Timm Schroeder

Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development.

Transient expression of PU.1 commits multipotent progenitors to a myeloid fate whereas continued expression favors macrophage over granulocyte differentiation.

Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis.

Dendritic cells under influence of mouse cytomegalovirus have a physiologic dual role: to initiate and to restrict T cell activation.

Notch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression.

Generation of optimized yellow and red fluorescent proteins with distinct subcellular localization.

Tracking hematopoiesis at the single cell level.

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells.

Common themes and cell type specific variations of higher order chromatin arrangements in the mouse.

Adrenomedullin/cyclic AMP pathway induces Notch activation and differentiation of arterial endothelial cells from vascular progenitors.

The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface.

MAPK phosphatase-1 represents a novel anti-inflammatory target of glucocorticoids in the human endothelium.

mNotch1 signaling and erythropoietin cooperate in erythroid differentiation of multipotent progenitor cells and upregulate beta-globin.

Functional properties of neurons derived from in vitro reprogrammed postnatal astroglia.

Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex.

Notch signaling in embryonic and adult myelopoiesis.

Exploring hematopoiesis at single cell resolution.

Asymmetric Cell Division in Normal and Malignant Hematopoietic Precursor Cells.

Imaging stem-cell-driven regeneration in mammals.

Asymmetric cell division in normal and malignant hematopoietic precursor cells.

Improved prospective identification of megakaryocyte-erythrocyte progenitor cells.

Continuous single-cell imaging of blood generation from haemogenic endothelium.

Late origin of glia-restricted progenitors in the developing mouse cerebral cortex.

Hematopoietic cytokines can instruct lineage choice.

Analyzing cell fate control by cytokines through continuous single cell biochemistry.

The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.

Instruction of lineage choice by hematopoietic cytokines.

The electronic crystal ball: predicting cell fate from time-lapse data.

Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior.

Directing astroglia from the cerebral cortex into subtype specific functional neurons.

The transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin αA.

Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming.

Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortex.

Multi-type branching models to describe cell differentiation programs.

Continuous live imaging of adult neural stem cell division and lineage progression in vitro.

Long-term single-cell imaging of mammalian stem cells.

Wnt to notch relay signaling induces definitive hematopoiesis.

Functionally defined substates within the human embryonic stem cell compartment.

Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network.

The role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortex.

Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level.

Advances in tracking hematopoiesis at the single-cell level.

Multi-scale modeling of GMP differentiation based on single-cell genealogies.

Stem cell powwow in Squaw Valley.

Molecular live cell bioimaging in stem cell research.

Hematopoiesis.

Oligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signalling.

Heterogeneity of sister cell fates.

Biallelic expression of nanog protein in mouse embryonic stem cells.

HSC-explorer: a curated database for hematopoietic stem cells.

Probing cellular processes by long-term live imaging--historic problems and current solutions.

An automatic method for robust and fast cell detection in bright field images from high-throughput microscopy.

Prdm6 is essential for cardiovascular development in vivo.

Incomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cells.

Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level.

C/EBPα is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors.

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.

Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases astrogliogenesis.

Human Pancreatic Cancer-Associated Stellate Cells Remain Activated after in vivo Chemoradiation.

Circulation-independent differentiation pathway from extraembryonic mesoderm toward hematopoietic stem cells via hemogenic angioblasts.

Instruction of hematopoietic lineage choice by cytokine signaling.

Cytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells.

Single-cell technologies sharpen up mammalian stem cell research.

Marker-free detection of progenitor cell differentiation by analysis of Brownian motion in micro-wells.

Quantitative single-cell approaches to stem cell research.

Factor graph analysis of live cell-imaging data reveals mechanisms of cell fate decisions.

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

Single-Stranded DNA-Binding Transcriptional Regulator FUBP1 Is Essential for Fetal and Adult Hematopoietic Stem Cell Self-Renewal.

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.

Network plasticity of pluripotency transcription factors in embryonic stem cells.

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors.

Ectopic expression of Msx2 in mammalian myotubes recapitulates aspects of amphibian muscle dedifferentiation.

STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling.

Seamless Combination of Fluorescence-Activated Cell Sorting and Hanging-Drop Networks for Individual Handling and Culturing of Stem Cells and Microtissue Spheroids.

DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survival.

Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming.

Nanog dynamics in single embryonic stem cells.

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal.

A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity.

Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.

Software tools for single-cell tracking and quantification of cellular and molecular properties.

Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.

Challenges in long-term imaging and quantification of single-cell dynamics.

Analysis of Cell Lineage Trees by Exact Bayesian Inference Identifies Negative Autoregulation of Nanog in Mouse Embryonic Stem Cells.

Continuous single cell imaging reveals sequential steps of plasmacytoid dendritic cell development from common dendritic cell progenitors.

Activity-Independent Effects of CREB on Neuronal Survival and Differentiation during Mouse Cerebral Cortex Development.

CSF-1-induced Src signaling can instruct monocytic lineage choice.

Prospective identification of hematopoietic lineage choice by deep learning.

fastER: a user-friendly tool for ultrafast and robust cell segmentation in large-scale microscopy.

Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.

Challenges and emerging directions in single-cell analysis.

A BaSiC tool for background and shading correction of optical microscopy images.

Lineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypes.