Department of Immunology and Biotherapy,
National Clinical Research Center for Cancer,
Tianjin's Clinical Research Center for Cancer,
Key Laboratory of Cancer Immunology and Biotherapy,
Key Laboratory of Cancer Prevention and Therapy,
Department of Immunology and Biotherapy, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Immunology and Biotherapy, Key Laboratory of Cancer Prevention and Therapy
Prof.Ren's main research area is in the human movement science
Anti-CD47 Antibody As a Targeted Therapeutic Agent for Human Lung Cancer and Cancer Stem Cells.
Frontiers in immunology , 2017 | Pubmed ID: 28484448
Quality of Life after Autologous Peripheral Blood Stem Cell Transplantation and High-Dose Chemotherapy in High-Risk Breast Cancer Patients.
Breast care (Basel, Switzerland) , 2009 | Pubmed ID: 20877673
Increased prevalence of regulatory T cells in the lung cancer microenvironment: a role of thymic stromal lymphopoietin.
Cancer immunology, immunotherapy : CII Nov, 2011 | Pubmed ID: 21681373
Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells.
Journal of experimental & clinical cancer research : CR Sep, 2011 | Pubmed ID: 21917155
Therapeutic effect of intratumoral administration of DCs with conditional expression of combination of different cytokines.
Cancer immunology, immunotherapy : CII Apr, 2012 | Pubmed ID: 22223258
Enhanced activation of human dendritic cells by silencing SOCS1 and activating TLRs simultaneously.
Cancer immunology, immunotherapy : CII Oct, 2012 | Pubmed ID: 22366886
Autologous cytokine-induced killer cell immunotherapy in lung cancer: a phase II clinical study.
Cancer immunology, immunotherapy : CII May, 2012 | Pubmed ID: 22581306
Autophagy induced by conventional chemotherapy mediates tumor cell sensitivity to immunotherapy.
Cancer research Nov, 2012 | Pubmed ID: 22942258
Over-expression of semaphorin4D, hypoxia-inducible factor-1α and vascular endothelial growth factor is related to poor prognosis in ovarian epithelial cancer.
International journal of molecular sciences Oct, 2012 | Pubmed ID: 23202951
Combining the negative lymph nodes count with the ratio of positive and removed lymph nodes can better predict the postoperative survival in cervical cancer patients.
Cancer cell international Feb, 2013 | Pubmed ID: 23374254
Dysfunctional activation of neurotensin/IL-8 pathway in hepatocellular carcinoma is associated with increased inflammatory response in microenvironment, more epithelial mesenchymal transition in cancer and worse prognosis in patients.
PloS one , 2013 | Pubmed ID: 23418512
Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer.
Journal of immunology (Baltimore, Md. : 1950) Apr, 2013 | Pubmed ID: 23440412
Current adoptive immunotherapy in non-small cell lung cancer and potential influence of therapy outcome.
Cancer investigation Mar, 2013 | Pubmed ID: 23477587
Clinical implication of microrna for lung cancer.
Cancer biotherapy & radiopharmaceuticals May, 2013 | Pubmed ID: 23496233
A phase II, randomized, double-blind, placebo-controlled multicenter trial of Endostar in patients with metastatic melanoma.
Molecular therapy : the journal of the American Society of Gene Therapy Jul, 2013 | Pubmed ID: 23670576
The correlation between the subsets of tumor infiltrating memory T cells and the expression of indoleamine 2,3-dioxygenase in gastric cancer.
Digestive diseases and sciences Dec, 2013 | Pubmed ID: 23979437
Diagnostic and prognostic value of circulating miR-21 for cancer: a systematic review and meta-analysis.
Gene Jan, 2014 | Pubmed ID: 24076132
The role of phosphoglycerate mutase 1 in tumor aerobic glycolysis and its potential therapeutic implications.
International journal of cancer Nov, 2014 | Pubmed ID: 24285383
Can the dual-functional capability of CIK cells be used to improve antitumor effects?
Cellular immunology Jan, 2014 | Pubmed ID: 24355711
Primary hepatic angiosarcoma and potential treatment options.
Journal of gastroenterology and hepatology May, 2014 | Pubmed ID: 24372769
Activation of the epidermal growth factor receptor in macrophages regulates cytokine production and experimental colitis.
Journal of immunology (Baltimore, Md. : 1950) Feb, 2014 | Pubmed ID: 24391216
Maintenance therapy with autologous cytokine-induced killer cells in patients with advanced epithelial ovarian cancer after first-line treatment.
Journal of immunotherapy (Hagerstown, Md. : 1997) , 2014 | Pubmed ID: 24509174
Cancer immunoinformatics: a new assistant tool for malignant disease research.
Chinese medical journal , 2014 | Pubmed ID: 24622449
Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis.
Cancer cell Apr, 2014 | Pubmed ID: 24735924
The subsets of dendritic cells and memory T cells correspond to indoleamine 2,3-dioxygenase in stomach tumor microenvironment.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Sep, 2014 | Pubmed ID: 24870595
Macrophage immunomodulation by breast cancer-derived exosomes requires Toll-like receptor 2-mediated activation of NF-κB.
Scientific reports Jul, 2014 | Pubmed ID: 25034888
Noncanonical NF-κB activation mediates STAT3-stimulated IDO upregulation in myeloid-derived suppressor cells in breast cancer.
