JoVE Logo

Sign In

Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro

1.6K Views

14:18 min

October 13th, 2023

DOI :

10.3791/65719-v

October 13th, 2023


Explore More Videos

Dioscin

Chapters in this video

0:00

Introduction

2:27

Preparing IgAN Model Mice for Dioscin‐Mediated IgA Nephropathy Alleviation Experiment

3:38

,Preparing Paraffin Sections of Kidney and Peyer's Patch Isolated from an IgAN Murine Model for Histological and Immunohistochemical Analyses

4:38

Histological Analysis of Kidney Tissue and Peyer's Patch Isolated from an IgAN Murine Model

6:16

Immunohistochemical Analysis of Peyer's Patch Isolated from an IgAN Murine Model

8:44

Assays for Screening Safe Concentrations and Effects of DIO on Normal DAKIKI Cells

10:51

Detecting the Effect of DIO on the mRNA and Protein Levels of C1GALT1 and Cosmc in DAKIKI Cells

Related Videos

article

09:04

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

47.1K Views

article

18:48

In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

14.1K Views

article

09:31

Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model

8.5K Views

article

09:11

Imaging of In Situ Interferon Gamma Production in the Mouse Spleen following Listeria monocytogenes Infection

9.0K Views

article

08:43

Adoptive Immunotherapy of iNKT Cells in Glucose-6-Phosphate Isomerase (G6PI)-Induced RA Mice

6.7K Views

article

08:02

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction

5.3K Views

article

05:39

Detection of MicroRNA Expression in the Kidneys of Immunoglobulin A Nephropathic Mice

1.8K Views

article

09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

1.8K Views

article

06:38

Induction of Ocular Surface Inflammation and Collection of Involved Tissues

2.2K Views

article

01:27

A Cell-Based Therapy for Autoimmune Arthritis in a Murine Model

70 Views

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2025 MyJoVE Corporation. All rights reserved