240
Superparamagnetic iron oxide-labeled Schwann cells and olfactory ensheathing cells can be traced in vivo by magnetic resonance imaging and retain functional properties after transplantation into the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2004 | Pubmed ID: 15525765
Minocycline-mediated inhibition of microglia activation impairs oligodendrocyte progenitor cell responses and remyelination in a non-immune model of demyelination.
Journal of neuroimmunology Jan, 2005 | Pubmed ID: 15589038
Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression.
Neurobiology of disease Feb, 2005 | Pubmed ID: 15649707
Mechanisms of CNS remyelination--the key to therapeutic advances.
Journal of the neurological sciences Jun, 2005 | Pubmed ID: 15949498
Differences in the early inflammatory responses to toxin-induced demyelination are associated with the age-related decline in CNS remyelination.
Neurobiology of aging Sep, 2006 | Pubmed ID: 16051398
Stem cells, progenitors and myelin repair.
Journal of anatomy Sep, 2005 | Pubmed ID: 16185249
Autologous olfactory glial cell transplantation is reliable and safe in naturally occurring canine spinal cord injury.
Journal of neurotrauma Nov, 2005 | Pubmed ID: 16305316
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2006 | Pubmed ID: 16399703
Oligodendrocyte progenitor cell (OPC) transplantation is unlikely to offer a means of preventing X-irradiation induced damage in the CNS.
Experimental neurology Mar, 2006 | Pubmed ID: 16410004
Corticosteroids delay remyelination of experimental demyelination in the rodent central nervous system.
Journal of neuroscience research Mar, 2006 | Pubmed ID: 16429447
Magnetic resonance imaging of functional Schwann cell transplants labelled with magnetic microspheres.
NeuroImage May, 2006 | Pubmed ID: 16442816
Comparison of cell populations derived from canine olfactory bulb and olfactory mucosal cultures.
American journal of veterinary research Jun, 2006 | Pubmed ID: 16740101
Females remyelinate more efficiently than males following demyelination in the aged but not young adult CNS.
Experimental neurology Nov, 2006 | Pubmed ID: 16797535
Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells.
Glia Sep, 2006 | Pubmed ID: 16856149
Cdc42 and Rac1 signaling are both required for and act synergistically in the correct formation of myelin sheaths in the CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2006 | Pubmed ID: 17021167
Calponin is expressed by fibroblasts and meningeal cells but not olfactory ensheathing cells in the adult peripheral olfactory system.
Glia Jan, 2007 | Pubmed ID: 17078028
Mutations in genes causing human familial isolated hyperparathyroidism do not account for hyperparathyroidism in Keeshond dogs.
Veterinary journal (London, England : 1997) Nov, 2007 | Pubmed ID: 17158076
Myelin repair: the role of stem and precursor cells in multiple sclerosis.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Jan, 2008 | Pubmed ID: 17282989
Myelin regeneration in demyelinating disorders: new developments in biology and clinical pathology.
Current opinion in neurology Jun, 2007 | Pubmed ID: 17495623
Promoting remyelination in multiple sclerosis by endogenous adult neural stem/precursor cells: defining cellular targets.
Journal of the neurological sciences Feb, 2008 | Pubmed ID: 17570402
Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development.
The Journal of cell biology Jun, 2007 | Pubmed ID: 17576798
Development of a universal measure of quadrupedal forelimb-hindlimb coordination using digital motion capture and computerised analysis.
BMC neuroscience Sep, 2007 | Pubmed ID: 17877823
Contrasting effects of basic fibroblast growth factor and epidermal growth factor on mouse neonatal olfactory mucosa cells.
The European journal of neuroscience Dec, 2007 | Pubmed ID: 18088275
The biology of CNS remyelination: the key to therapeutic advances.
Journal of neurology Mar, 2008 | Pubmed ID: 18317673
Serum-free medium provides a clinically relevant method to increase olfactory ensheathing cell numbers in olfactory mucosa cell culture.