Journal of immunology (Baltimore, Md. : 1950) Sep, 2014 | Pubmed ID: 25063873
TGFβ induces "BRCAness" and sensitivity to PARP inhibition in breast cancer by regulating DNA-repair genes.
Molecular cancer research : MCR Nov, 2014 | Pubmed ID: 25103497
Pemetrexed-based chemotherapy in advanced lung adenocarcinoma patients with different EGFR genotypes.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Feb, 2015 | Pubmed ID: 25301443
The hOGG1 Ser326Cys polymorphism contributes to digestive system cancer susceptibility: evidence from 48 case-control studies.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Feb, 2015 | Pubmed ID: 25323581
Osteopontin is a novel prognostic biomarker in early-stage non-small cell lung cancer after surgical resection.
Journal of cancer research and clinical oncology Aug, 2015 | Pubmed ID: 25555465
Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis.
Nature cell biology Feb, 2015 | Pubmed ID: 25621950
Matrix metalloproteinase 13: a potential intermediate between low expression of microRNA-125b and increasing metastatic potential of non-small cell lung cancer.
Cancer genetics Mar, 2015 | Pubmed ID: 25772251
Highlights on mechanisms of drugs targeting MDSCs: providing a novel perspective on cancer treatment.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine May, 2015 | Pubmed ID: 25828146
Long non-coding RNA HOTAIR promotes tumor cell invasion and metastasis by recruiting EZH2 and repressing E-cadherin in oral squamous cell carcinoma.
International journal of oncology , 2015 | Pubmed ID: 25901533
High-mobility group nucleosome-binding protein 1 is a novel clinical biomarker in non-small cell lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Dec, 2015 | Pubmed ID: 26113410
Role of microRNA-150 in solid tumors.
Oncology letters Jul, 2015 | Pubmed ID: 26170969
Regulatory B cell: New member of immunosuppressive cell club.
Human immunology Sep, 2015 | Pubmed ID: 26385479
The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications.
Oncotarget Dec, 2015 | Pubmed ID: 26460955
IL-8, a novel messenger to cross-link inflammation and tumor EMT via autocrine and paracrine pathways (Review).
International journal of oncology Jan, 2016 | Pubmed ID: 26548401
Digital Karyotyping with Whole Genomic Sequencing for Complex Congenital Disorder.
Journal of genetics and genomics = Yi chuan xue bao Nov, 2015 | Pubmed ID: 26674382
Knock-down of CIAPIN1 sensitizes K562 chronic myeloid leukemia cells to Imatinib by regulation of cell cycle and apoptosis-associated members via NF-κB and ERK5 signaling pathway.
Biochemical pharmacology Jan, 2016 | Pubmed ID: 26679828
Human umbilical cord mesenchymal stem cells delivering sTRAIL home to lung cancer mediated by MCP-1/CCR2 axis and exhibit antitumor effects.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Jun, 2016 | Pubmed ID: 26733169
Rapid Response of Advanced Squamous Non-Small Cell Lung Cancer with Thrombocytopenia after First-Line Treatment with Pembrolizumab Plus Autologous Cytokine-Induced Killer Cells.
Frontiers in immunology , 2015 | Pubmed ID: 26734004
HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research Aug, 2016 | Pubmed ID: 26964571
Identification of a three-miRNA signature as a blood-borne diagnostic marker for early diagnosis of lung adenocarcinoma.
Oncotarget May, 2016 | Pubmed ID: 27036025
Autologous Cytokine-Induced Killer Cells Improves Overall Survival of Metastatic Colorectal Cancer Patients: Results From a Phase II Clinical Trial.
Clinical colorectal cancer Sep, 2016 | Pubmed ID: 27052743
[Analysis of the Role of PET/CT SUVmax in Prognosis and Its Correlation with Clinicopathological Characteristics in Resectable Lung Squamous Cell Carcinoma].
Zhongguo fei ai za zhi = Chinese journal of lung cancer Apr, 2016 | Pubmed ID: 27118646
A clinically relevant in vivo zebrafish model of human multiple myeloma to study preclinical therapeutic efficacy.
Blood Jul, 2016 | Pubmed ID: 27207793
Soluble Toll-like receptor 4 is a potential serum biomarker in non-small cell lung cancer.
Oncotarget Jun, 2016 | Pubmed ID: 27223258
Adoptive Cellular Therapy (ACT) for Cancer Treatment.
Advances in experimental medicine and biology , 2016 | Pubmed ID: 27240459
Profiling the dynamic expression of checkpoint molecules on cytokine-induced killer cells from non-small-cell lung cancer patients.
Oncotarget Jul, 2016 | Pubmed ID: 27283895
Positive and negative functions of B lymphocytes in tumors.
Oncotarget Aug, 2016 | Pubmed ID: 27331871
An LGG-derived protein promotes IgA production through upregulation of APRIL expression in intestinal epithelial cells.
Mucosal immunology Mar, 2017 | Pubmed ID: 27353252
Relationship of VEGF/VEGFR with immune and cancer cells: staggering or forward?
Cancer biology & medicine Jun, 2016 | Pubmed ID: 27458528
Plasma miR-324-3p and miR-1285 as diagnostic and prognostic biomarkers for early stage lung squamous cell carcinoma.
Oncotarget Sep, 2016 | Pubmed ID: 27517633
BMP signaling and its paradoxical effects in tumorigenesis and dissemination.
