Karolin Luger

Biochemistry and Molecular Biology, Colorado State University

Affiliated withColorado State University

Research Area

BiologyUnit 1

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2013

Other Publications

Article	Year
Structure and dynamic properties of nucleosome core particles. FEBS letters\| PubMed ID: 15680970	2005
p300-mediated tax transactivation from recombinant chromatin: histone tail deletion mimics coactivator function. Molecular and cellular biology\| PubMed ID: 11739728	2002
The essential histone variant H2A.Z regulates the equilibrium between different chromatin conformational states. Nature structural biology\| PubMed ID: 11850638	2002
Solvent mediated interactions in the structure of the nucleosome core particle at 1.9 a resolution. Journal of molecular biology\| PubMed ID: 12079350	2002
Blocking transcription through a nucleosome with synthetic DNA ligands. Journal of molecular biology\| PubMed ID: 12144782	2002
The tail does not always wag the dog. Nature genetics\| PubMed ID: 12244314	2002
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands. Journal of molecular biology\| PubMed ID: 12559907	2003
Histone chaperones and nucleosome assembly. Current opinion in structural biology\| PubMed ID: 12581654	2003
Structure and dynamics of nucleosomal DNA. Biopolymers\| PubMed ID: 12666179	2003
Structure and dynamic behavior of nucleosomes. Current opinion in genetics & development\| PubMed ID: 12672489	2003
Tax recruitment of CBP/p300, via the KIX domain, reveals a potent requirement for acetyltransferase activity that is chromatin dependent and histone tail independent. Molecular and cellular biology\| PubMed ID: 12724399	2003
Preferential binding of the histone (H3-H4)2 tetramer by NAP1 is mediated by the amino-terminal histone tails. The Journal of biological chemistry\| PubMed ID: 12928440	2003
Crystal structures of histone Sin mutant nucleosomes reveal altered protein-DNA interactions. The EMBO journal\| PubMed ID: 14739929	2004
Reconstitution of nucleosome core particles from recombinant histones and DNA. Methods in enzymology\| PubMed ID: 14870657	2004
A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome. The Journal of biological chemistry\| PubMed ID: 15020582	2004
Molecular recognition of the nucleosomal "supergroove". Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15100411	2004
Nucleosomes containing the histone variant H2A.Bbd organize only 118 base pairs of DNA. The EMBO journal\| PubMed ID: 15257289	2004
Structural determinants for generating centromeric chromatin. Nature\| PubMed ID: 15282608	2004
Defined structural changes occur in a nucleosome upon Amt1 transcription factor binding. Journal of molecular biology\| PubMed ID: 15364568	2004
Nucleosome assembly protein 1 exchanges histone H2A-H2B dimers and assists nucleosome sliding. The Journal of biological chemistry\| PubMed ID: 15516689	2005
H2A.Z alters the nucleosome surface to promote HP1alpha-mediated chromatin fiber folding. Molecular cell\| PubMed ID: 15546624	2004
Nucleosomes in solution exist as a mixture of twist-defect states. Journal of molecular biology\| PubMed ID: 15567414	2005
Nucleosome and chromatin fiber dynamics. Current opinion in structural biology\| PubMed ID: 15837178	2005
The temperature of flash-cooling has dramatic effects on the diffraction quality of nucleosome crystals. Acta crystallographica. Section D, Biological crystallography\| PubMed ID: 15983411	2005
The core histone N-terminal tail domains function independently and additively during salt-dependent oligomerization of nucleosomal arrays. The Journal of biological chemistry\| PubMed ID: 16033758	2005
Structural characterization of the histone variant macroH2A. Molecular and cellular biology\| PubMed ID: 16107708	2005
The structure of nucleosome assembly protein 1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16432217	2006
The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA. Science (New York, N.Y.)\| PubMed ID: 16469929	2006
Dynamic nucleosomes. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology\| PubMed ID: 16506092	2006
Kaposi's sarcoma-associated herpesvirus LANA hitches a ride on the chromosome. Cell cycle (Georgetown, Tex.)\| PubMed ID: 16721045	2006
The histone variant macro-H2A preferentially forms "hybrid nucleosomes". The Journal of biological chemistry\| PubMed ID: 16803903	2006
A feed-forward repression mechanism anchors the Sin3/histone deacetylase and N-CoR/SMRT corepressors on chromatin. Molecular and cellular biology\| PubMed ID: 16809761	2006
Nucleosome core particles containing a poly(dA.dT) sequence element exhibit a locally distorted DNA structure. Journal of molecular biology\| PubMed ID: 16860337	2006
Structure and function of nucleosome assembly proteins. Biochemistry and cell biology = Biochimie et biologie cellulaire\| PubMed ID: 16936827	2006
Effects of photochemically activated alkylating agents of the FR900482 family on chromatin. Chemistry & biology\| PubMed ID: 17524986	2007
Structure of the Drosophila nucleosome core particle highlights evolutionary constraints on the H2A-H2B histone dimer. Proteins\| PubMed ID: 17957772	2008
A charged and contoured surface on the nucleosome regulates chromatin compaction. Nature structural & molecular biology\| PubMed ID: 17965723	2007