Cell transplantation , 2008 | Pubmed ID: 18351018
Taking ageing into account in remyelination-based therapies for multiple sclerosis.
Journal of the neurological sciences Nov, 2008 | Pubmed ID: 18539300
Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination.
Neurobiology of disease Aug, 2008 | Pubmed ID: 18539470
An experimental model of secondary progressive multiple sclerosis that shows regional variation in gliosis, remyelination, axonal and neuronal loss.
Journal of neuroimmunology Sep, 2008 | Pubmed ID: 18672298
Remyelination in the CNS: from biology to therapy.
Nature reviews. Neuroscience Nov, 2008 | Pubmed ID: 18931697
Quantification of deficits in lateral paw positioning after spinal cord injury in dogs.
BMC veterinary research Nov, 2008 | Pubmed ID: 19032742
Zebrafish myelination: a transparent model for remyelination?
Disease models & mechanisms , 2008 | Pubmed ID: 19093028
Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency.
Nature neuroscience Sep, 2008 | Pubmed ID: 19160500
Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling.
Brain : a journal of neurology Feb, 2009 | Pubmed ID: 19208690
Transplanted oligodendrocyte precursor cells reduce neurodegeneration in a model of glaucoma.
Investigative ophthalmology & visual science Sep, 2009 | Pubmed ID: 19357352
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS.
Genes & development Jul, 2009 | Pubmed ID: 19515974
Remyelination - An effective means of neuroprotection.
Hormones and behavior Jan, 2010 | Pubmed ID: 19538961
Up-regulation of oligodendrocyte precursor cell alphaV integrin and its extracellular ligands during central nervous system remyelination.
Journal of neuroscience research Nov, 2009 | Pubmed ID: 19739252
Temporal dynamics of myelination in the zebrafish spinal cord.
Glia May, 2010 | Pubmed ID: 20140960
FGF but not EGF induces phosphorylation of the cAMP response element binding protein in olfactory mucosa-derived cell cultures.
Experimental cell research May, 2010 | Pubmed ID: 20211167
Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects.
Neuropharmacology Sep, 2010 | Pubmed ID: 20450924
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.
Cell stem cell Jun, 2010 | Pubmed ID: 20569695
Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy.
Journal of biomechanics Nov, 2010 | Pubmed ID: 20656292
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination.
Annals of neurology Nov, 2010 | Pubmed ID: 20853437
Retinoid X receptor gamma signaling accelerates CNS remyelination.
Nature neuroscience Jan, 2011 | Pubmed ID: 21131950
Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2011 | Pubmed ID: 21248132
Regenerative medicine in multiple sclerosis: identifying pharmacological targets of adult neural stem cell differentiation.
Neurochemistry international Sep, 2011 | Pubmed ID: 21300122
Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis.
Brain : a journal of neurology Jul, 2011 | Pubmed ID: 21705418
Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination.
Nature neuroscience Jun, 2011 | Pubmed ID: 21706018
Myelin regeneration in multiple sclerosis: targeting endogenous stem cells.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics Oct, 2011 | Pubmed ID: 21904791
Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2012 | Pubmed ID: 22160722
Rejuvenation of regeneration in the aging central nervous system.
Cell stem cell Jan, 2012 | Pubmed ID: 22226359
Mechanical environment modulates biological properties of oligodendrocyte progenitor cells.
Stem cells and development Nov, 2012 | Pubmed ID: 22646081
Accelerated axonal loss following acute CNS demyelination in mice lacking protein tyrosine phosphatase receptor type Z.
The American journal of pathology Nov, 2012 | Pubmed ID: 22940073
Neuroprotection and repair in multiple sclerosis.
Nature reviews. Neurology Nov, 2012 | Pubmed ID: 23026979
Embryonic-derived olfactory ensheathing cells remyelinate focal areas of spinal cord demyelination more efficiently than neonatal or adult-derived cells.
Cell transplantation , 2013 | Pubmed ID: 23031825
Autologous olfactory mucosal cell transplants in clinical spinal cord injury: a randomized double-blinded trial in a canine translational model.