Oncotarget Nov, 2016 | Pubmed ID: 27661009
Rack1 Mediates the Interaction of P-Glycoprotein with Anxa2 and Regulates Migration and Invasion of Multidrug-Resistant Breast Cancer Cells.
International journal of molecular sciences Oct, 2016 | Pubmed ID: 27754360
Effects of ulinastatin on early postoperative cognitive function after one-lung ventilation surgery in elderly patients receiving neoadjuvant chemotherapy.
Metabolic brain disease Apr, 2017 | Pubmed ID: 27830357
Indoleamine 2,3-dioxygenase regulates T cell activity through Vav1/Rac pathway.
Molecular immunology Jan, 2017 | Pubmed ID: 27930920
Dysregulation of CUL4A and CUL4B Ubiquitin Ligases in Lung Cancer.
The Journal of biological chemistry Feb, 2017 | Pubmed ID: 27974468
Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis.
PloS one , 2017 | Pubmed ID: 28135282
[Progress of PD-1/PD-L1 Inhibitors in Non-small Cell Lung Cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer Feb, 2017 | Pubmed ID: 28228226
Highlights on immune checkpoint inhibitors in non-small cell lung cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Mar, 2017 | Pubmed ID: 28349816
Efficacy of ALK5 inhibition in myelofibrosis.
JCI insight Apr, 2017 | Pubmed ID: 28405618
Expression of TLR4 in Non-Small Cell Lung Cancer Is Associated with PD-L1 and Poor Prognosis in Patients Receiving Pulmonectomy.
Frontiers in immunology , 2017 | Pubmed ID: 28484456
Prognostic value of pretreatment inflammatory biomarkers in advanced lung adenocarcinoma patients receiving first-line pemetrexed/platinum doublet.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Jun, 2017 | Pubmed ID: 28618954
Concurrent somatic mutations in driver genes were significantly correlated with lymph node metastasis and pathological types in solid tumors.
Oncotarget Sep, 2017 | Pubmed ID: 28978153
The role of toll-like receptor 4 in tumor microenvironment.
Oncotarget Sep, 2017 | Pubmed ID: 29029545
Ginsenoside Rg3 attenuates cisplatin resistance in lung cancer by downregulating PD-L1 and resuming immune.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Dec, 2017 | Pubmed ID: 29031195
Cytokine-Induced Killer Cells Modulates Resistance to Cisplatin in the A549/DDP Cell Line.
Journal of Cancer , 2017 | Pubmed ID: 29158802
Herceptin Enhances the Antitumor Effect of Natural Killer Cells on Breast Cancer Cells Expressing Human Epidermal Growth Factor Receptor-2.
Frontiers in immunology , 2017 | Pubmed ID: 29163501
[Efficacy and Survival Analysis of Apatinib in Patients with Advanced Nonsquamous Non-small Cell Lung Cancer after Failure of First-line Treatment].
Zhongguo fei ai za zhi = Chinese journal of lung cancer Nov, 2017 | Pubmed ID: 29167006
Interleukin-6 -Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Suppressor Cells Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer.
Frontiers in immunology , 2017 | Pubmed ID: 29326716
Phosphoglyceric acid mutase-1 contributes to oncogenic mTOR-mediated tumor growth and confers non-small cell lung cancer patients with poor prognosis.
Cell death and differentiation Jun, 2018 | Pubmed ID: 29362480
MicroRNA-544 promotes colorectal cancer progression by targeting forkhead box O1.
Oncology letters Jan, 2018 | Pubmed ID: 29422969
Chemotherapy Induces Breast Cancer Stemness in Association with Dysregulated Monocytosis.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2018 | Pubmed ID: 29500278
New Insights into Tumor-Infiltrating B Lymphocytes in Breast Cancer: Clinical Impacts and Regulatory Mechanisms.
Frontiers in immunology , 2018 | Pubmed ID: 29568299
A novel MDSC-induced PD-1PD-L1 B-cell subset in breast tumor microenvironment possesses immuno-suppressive properties.
Oncoimmunology , 2018 | Pubmed ID: 29632731
Cancer-cell-secreted exosomal miR-105 promotes tumour growth through the MYC-dependent metabolic reprogramming of stromal cells.
Nature cell biology May, 2018 | Pubmed ID: 29662176
High Indoleamine 2,3-Dioxygenase Is Correlated With Microvessel Density and Worse Prognosis in Breast Cancer.
Frontiers in immunology , 2018 | Pubmed ID: 29719533
New insights into the biological impacts of immune cell-derived exosomes within the tumor environment.
Cancer letters Sep, 2018 | Pubmed ID: 29857125
Efficiency of Cytokine-Induced Killer Cells in Combination with Chemotherapy for Triple-Negative Breast Cancer.
Journal of breast cancer Jun, 2018 | Pubmed ID: 29963110
Prognostic Significance of BCL-2 and BCL-6 Expression in MYC-positive DLBCL.
Clinical lymphoma, myeloma & leukemia Oct, 2018 | Pubmed ID: 29983382
A new perspective: Exploring future therapeutic strategies for cancer by understanding the dual role of B lymphocytes in tumor immunity.
International journal of cancer Jun, 2019 | Pubmed ID: 30183084
PD-1/PD-L1 Axis, Rather Than High-Mobility Group Alarmins or CD8+ Tumor-Infiltrating Lymphocytes, Is Associated With Survival in Head and Neck Squamous Cell Carcinoma Patients Who Received Surgical Resection.
