Madalyn R. Fritch

Department of Orthopaedic Surgery

University of Pittsburgh School of Medicine

BIOGRAPHY

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PUBLICATIONS

Chondrogenesis of human bone marrow mesenchymal stem cells in 3-dimensional, photocrosslinked hydrogel constructs: Effect of cell seeding density and material stiffness.

Acta biomaterialia Aug, 2017 | Pubmed ID: 28611002

Influence of cholesterol/caveolin-1/caveolae homeostasis on membrane properties and substrate adhesion characteristics of adult human mesenchymal stem cells.

Stem cell research & therapy Apr, 2018 | Pubmed ID: 29615119

Enhancing chondrogenesis and mechanical strength retention in physiologically relevant hydrogels with incorporation of hyaluronic acid and direct loading of TGF-β.

Acta biomaterialia Jan, 2019 | Pubmed ID: 30458242

Optimization of photocrosslinked gelatin/hyaluronic acid hybrid scaffold for the repair of cartilage defect.

Journal of tissue engineering and regenerative medicine Aug, 2019 | Pubmed ID: 31066519

Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling.

Handbook of experimental pharmacology , 2021 | Pubmed ID: 33471201

Enhancing the potential of aged human articular chondrocytes for high-quality cartilage regeneration.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Mar, 2021 | Pubmed ID: 33617078

Caveolin-1 mediates soft scaffold-enhanced adipogenesis of human mesenchymal stem cells.

Stem cell research & therapy Jun, 2021 | Pubmed ID: 34127047

Graphene oxide-functionalized nanocomposites promote osteogenesis of human mesenchymal stem cells via enhancement of BMP-SMAD1/5 signaling pathway.

Biomaterials Oct, 2021 | Pubmed ID: 34464823

Engineering pre-vascularized bone-like tissue from human mesenchymal stem cells through simulating endochondral ossification.

Biomaterials Apr, 2022 | Pubmed ID: 35259584

Human Mesenchymal Stem Cell-Derived Miniature Joint System for Disease Modeling and Drug Testing.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jul, 2022 | Pubmed ID: 35436042

Differences in the intrinsic chondrogenic potential of human mesenchymal stromal cells and iPSC-derived multipotent cells.

Clinical and translational medicine Dec, 2022 | Pubmed ID: 36536500

INSTITUTIONS

University of Pittsburgh School of Medicine

JOVE ARTICLES

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs

Meagan J. Makarcyzk^1,2,

Zhong Alan Li^1,3,

Ilhan Yu¹,

Haruyo Yagi¹,

Xiurui Zhang¹,

Lauren Yocum¹,

Eileen Li¹,

Madalyn R. Fritch¹,

Qi Gao⁴,

Bruce A. Bunnell⁵,

Stuart B. Goodman^4,6,

Rocky S. Tuan^1,8,

Peter G. Alexander^1,7,

Hang Lin^1,2,7

¹Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine,

²Department of Bioengineering, University of Pittsburgh Swanson School of Engineering,

³Department of Neurobiology, University of Pittsburgh School of Medicine,

⁴Department of Orthopaedic Surgery, Stanford University,

⁵Department of Microbiology, Immunology, and Genetics, University of North Texas Health Science Center,

⁶Department of Bioengineering, Stanford University,

⁷McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine,

⁸, The Chinese University of Hong Kong

Bioengineering

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Madalyn R. Fritch

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Orthopaedic Surgery

University of Pittsburgh School of Medicine

Creation of a Knee Joint-on-a-Chip for Modeling Joint Diseases and Testing Drugs

Department of Orthopaedic Surgery