Brain : a journal of neurology Nov, 2012 | Pubmed ID: 23169917
Current status of myelin replacement therapies in multiple sclerosis.
Progress in brain research , 2012 | Pubmed ID: 23186717
Do your glial cells make you clever?
Cell stem cell Mar, 2013 | Pubmed ID: 23472865
Identification of endothelin 2 as an inflammatory factor that promotes central nervous system remyelination.
Brain : a journal of neurology Apr, 2013 | Pubmed ID: 23518706
Myokymia and neuromyotonia in veterinary medicine: a comparison with peripheral nerve hyperexcitability syndrome in humans.
Veterinary journal (London, England : 1997) Aug, 2013 | Pubmed ID: 23583699
Neural precursor cells cultured at physiologically relevant oxygen tensions have a survival advantage following transplantation.
Stem cells translational medicine Jun, 2013 | Pubmed ID: 23677643
Ageing stem and progenitor cells: implications for rejuvenation of the central nervous system.
Development (Cambridge, England) Jun, 2013 | Pubmed ID: 23715549
Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis.
The European journal of neuroscience Sep, 2013 | Pubmed ID: 23763823
The late response of rat subependymal zone stem and progenitor cells to stroke is restricted to directly affected areas of their niche.
Experimental neurology Oct, 2013 | Pubmed ID: 23830949
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination.
Nature neuroscience Sep, 2013 | Pubmed ID: 23872599
Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination.
EMBO molecular medicine Dec, 2013 | Pubmed ID: 24293318
Neuregulin and BDNF induce a switch to NMDA receptor-dependent myelination by oligodendrocytes.
PLoS biology Dec, 2013 | Pubmed ID: 24391468
Cell therapy for spinal cord injuries: what is really going on?
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry Dec, 2014 | Pubmed ID: 24415275
The translational biology of remyelination: past, present, and future.
Glia Nov, 2014 | Pubmed ID: 24446279
Auxetic nuclei in embryonic stem cells exiting pluripotency.
Nature materials Jun, 2014 | Pubmed ID: 24747782
Multiple sclerosis genetics.
The Lancet. Neurology Jul, 2014 | Pubmed ID: 24852507
Special issue on stem cells: "the end of the beginning".
Experimental neurology Oct, 2014 | Pubmed ID: 24950181
Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.
Nature medicine Aug, 2014 | Pubmed ID: 24997607
Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression.
Nature communications Jul, 2014 | Pubmed ID: 25014177
The EIIIA domain from astrocyte-derived fibronectin mediates proliferation of oligodendrocyte progenitor cells following CNS demyelination.
Glia Feb, 2015 | Pubmed ID: 25156142
Demyelination causes adult CNS progenitors to revert to an immature state and express immune cues that support their migration.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jan, 2015 | Pubmed ID: 25568099
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells.
Experimental neurology Jul, 2015 | Pubmed ID: 25819103
The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience Apr, 2015 | Pubmed ID: 25904802
Fibroblast growth factor signaling in oligodendrocyte-lineage cells facilitates recovery of chronically demyelinated lesions but is redundant in acute lesions.
Glia Oct, 2015 | Pubmed ID: 25913734
Glia Disease and Repair-Remyelination.
Cold Spring Harbor perspectives in biology May, 2015 | Pubmed ID: 25986556
Regenerative Medicines for Remyelination: From Aspiration to Reality.
Cell stem cell Jun, 2015 | Pubmed ID: 26046755
Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell Remyelination.
The American journal of pathology Sep, 2015 | Pubmed ID: 26193667
Sox2 Sustains Recruitment of Oligodendrocyte Progenitor Cells following CNS Demyelination and Primes Them for Differentiation during Remyelination.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2015 | Pubmed ID: 26290228
Discovery of a novel neuroprotectant, BHDPC, that protects against MPP+/MPTP-induced neuronal death in multiple experimental models.