Frontiers in oncology , 2018 | Pubmed ID: 30619746
Diprophylline inhibits non-small cell lung cancer A549 cell proliferation and migration, and promotes apoptosis, by downregulating PI3K signaling pathway.
Oncology letters Jan, 2019 | Pubmed ID: 30655839
Tumor CD73/A2aR adenosine immunosuppressive axis and tumor-infiltrating lymphocytes in diffuse large B-cell lymphoma: correlations with clinicopathological characteristics and clinical outcome.
International journal of cancer Sep, 2019 | Pubmed ID: 30664812
Clinical Significance of Serum Type III Interferons in Patients with Gastric Cancer.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research Mar, 2019 | Pubmed ID: 30672717
Chemoradiotherapy-Induced CD4 and CD8 T-Cell Alterations to Predict Patient Outcomes in Esophageal Squamous Cell Carcinoma.
Frontiers in oncology , 2019 | Pubmed ID: 30828566
Anlotinib Versus Sunitinib as First-Line Treatment for Metastatic Renal Cell Carcinoma: A Randomized Phase II Clinical Trial.
The oncologist 08, 2019 | Pubmed ID: 30902918
Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis.
Frontiers in oncology , 2019 | Pubmed ID: 31024840
Plasma soluble programmed death ligand 1 levels predict clinical response in peripheral T-cell lymphomas.
Hematological oncology Aug, 2019 | Pubmed ID: 31074879
Chemotherapy-Induced Extracellular Vesicle miRNAs Promote Breast Cancer Stemness by Targeting .
Cancer research Jul, 2019 | Pubmed ID: 31118200
Memory stem T cells generated by Wnt signaling from blood of human renal clear cell carcinoma patients.
Cancer biology & medicine Feb, 2019 | Pubmed ID: 31119051
Nicotine promotes the development of non-small cell lung cancer through activating LINC00460 and PI3K/Akt signaling.
Bioscience reports Jun, 2019 | Pubmed ID: 31123168
Diagnostic value of ProGRP for small cell lung cancer in different stages.
Journal of thoracic disease Apr, 2019 | Pubmed ID: 31179060
Prognostic Value of the Neo-Immunoscore in Renal Cell Carcinoma.
Frontiers in oncology , 2019 | Pubmed ID: 31192136
T-cell receptor gene therapy targeting melanoma-associated antigen-A4 by silencing of endogenous TCR inhibits tumor growth in mice and human.
Cell death & disease Jun, 2019 | Pubmed ID: 31209257
LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY.
Cancer research Sep, 2019 | Pubmed ID: 31289132
New insight on the correlation of metabolic status on F-FDG PET/CT with immune marker expression in patients with non-small cell lung cancer.
European journal of nuclear medicine and molecular imaging May, 2020 | Pubmed ID: 31502013
Factors related to rapid progression of non-small cell lung cancer in Chinese patients treated using single-agent immune checkpoint inhibitor treatment.
Thoracic cancer May, 2020 | Pubmed ID: 32134200
An open label, multicenter, noninterventional study of apatinib in advanced gastric cancer patients (AHEAD-G202).
Therapeutic advances in medical oncology , 2020 | Pubmed ID: 32218807
Safety and effectiveness of apatinib in patients with previously treated metastatic gastric cancer: a sub-analysis from the real-world study of apatinib for gastric cancer treatment (AHEAD-G202).
American journal of cancer research , 2020 | Pubmed ID: 32266105
Prognosis significance of indoleamine 2, 3-dioxygenase, programmed death ligand-1 and tumor-infiltrating immune cells in microenvironment of breast cancer.
International immunopharmacology Jul, 2020 | Pubmed ID: 32330866
Anlotinib for Patients With Metastatic Renal Cell Carcinoma Previously Treated With One Vascular Endothelial Growth Factor Receptor-Tyrosine Kinase Inhibitor: A Phase 2 Trial.
Frontiers in oncology , 2020 | Pubmed ID: 32457838
Primary tumor standardized uptake value (SUVmax) measured on F-FDG PET/CT and mixed NSCLC components predict survival in surgical-resected combined small-cell lung cancer.
Journal of cancer research and clinical oncology Oct, 2020 | Pubmed ID: 32494919
Chromosome Abnormalities: New Insights into Their Clinical Significance in Cancer.
Molecular therapy oncolytics Jun, 2020 | Pubmed ID: 32637574
Feasibility of sleeve lobectomy after neo-adjuvant chemo-immunotherapy in non-small cell lung cancer.
Translational lung cancer research Jun, 2020 | Pubmed ID: 32676337
Efficacy and Safety of Sintilimab Plus Pemetrexed and Platinum as First-Line Treatment for Locally Advanced or Metastatic Nonsquamous NSCLC: a Randomized, Double-Blind, Phase 3 Study (Oncology pRogram by InnovENT anti-PD-1-11).
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 10, 2020 | Pubmed ID: 32781263
Expression level of PD-L1 is involved in ALDH1A1-mediated poor prognosis in patients with head and neck squamous cell carcinoma.
Pathology, research and practice Sep, 2020 | Pubmed ID: 32825960
Expression signature, prognosis value, and immune characteristics of Siglec-15 identified by pan-cancer analysis.
Oncoimmunology Aug, 2020 | Pubmed ID: 32939323
Comprehensive insights into the effects and regulatory mechanisms of immune cells expressing programmed death-1/programmed death ligand 1 in solid tumors.
