Timm Schroeder

Stem Cell Dynamics, Helmholtz Zentrum München - German Research Center for Environmental Health

Affiliated withHelmholtz Zentrum München - German Research Center for Environmental Health ETH Zurich Eidgenössische Technische Hochschule (ETH) Zurich

Research Area

MedicineNeuroscience

Biography

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JoVE Journal Publications

Article Total : 3	Year
Publication title	2013
Publication title	2017
Publication title	2017

Other Publications

Article	Year
Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development. Mechanisms of development\| PubMed ID: 16822655	2006
Transient expression of PU.1 commits multipotent progenitors to a myeloid fate whereas continued expression favors macrophage over granulocyte differentiation. Experimental hematology\| PubMed ID: 12543105	2003
Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12655061	2003
Dendritic cells under influence of mouse cytomegalovirus have a physiologic dual role: to initiate and to restrict T cell activation. The Journal of infectious diseases\| PubMed ID: 12660946	2003
Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12759431	2003
Generation of optimized yellow and red fluorescent proteins with distinct subcellular localization. BioTechniques\| PubMed ID: 15038157	2004
Tracking hematopoiesis at the single cell level. Annals of the New York Academy of Sciences\| PubMed ID: 15958713	2005
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Molecular biology of the cell\| PubMed ID: 16014609	2005
Common themes and cell type specific variations of higher order chromatin arrangements in the mouse. BMC cell biology\| PubMed ID: 16336643	2005
Adrenomedullin/cyclic AMP pathway induces Notch activation and differentiation of arterial endothelial cells from vascular progenitors. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 16809546	2006
The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nature neuroscience\| PubMed ID: 16892058	2006
MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17099067	2007
mNotch1 signaling and erythropoietin cooperate in erythroid differentiation of multipotent progenitor cells and upregulate beta-globin. Experimental hematology\| PubMed ID: 17637499	2007
Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17687043	2007
Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex. Development (Cambridge, England)\| PubMed ID: 18032449	2008
Notch signaling in embryonic and adult myelopoiesis. Cells, tissues, organs\| PubMed ID: 18196925	2008
Exploring hematopoiesis at single cell resolution. Cells, tissues, organs\| PubMed ID: 18230950	2008
Asymmetric Cell Division in Normal and Malignant Hematopoietic Precursor Cells. Cell stem cell\| PubMed ID: 18371383	2007
Imaging stem-cell-driven regeneration in mammals. Nature\| PubMed ID: 18480816	2008
Asymmetric cell division in normal and malignant hematopoietic precursor cells. Cell stem cell\| PubMed ID: 18938740	2007
Improved prospective identification of megakaryocyte-erythrocyte progenitor cells. British journal of haematology\| PubMed ID: 19036095	2009
Continuous single-cell imaging of blood generation from haemogenic endothelium. Nature\| PubMed ID: 19212410	2009
Late origin of glia-restricted progenitors in the developing mouse cerebral cortex. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 19363148	2009
Hematopoietic cytokines can instruct lineage choice. Science (New York, N.Y.)\| PubMed ID: 19590005	2009
Analyzing cell fate control by cytokines through continuous single cell biochemistry. Journal of cellular biochemistry\| PubMed ID: 19626666	2009
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis. Blood\| PubMed ID: 19779039	2009
Instruction of lineage choice by hematopoietic cytokines. Cell cycle (Georgetown, Tex.)\| PubMed ID: 19949300	2009
The electronic crystal ball: predicting cell fate from time-lapse data. Nature methods\| PubMed ID: 20195252	2010
Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior. Cell stem cell\| PubMed ID: 20207223	2010
Directing astroglia from the cerebral cortex into subtype specific functional neurons. PLoS biology\| PubMed ID: 20502524	2010
The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin Î±A. Neuron\| PubMed ID: 21092858	2010
Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21285961	2011
Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortex. Nature protocols\| PubMed ID: 21293461	2011
Multi-type branching models to describe cell differentiation programs. Journal of theoretical biology\| PubMed ID: 21333658	2011
Continuous live imaging of adult neural stem cell division and lineage progression in vitro. Development (Cambridge, England)\| PubMed ID: 21343361	2011
Long-term single-cell imaging of mammalian stem cells. Nature methods\| PubMed ID: 21451514	2011
Wnt to notch relay signaling induces definitive hematopoiesis. Cell stem cell\| PubMed ID: 21726826	2011
Functionally defined substates within the human embryonic stem cell compartment. Stem cell research\| PubMed ID: 21763622	2011
Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network. PloS one\| PubMed ID: 21853041	2011
The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex. Development (Cambridge, England)\| PubMed ID: 22031545	2011
Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level. Nature protocols\| PubMed ID: 22051798	2011
Advances in tracking hematopoiesis at the single-cell level. Current opinion in hematology\| PubMed ID: 22555393	2012
Multi-scale modeling of GMP differentiation based on single-cell genealogies. The FEBS journal\| PubMed ID: 22708849	2012
Stem cell powwow in Squaw Valley. Development (Cambridge, England)\| PubMed ID: 22736242	2012
Molecular live cell bioimaging in stem cell research. Annals of the New York Academy of Sciences\| PubMed ID: 22901252	2012