Free radical biology & medicine Dec, 2015 | Pubmed ID: 26415025
Neuronal activity regulates remyelination via glutamate signalling to oligodendrocyte progenitors.
Nature communications Oct, 2015 | Pubmed ID: 26439639
Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.
Brain : a journal of neurology Dec, 2015 | Pubmed ID: 26463675
Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation.
Glia Mar, 2016 | Pubmed ID: 26576485
Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation.
The Journal of cell biology Dec, 2015 | Pubmed ID: 26644513
Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta neuropathologica Feb, 2016 | Pubmed ID: 26687980
Pioglitazone regulates myelin phagocytosis and multiple sclerosis monocytes.
Annals of clinical and translational neurology Dec, 2015 | Pubmed ID: 26734659
Pre-Existing Mature Oligodendrocytes Do Not Contribute to Remyelination following Toxin-Induced Spinal Cord Demyelination.
The American journal of pathology Mar, 2016 | Pubmed ID: 26773350
Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage.
Cell reports Apr, 2016 | Pubmed ID: 27149841
Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline.
Cell reports Apr, 2016 | Pubmed ID: 27149850
Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta neuropathologica Jul, 2016 | Pubmed ID: 27161252
CNS Remyelination and the Innate Immune System.
Frontiers in cell and developmental biology , 2016 | Pubmed ID: 27200350
Axonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy.
Acta neuropathologica communications Aug, 2016 | Pubmed ID: 27552807
Electric Signals Regulate the Directional Migration of Oligodendrocyte Progenitor Cells (OPCs) via β1 Integrin.
International journal of molecular sciences Nov, 2016 | Pubmed ID: 27879672
MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter.
Nature biotechnology Dec, 2016 | Pubmed ID: 27918546
Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2016 | Pubmed ID: 27930320
Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice.
Stem cell reports Mar, 2017 | Pubmed ID: 28196689
Regulatory T cells promote myelin regeneration in the central nervous system.
Nature neuroscience May, 2017 | Pubmed ID: 28288125
Efficient Remyelination Requires DNA Methylation.
eNeuro , 2017 | Pubmed ID: 28451635
Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination.
Acta neuropathologica Jul, 2017 | Pubmed ID: 28484846
Recruitment of endogenous CNS stem cells for regeneration in demyelinating disease.
Progress in brain research , 2017 | Pubmed ID: 28554395
Do Not Adjust Your Mind: The Fault Is in Your Glia.
Cell stem cell Aug, 2017 | Pubmed ID: 28777939
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination.
Cell reports Aug, 2017 | Pubmed ID: 28834740
Serum-Free Medium Provides a Clinically Relevant Method to Increase Olfactory Ensheathing Cell Numbers in Olfactory Mucosa Cell Culture.
Cell transplantation Nov, 2007 | Pubmed ID: 28866922
Regenerating CNS myelin - from mechanisms to experimental medicines.
Nature reviews. Neuroscience Nov, 2017 | Pubmed ID: 29142295
Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury.
Brain : a journal of neurology 01, 2018 | Pubmed ID: 29244098
A Subpopulation of Foxj1-Expressing, Nonmyelinating Schwann Cells of the Peripheral Nervous System Contribute to Schwann Cell Remyelination in the Central Nervous System.
The Journal of neuroscience : the official journal of the Society for Neuroscience Oct, 2018 | Pubmed ID: 30228229
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Immunity Jan, 2019 | Pubmed ID: 30471926
Toxin-Based Models to Investigate Demyelination and Remyelination.
Methods in molecular biology (Clifton, N.J.) , 2019 | Pubmed ID: 30820910
Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitors.
Glia Jul, 2019 | Pubmed ID: 30861188
SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke.
EBioMedicine Apr, 2019 | Pubmed ID: 30905846
Diversity in the oligodendrocyte lineage: Plasticity or heterogeneity?
Glia Oct, 2019 | Pubmed ID: 30968471
Pericytes Favor Oligodendrocyte Fate Choice in Adult Neural Stem Cells.
Frontiers in cellular neuroscience , 2019 | Pubmed ID: 30971893
Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.