Cancer biology & medicine Aug, 2020 | Pubmed ID: 32944395
The Clinical Significance of SIRT2 in Malignancies: A Tumor Suppressor or an Oncogene?
Frontiers in oncology , 2020 | Pubmed ID: 33014852
Randomized, multicenter, open-label trial of autologous cytokine-induced killer cell immunotherapy plus chemotherapy for squamous non-small-cell lung cancer: NCT01631357.
Signal transduction and targeted therapy Oct, 2020 | Pubmed ID: 33077722
Significantly different immunological score in lung adenocarcinoma and squamous cell carcinoma and a proposal for a new immune staging system.
Oncoimmunology , 2020 | Pubmed ID: 33101777
Plasma soluble PD-L1 and STAT3 predict the prognosis in diffuse large B cell lymphoma patients.
Journal of Cancer , 2020 | Pubmed ID: 33123290
Autologous cytokine-induced killer (CIK) cells enhance the clinical response to PD-1 blocking antibodies in patients with advanced non-small cell lung cancer: A preliminary study.
Thoracic cancer Jan, 2021 | Pubmed ID: 33150733
Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3 CD8 T Cells and Survival in Diffuse Large B Cell Lymphoma.
Journal of immunology research , 2020 | Pubmed ID: 33178839
Exhausted T cells and epigenetic status.
Cancer biology & medicine Nov, 2020 | Pubmed ID: 33299644
Efficacy and safety of apatinib for the treatment of AFP-producing gastric cancer.
Translational oncology Feb, 2021 | Pubmed ID: 33383486
Consistency of genotyping data from simultaneously collected plasma circulating tumor DNA and tumor-DNA in lung cancer patients.
Journal of thoracic disease Dec, 2020 | Pubmed ID: 33447418
Survival benefit and toxicity profile of adjuvant icotinib for patients with mutation-positive non-small cell lung carcinoma: a retrospective study.
Translational lung cancer research Dec, 2020 | Pubmed ID: 33489802
Morphine-3-glucuronide upregulates PD-L1 expression TLR4 and promotes the immune escape of non-small cell lung cancer.
Cancer biology & medicine Feb, 2021 | Pubmed ID: 33628591
Corrigendum to "Genetic Mutations of Tim-3 Ligand and Exhausted Tim-3 CD8 T Cells and Survival in Diffuse Large B Cell Lymphoma".
Journal of immunology research , 2021 | Pubmed ID: 33628842
Vorolanib, an oral VEGFR/PDGFR dual tyrosine kinase inhibitor for treatment of patients with advanced solid tumors: An open-label, phase I dose escalation and dose expansion trial.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu Feb, 2021 | Pubmed ID: 33707933
Lung cancer-associated mesenchymal stem cells promote tumor metastasis and tumorigenesis by induction of epithelial-mesenchymal transition and stem-like reprogram.
Aging Mar, 2021 | Pubmed ID: 33744858
Single-Cell Sequencing Reveals the Transcriptome and TCR Characteristics of pTregs and Expanded iTregs.
Frontiers in immunology , 2021 | Pubmed ID: 33868236
Reduced radiotherapy clinical benefit for primary Waldeyer's ring diffuse large B-cell lymphoma in the rituximab era.
Hematological oncology Oct, 2021 | Pubmed ID: 33908077
Myeloid-derived suppressor cells regulate the immunosuppressive functions of PD-1PD-L1 Bregs through PD-L1/PI3K/AKT/NF-κB axis in breast cancer.
Cell death & disease May, 2021 | Pubmed ID: 33967272
Identification of Key Genes With Differential Correlations in Lung Adenocarcinoma.
Frontiers in cell and developmental biology , 2021 | Pubmed ID: 34026765
Neoadjuvant chemoimmunotherapy in resectable stage IIIA/IIIB non-small cell lung cancer.
Translational lung cancer research May, 2021 | Pubmed ID: 34164269
An Immune-Clinical Prognostic Index (ICPI) for Patients With Follicular Lymphoma Treated With R-CHOP/CHOP Chemotherapy.
Frontiers in oncology , 2021 | Pubmed ID: 34336695
Updated Overall Survival Data and Predictive Biomarkers of Sintilimab Plus Pemetrexed and Platinum as First-Line Treatment for Locally Advanced or Metastatic Nonsquamous NSCLC in the Phase 3 ORIENT-11 Study.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Dec, 2021 | Pubmed ID: 34358724
TIM-3 and CEACAM1 are Prognostic Factors in Head and Neck Squamous Cell Carcinoma.
Frontiers in molecular biosciences , 2021 | Pubmed ID: 34368221
Ferritin as a diagnostic, differential diagnostic, and prognostic marker for immune-related adverse events.
Cancer biology & medicine Aug, 2021 | Pubmed ID: 34378879
Somatic copy number alterations are predictive of progression-free survival in patients with lung adenocarcinoma undergoing radiotherapy.
Cancer biology & medicine Aug, 2021 | Pubmed ID: 34448554
The prognostic landscape of genes and infiltrating immune cells in cytokine induced killer cell treated-lung squamous cell carcinoma and adenocarcinoma.
Cancer biology & medicine Aug, 2021 | Pubmed ID: 34459571
Bortezomib enhances the anti-cancer effect of the novel Bruton's tyrosine kinase inhibitor (BGB-3111) in mantle cell lymphoma expressing BTK.