A beta-hairpin comprising the nuclear localization sequence sustains the self-associated states of nucleosome assembly protein 1. Journal of molecular biology\| PubMed ID: 18068721	2008
Histone chaperones in nucleosome eviction and histone exchange. Current opinion in structural biology\| PubMed ID: 18534842	2008
A thermodynamic model for Nap1-histone interactions. The Journal of biological chemistry\| PubMed ID: 18728017	2008
The effect of H3K79 dimethylation and H4K20 trimethylation on nucleosome and chromatin structure. Nature structural & molecular biology\| PubMed ID: 18794842	2008
Histone chaperone specificity in Rtt109 activation. Nature structural & molecular biology\| PubMed ID: 19172749	2008
Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA. Genes & development\| PubMed ID: 19339686	2009
A positive spin on the centromere. Cell\| PubMed ID: 19596232	2009
Structural and biophysical studies of human PARP-1 in complex with damaged DNA. Journal of molecular biology\| PubMed ID: 19962992	2010
Methods to characterize the effect of DNA-modifying compounds on nucleosomal DNA. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 19997884	2010
Structural characterization of H3K56Q nucleosomes and nucleosomal arrays. Biochimica et biophysica acta\| PubMed ID: 20100606	2010
Rise of the molecular machines. Current opinion in structural biology\| PubMed ID: 20133121	2010
The histone chaperone Nap1 promotes nucleosome assembly by eliminating nonnucleosomal histone DNA interactions. Molecular cell\| PubMed ID: 20347425	2010
Histone chaperones, histone acetylation, and the fluidity of the chromogenome. Journal of cellular physiology\| PubMed ID: 20432449	2010
The transcription factor Spn1 regulates gene expression via a highly conserved novel structural motif. Journal of molecular biology\| PubMed ID: 20875428	2010
Nucleosome accessibility governed by the dimer/tetramer interface. Nucleic acids research\| PubMed ID: 21177647	2011
A coupled equilibrium approach to study nucleosome thermodynamics. Methods in enzymology\| PubMed ID: 21195232	2011
Biophysical analysis and small-angle X-ray scattering-derived structures of MeCP2-nucleosome complexes. Nucleic acids research\| PubMed ID: 21278419	2011
Nucleosome structure(s) and stability: variations on a theme. Annual review of biophysics\| PubMed ID: 21332355	2011
The histone chaperone FACT: structural insights and mechanisms for nucleosome reorganization. The Journal of biological chemistry\| PubMed ID: 21454601	2011
The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. Genes & development\| PubMed ID: 21460035	2011
The linker region of macroH2A promotes self-association of nucleosomal arrays. The Journal of biological chemistry\| PubMed ID: 21532035	2011
Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes. Nature communications\| PubMed ID: 21587230	2011
Replacement of histone H3 with CENP-A directs global nucleosome array condensation and loosening of nucleosome superhelical termini. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21949362	2011
Histone chaperone FACT coordinates nucleosome interaction through multiple synergistic binding events. The Journal of biological chemistry\| PubMed ID: 21969370	2011
Understanding histone acetyltransferase Rtt109 structure and function: how many chaperones does it take? Current opinion in structural biology\| PubMed ID: 22023828	2011
Fluorescence strategies for high-throughput quantification of protein interactions. Nucleic acids research\| PubMed ID: 22121211	2012
Proteins for packaging, partitioning, processing, and proofing of nucleic acids. Current opinion in structural biology\| PubMed ID: 22261637	2012
New insights into nucleosome and chromatin structure: an ordered state or a disordered affair? Nature reviews. Molecular cell biology\| PubMed ID: 22722606	2012
Alternative modes of binding of poly(ADP-ribose) polymerase 1 to free DNA and nucleosomes. The Journal of biological chemistry\| PubMed ID: 22854955	2012
Quantifying chromatin-associated interactions: the HI-FI system. Methods in enzymology\| PubMed ID: 22910210	2012
Yeast CAF-1 assembles histone (H3-H4)2 tetramers prior to DNA deposition. Nucleic acids research\| PubMed ID: 22941638	2012
Structure of Actin-related protein 8 and its contribution to nucleosome binding. Nucleic acids research\| PubMed ID: 22977180	2012
Stability of nucleosomes containing homogenously ubiquitylated H2A and H2B prepared using semisynthesis. Journal of the American Chemical Society\| PubMed ID: 23163596	2012
Linker histone H1.0 interacts with an extensive network of proteins found in the nucleolus. Nucleic acids research\| PubMed ID: 23435226	2013
The role of the nucleosome acidic patch in modulating higher order chromatin structure. Journal of the Royal Society, Interface / the Royal Society\| PubMed ID: 23446052	2013
Evidence for monomeric actin function in INO80 chromatin remodeling. Nature structural & molecular biology\| PubMed ID: 23524535	2013
Histone chaperone FACT action during transcription through chromatin by RNA polymerase II. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23610384	2013
Chaperone Nap1 Shields Histone Surfaces Used in a Nucleosome and Can Put H2A-H2B in an Unconventional Tetrameric Form. Molecular cell\| PubMed ID: 23973327	2013