Glia Aug, 2019 | Pubmed ID: 31038798
Neuronal vulnerability and multilineage diversity in multiple sclerosis.
Nature Sep, 2019 | Pubmed ID: 31316211
Niche stiffness underlies the ageing of central nervous system progenitor cells.
Nature Sep, 2019 | Pubmed ID: 31413369
Author Correction: Niche stiffness underlies the ageing of central nervous system progenitor cells.
Nature Sep, 2019 | Pubmed ID: 31462780
Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells.
Cell stem cell Oct, 2019 | Pubmed ID: 31585093
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.
Cell stem cell Oct, 2019 | Pubmed ID: 31585094
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2019 | Pubmed ID: 31740610
Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration.
Neuron Mar, 2020 | Pubmed ID: 31924446
The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelination.
Glia Jul, 2020 | Pubmed ID: 32017258
Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system.
Acta neuropathologica May, 2020 | Pubmed ID: 32030468
Correction to: Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system.
Acta neuropathologica May, 2020 | Pubmed ID: 32211925
Problems and Pitfalls of Identifying Remyelination in Multiple Sclerosis.
Cell stem cell May, 2020 | Pubmed ID: 32386552
Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing.
Molecular & cellular proteomics : MCP Aug, 2020 | Pubmed ID: 32434922
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis.
Acta neuropathologica Aug, 2020 | Pubmed ID: 32572598
The Role of Astrocytes in Remyelination.
Trends in neurosciences Aug, 2020 | Pubmed ID: 32620289
Revisiting remyelination: Towards a consensus on the regeneration of CNS myelin.
Seminars in cell & developmental biology Aug, 2021 | Pubmed ID: 33082115
Schwann cell remyelination of the central nervous system: why does it happen and what are the benefits?
Open biology Jan, 2021 | Pubmed ID: 33497588
Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes.
Nature genetics Mar, 2021 | Pubmed ID: 33589840
Author Correction: Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes.
Nature genetics Apr, 2021 | Pubmed ID: 33637963
Neuroprotective effects of Sonic hedgehog agonist SAG in a rat model of neonatal stroke.
Pediatric research Dec, 2021 | Pubmed ID: 33654279
A map of transcriptional heterogeneity and regulatory variation in human microglia.
Nature genetics Jun, 2021 | Pubmed ID: 34083789
Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.
Cell reports Jul, 2021 | Pubmed ID: 34260928
Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity?
Frontiers in cellular neuroscience , 2021 | Pubmed ID: 34381334
Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study.
The Lancet. Neurology Sep, 2021 | Pubmed ID: 34418398
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.
Nature neuroscience Mar, 2022 | Pubmed ID: 35260865
Remyelination in humans due to a retinoid-X receptor agonist is age-dependent.
Annals of clinical and translational neurology Jul, 2022 | Pubmed ID: 35587315
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis.
Neuropathology and applied neurobiology Feb, 2023 | Pubmed ID: 36181265
Ageing and multiple sclerosis.
The Lancet. Neurology Jan, 2023 | Pubmed ID: 36216015
CNS remyelination and inflammation: From basic mechanisms to therapeutic opportunities.
Neuron Nov, 2022 | Pubmed ID: 36228613
Cell-free DNA-based liquid biopsies in neurology.
Brain : a journal of neurology May, 2023 | Pubmed ID: 36408894
SARM1 detection in myelinating glia: / is dispensable for PNS and CNS myelination in zebrafish and mice.
Frontiers in cellular neuroscience , 2023 | Pubmed ID: 37091921
Myc determines the functional age state of oligodendrocyte progenitor cells.
Nature aging Sep, 2021 | Pubmed ID: 37117631
Targeted evolution of adeno-associated virus capsids for systemic transgene delivery to microglia and tissue-resident macrophages.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2023 | Pubmed ID: 37603759
Remyelination in the Central Nervous System.
Cold Spring Harbor perspectives in biology Feb, 2024 | Pubmed ID: 38316552
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