Aging Sep, 2021 | Pubmed ID: 34508613
Programmed Cell Death Protein 1/Programmed Cell Death Ligand-1 Axis activates Intracellular ERK Signaling in Tumor Cells to Mediate Poor Prognosis in T-cell Lymphoma.
Journal of Cancer , 2021 | Pubmed ID: 34539885
Insights into tertiary lymphoid structures in the solid tumor microenvironment: anti-tumor mechanism, functional regulation, and immunotherapeutic strategies.
Cancer biology & medicine Sep, 2021 | Pubmed ID: 34553849
EZH2 identifies the precursors of human natural killer cells with trained immunity.
Cancer biology & medicine Sep, 2021 | Pubmed ID: 34553850
Tracking the evolution of untreated high-intermediate/high-risk diffuse large B-cell lymphoma by circulating tumour DNA.
British journal of haematology Feb, 2022 | Pubmed ID: 34664256
Comprehensive analysis of TP53 mutation characteristics and identification of patients with inferior prognosis and enhanced immune escape in diffuse large B-cell lymphoma.
American journal of hematology Jan, 2022 | Pubmed ID: 34710245
The Distinct Impact of TAM Infiltration on the Prognosis of Patients With Cardia and Non-Cardia Gastric Cancer and Its Association With Infection.
Frontiers in oncology , 2021 | Pubmed ID: 34926251
The Sequence of Chemotherapy and Toripalimab Might Influence the Efficacy of Neoadjuvant Chemoimmunotherapy in Locally Advanced Esophageal Squamous Cell Cancer-A Phase II Study.
Frontiers in immunology , 2021 | Pubmed ID: 34938292
Somatic copy number alteration predicts clinical benefit of lung adenocarcinoma patients treated with cytokine-induced killer plus chemotherapy.
Cancer gene therapy Aug, 2022 | Pubmed ID: 35022521
High Complete Response Rate in Patients With Metastatic Renal Cell Carcinoma Receiving Autologous Cytokine-Induced Killer Cell Therapy Plus Anti-Programmed Death-1 Agent: A Single-Center Study.
Frontiers in immunology , 2021 | Pubmed ID: 35058923
A phase I study of FCN-411, a pan-HER inhibitor, in EGFR-mutated advanced NSCLC after progression on EGFR tyrosine kinase inhibitors.
Lung cancer (Amsterdam, Netherlands) Apr, 2022 | Pubmed ID: 35248866
Downregulation of PD-L1 and HLA-I in non-small cell lung cancer with ALK fusion.
Thoracic cancer Apr, 2022 | Pubmed ID: 35253386
Safety and effectiveness of pembrolizumab combined with paclitaxel and cisplatin as neoadjuvant therapy followed by surgery for locally advanced resectable (stage III) esophageal squamous cell carcinoma: a study protocol for a prospective, single-arm, single-center, open-label, phase-II trial (Keystone-001).
Annals of translational medicine Feb, 2022 | Pubmed ID: 35280363
Genetic characteristics involving the PD-1/PD-L1/L2 and CD73/A2aR axes and the immunosuppressive microenvironment in DLBCL.
Journal for immunotherapy of cancer Apr, 2022 | Pubmed ID: 35365585
A novel clinical immune-related prognostic model predicts the overall survival of mantle cell lymphoma.
Hematological oncology Aug, 2022 | Pubmed ID: 35368100
PIM1 genetic alterations associated with distinct molecular profiles, phenotypes and drug responses in diffuse large B-cell lymphoma.
Clinical and translational medicine Apr, 2022 | Pubmed ID: 35415904
Prediction of immune-related adverse events in non-small cell lung cancer patients treated with immune checkpoint inhibitors based on clinical and hematological markers: Real-world evidence.
Experimental cell research Jul, 2022 | Pubmed ID: 35427598
Pembrolizumab Combined With Neoadjuvant Chemotherapy Versus Neoadjuvant Chemoradiotherapy Followed by Surgery for Locally Advanced Oesophageal Squamous Cell Carcinoma: Protocol for a Multicentre, Prospective, Randomized-Controlled, Phase III Clinical Study (Keystone-002).
Frontiers in oncology , 2022 | Pubmed ID: 35433421
Relationship and prognostic significance of IL-33, PD-1/PD-L1, and tertiary lymphoid structures in cervical cancer.
Journal of leukocyte biology Dec, 2022 | Pubmed ID: 35501298
CD4 T cells are required to improve the efficacy of CIK therapy in non-small cell lung cancer.
Cell death & disease May, 2022 | Pubmed ID: 35523765
Screening of Adverse Prognostic Factors and Construction of Prognostic Index in Previously Untreated Concurrent Follicular Lymphoma and Diffuse Large B-Cell Lymphoma.
BioMed research international , 2022 | Pubmed ID: 35655476
Tumor-Resident T Cells, Associated With Tertiary Lymphoid Structure Maturity, Improve Survival in Patients With Stage III Lung Adenocarcinoma.
Frontiers in immunology , 2022 | Pubmed ID: 35663939
PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway.
Molecular oncology Aug, 2022 | Pubmed ID: 35674458
Dysregulated Th1 cells in lung squamous cell carcinoma.
Journal of leukocyte biology Dec, 2022 | Pubmed ID: 35686499
m6A-Regulator Expression Signatures Identify a Subset of Follicular Lymphoma Harboring an Exhausted Tumor Microenvironment.