Hematopoiesis. Cold Spring Harbor perspectives in biology\| PubMed ID: 23209149	2012
Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling. Nature cell biology\| PubMed ID: 23644466	2013
Heterogeneity of sister cell fates. Nature reviews. Molecular cell biology\| PubMed ID: 23698579	2013
Biallelic expression of nanog protein in mouse embryonic stem cells. Cell stem cell\| PubMed ID: 23827706	2013
HSC-explorer: a curated database for hematopoietic stem cells. PloS one\| PubMed ID: 23936191	2013
Probing cellular processes by long-term live imaging--historic problems and current solutions. Journal of cell science\| PubMed ID: 23943879	2013
An automatic method for robust and fast cell detection in bright field images from high-throughput microscopy. BMC bioinformatics\| PubMed ID: 24090363	2013
Prdm6 is essential for cardiovascular development in vivo. PloS one\| PubMed ID: 24278461	2013
Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24302766	2013
Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level. Nature communications\| PubMed ID: 24326267	2013
C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors. PLoS genetics\| PubMed ID: 24415956	2014
Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell\| PubMed ID: 24439387	2014
Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases astrogliogenesis. Frontiers in cellular neuroscience\| PubMed ID: 24653675	2014
Human Pancreatic Cancer-Associated Stellate Cells Remain Activated after in vivo Chemoradiation. Frontiers in oncology\| PubMed ID: 24847445	2014
Circulation-independent differentiation pathway from extraembryonic mesoderm toward hematopoietic stem cells via hemogenic angioblasts. Cell reports\| PubMed ID: 24981862	2014
Instruction of hematopoietic lineage choice by cytokine signaling. Experimental cell research\| PubMed ID: 25046868	2014
Cytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells. Stem cell reports\| PubMed ID: 25068120	2014
Single-cell technologies sharpen up mammalian stem cell research. Nature cell biology\| PubMed ID: 25271480	2014
Marker-free detection of progenitor cell differentiation by analysis of Brownian motion in micro-wells. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 25514157	2015
Quantitative single-cell approaches to stem cell research. Cell stem cell\| PubMed ID: 25517464	2014
Factor graph analysis of live cell-imaging data reveals mechanisms of cell fate decisions. Bioinformatics (Oxford, England)\| PubMed ID: 25638814	2015
Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells. Nature\| PubMed ID: 25707806	2015
Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal. Cell reports\| PubMed ID: 26095368	2015
Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors. Cell stem cell\| PubMed ID: 26299573	2015
Network plasticity of pluripotency transcription factors in embryonic stem cells. Nature cell biology\| PubMed ID: 26389663	2015
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors. Blood\| PubMed ID: 26463424	2016
Ectopic expression of Msx2 in mammalian myotubes recapitulates aspects of amphibian muscle dedifferentiation. Stem cell research\| PubMed ID: 26468601	2015
STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling. Nature communications\| PubMed ID: 26603207	2015
Seamless Combination of Fluorescence-Activated Cell Sorting and Hanging-Drop Networks for Individual Handling and Culturing of Stem Cells and Microtissue Spheroids. Analytical chemistry\| PubMed ID: 26694967	2016
DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival. Stem cells (Dayton, Ohio)\| PubMed ID: 26731607	2016
Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming. Cell stem cell\| PubMed ID: 26748418	2016
Nanog dynamics in single embryonic stem cells. Cell cycle (Georgetown, Tex.)\| PubMed ID: 26760119	2016
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal. Nature cell biology\| PubMed ID: 27111842	2016
A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity. Nature communications\| PubMed ID: 27301576	2016
Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification. Blood\| PubMed ID: 27365423	2016
Software tools for single-cell tracking and quantification of cellular and molecular properties. Nature biotechnology\| PubMed ID: 27404877	2016
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature\| PubMed ID: 27411635	2016
Challenges in long-term imaging and quantification of single-cell dynamics. Nature biotechnology\| PubMed ID: 27824848	2016
Analysis of Cell Lineage Trees by Exact Bayesian Inference Identifies Negative Autoregulation of Nanog in Mouse Embryonic Stem Cells. Cell systems\| PubMed ID: 27883891	2016
Continuous single cell imaging reveals sequential steps of plasmacytoid dendritic cell development from common dendritic cell progenitors. Scientific reports\| PubMed ID: 27892478	2016
Activity-Independent Effects of CREB on Neuronal Survival and Differentiation during Mouse Cerebral Cortex Development. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 27999124	2016
CSF-1-induced Src signaling can instruct monocytic lineage choice. Blood\| PubMed ID: 28159742	2017
Prospective identification of hematopoietic lineage choice by deep learning. Nature methods\| PubMed ID: 28218899	2017
fastER: a user-friendly tool for ultrafast and robust cell segmentation in large-scale microscopy. Bioinformatics (Oxford, England)\| PubMed ID: 28334115	2017
Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. Cancer cell\| PubMed ID: 28399410	2017
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy. Cell\| PubMed ID: 28479188	2017
Challenges and emerging directions in single-cell analysis. Genome biology\| PubMed ID: 28482897	2017
A BaSiC tool for background and shading correction of optical microscopy images. Nature communications\| PubMed ID: 28594001	2017
Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes. Stem cell reports\| PubMed ID: 28602612	2017