Frontiers in immunology , 2022 | Pubmed ID: 35734168
Trained Immunity of IL-12-, IL-15-, and IL-18-Induced CD+CD+ NKT-Like Cells.
Journal of oncology , 2022 | Pubmed ID: 35783158
Single-cell profiling of immune cells after neoadjuvant pembrolizumab and chemotherapy in IIIA non-small cell lung cancer (NSCLC).
Cell death & disease Jul, 2022 | Pubmed ID: 35831283
A 9-LncRNA Signature for Predicting Prognosis and Immune Response in Diffuse Large B-Cell Lymphoma.
Frontiers in immunology , 2022 | Pubmed ID: 35874768
Cancer immunology and immunotherapy.
Cancer biology & medicine Nov, 2021 | Pubmed ID: 35959962
A Phase IB Trial of Autologous Cytokine-Induced Killer Cells in Combination with Sintilimab, Monoclonal Antibody Against Programmed Cell Death-1, plus Chemotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Clinical lung cancer Dec, 2022 | Pubmed ID: 35995696
A novel immune-related epigenetic signature based on the transcriptome for predicting the prognosis and therapeutic response of patients with diffuse large B-cell lymphoma.
Clinical immunology (Orlando, Fla.) Oct, 2022 | Pubmed ID: 36055572
The prognostic value of a 4-factor neoimmunologic score system in non-small cell lung cancer.
Journal of leukocyte biology Dec, 2022 | Pubmed ID: 36073781
Safety and effectiveness of apatinib in elderly patients with metastatic gastric cancer: a sub-analysis from the large-scale, prospective observational study of apatinib for gastric cancer treatment in a real-world clinical setting (AHEAD-G202).
Journal of gastrointestinal oncology Aug, 2022 | Pubmed ID: 36092345
Clinical features and outcomes of patients with follicular lymphoma: A real-world study of 926 patients in China.
Frontiers in oncology , 2022 | Pubmed ID: 36185179
Rational pemetrexed combined with CIK therapy plus anti-PD-1 mAbs administration sequence will effectively promote the efficacy of CIK therapy in non-small cell lung cancer.
Cancer gene therapy Feb, 2023 | Pubmed ID: 36352092
Camrelizumab Plus Carboplatin and Pemetrexed as First-Line Treatment for Advanced Nonsquamous NSCLC: Extended Follow-Up of CameL Phase 3 Trial.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer May, 2023 | Pubmed ID: 36646210
Therapeutic effect of haploidentical peripheral blood stem cell treatment on relapsed/refractory ovarian cancer.
Bulletin du cancer Mar, 2023 | Pubmed ID: 36739242
SOCS3 deficiency-dependent autophagy repression promotes the survival of early-stage myeloid-derived suppressor cells in breast cancer by activating the Wnt/mTOR pathway.
Journal of leukocyte biology May, 2023 | Pubmed ID: 36808484
[Study on the Biological Function of Abemecilib in Inhibiting the Proliferation, Invasion and Migration of Small Cell Lung Cancer with High c-Myc Expression].
Zhongguo fei ai za zhi = Chinese journal of lung cancer Feb, 2023 | Pubmed ID: 36872049
Novel strategies for cancer immunotherapy: counter-immunoediting therapy.
Journal of hematology & oncology Apr, 2023 | Pubmed ID: 37055849
DC101, an anti-VEGFR2 agent, promotes high-endothelial venule formation and immune infiltration versus SAR131675 and fruquintinib.
Biochemical and biophysical research communications Jun, 2023 | Pubmed ID: 37084488
OX40 shapes an inflamed tumor immune microenvironment and predicts response to immunochemotherapy in diffuse large B-cell lymphoma.
Clinical immunology (Orlando, Fla.) Jun, 2023 | Pubmed ID: 37150239
PD-1 blockade potentiates neoadjuvant chemotherapy in NSCLC via increasing CD127 and KLRG1 CD8 T cells.
NPJ precision oncology May, 2023 | Pubmed ID: 37231145
Integrative genomic and transcriptomic analysis reveals genetic alterations associated with the early progression of follicular lymphoma.
British journal of haematology Sep, 2023 | Pubmed ID: 37455019
In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma.
Cell death discovery Sep, 2023 | Pubmed ID: 37666810
Effect of Chemotherapeutics on In Vitro Immune Checkpoint Expression in Non-Small Cell Lung Cancer.
Technology in cancer research & treatment , 2023 | Pubmed ID: 37728201
Blocking Tim-3 enhances the anti-tumor immunity of STING agonist ADU-S100 by unleashing CD4 T cells through regulating type 2 conventional dendritic cells.
Theranostics , 2023 | Pubmed ID: 37771774
Single-cell transcriptomics reveals tumor-infiltrating B cell function after neoadjuvant pembrolizumab and chemotherapy in non-small cell lung cancer.
Journal of leukocyte biology Sep, 2024 | Pubmed ID: 37931147
Correction: In vitro CRISPR screening uncovers CRTC3 as a regulator of IFN-γ-induced ferroptosis of hepatocellular carcinoma.
Cell death discovery Dec, 2023 | Pubmed ID: 38110330
Examining the spatial distribution of tumor-infiltrating immune cells in patients with stage I to IIIA LUAD.
Journal of leukocyte biology Sep, 2024 | Pubmed ID: 38236199
Cytokine-induced killer (CIK) cells, successes and challenges: report on the first international conference dedicated to the clinical translation of this unique adoptive cell immunotherapy.
Cancer immunology, immunotherapy : CII Jan, 2024 | Pubmed ID: 38279995
The spatial landscape of T cells in the microenvironment of stage III lung adenocarcinoma.
The Journal of pathology Apr, 2024 | Pubmed ID: 38361487
STING licensing of type I dendritic cells potentiates antitumor immunity.
Science immunology Feb, 2024 | Pubmed ID: 38363830
Anlotinib and anti-PD-1 mAbs perfected CIK cell therapy for lung adenocarcinoma in preclinical trials.
Journal of leukocyte biology Sep, 2024 | Pubmed ID: 38373017
Effects of immunogenic cell death-inducing chemotherapeutics on the immune cell activation and tertiary lymphoid structure formation in melanoma.
Frontiers in immunology , 2024 | Pubmed ID: 38384466
Immune checkpoint ligands expressed on mature high endothelial venules predict poor prognosis of NSCLC: have a relationship with CD8 T lymphocytes infiltration.
Frontiers in immunology , 2024 | Pubmed ID: 38390332
Epidemiological features and prognosis for primary gastrointestinal follicular lymphoma.
British journal of haematology May, 2024 | Pubmed ID: 38447995
PGAM1 suppression remodels the tumor microenvironment in triple-negative breast cancer and synergizes with anti-PD-1 immunotherapy.
Journal of leukocyte biology Sep, 2024 | Pubmed ID: 38478709
Intratumor tertiary lymphatic structure evaluation predicts the prognosis and immunotherapy response of patients with colorectal cancer.
Frontiers in immunology , 2024 | Pubmed ID: 38500886
XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial.
Signal transduction and targeted therapy Apr, 2024 | Pubmed ID: 38565886
The Role of Natural Killer Cells in the Tumor Immune Microenvironment of EBV-Associated Nasopharyngeal Carcinoma.
Cancers Mar, 2024 | Pubmed ID: 38610990
Peripheral NK cells identified as the predictor of response in extensive-stage small cell lung cancer patients treated with first-line immunotherapy plus chemotherapy.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico Oct, 2024 | Pubmed ID: 38662170
Phosphoglycerate mutase 1 promotes breast cancer progression through inducing immunosuppressive M2 macrophages.
Cancer gene therapy Jul, 2024 | Pubmed ID: 38750301
The antitumor effect of extracellular vesicles derived from cytokine-activated CD8+ T cells.
Journal of leukocyte biology Nov, 2024 | Pubmed ID: 38753658
Corrigendum: Intratumor tertiary lymphatic structure evaluation predicts the prognosis and immunotherapy response of patients with colorectal cancer.
Frontiers in immunology , 2024 | Pubmed ID: 38947311
Establishment of an animal model of immune-related adverse events induced by immune checkpoint inhibitors.
Cancer medicine Jul, 2024 | Pubmed ID: 39001676
Novel FABP4C1q macrophages enhance antitumor immunity and associated with response to neoadjuvant pembrolizumab and chemotherapy in NSCLC via AMPK/JAK/STAT axis.
Cell death & disease Oct, 2024 | Pubmed ID: 39353883
Toripalimab in combination with HBM4003, an anti-CTLA-4 heavy chain-only antibody, in advanced melanoma and other solid tumors: an open-label phase I trial.
Journal for immunotherapy of cancer Oct, 2024 | Pubmed ID: 39366752
A prospective study of neoadjuvant pembrolizumab plus chemotherapy for resectable esophageal squamous cell carcinoma: The Keystone-001 trial.
Cancer cell Oct, 2024 | Pubmed ID: 39406186
Advances in adoptive cellular immunotherapy and therapeutic breakthroughs in multiple myeloma.
Experimental hematology & oncology Oct, 2024 | Pubmed ID: 39468695
First-line treatment with gefitinib in combination with bevacizumab and chemotherapy in advanced non-squamous NSCLC with EGFR-mutation.
BMC cancer Oct, 2024 | Pubmed ID: 39472861
Association of concomitant H1 antihistamine and immune checkpoint inhibitor therapy on survival outcome and safety in patients with advanced primary lung cancer: a cohort study.
Translational lung cancer research Oct, 2024 | Pubmed ID: 39507043
Camrelizumab plus carboplatin and pemetrexed as first-line therapy for advanced non-squamous non-small-cell lung cancer: 5-year outcomes of the CameL randomized phase 3 study.
Journal for immunotherapy of cancer Nov, 2024 | Pubmed ID: 39608979
Elucidating the synergistic roles of CD4+ T and dendritic cells in antitumor immunity.
Cancer biology & medicine Dec, 2024 | Pubmed ID: 39663761
Xiangqin Zhao1,
Xinbo Gao1,
Wenwen Yu2,
Yi Lu1,
Xuesong Li1,
Lu Tan3,
Xiubao Ren2,
Yifei Wang1,
Weijie Song4,
Jihui Hao1,
Ying Ma1
1Department of Pancreatic Cancer, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin Key Laboratory of Digestive Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital,
2Department of Immunology and Biotherapy, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Immunology and Biotherapy, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital,
3Research Core Facility, School of Basic Medical Sciences, Tianjin Medical University,
4Department of Public Laboratory, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital
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